5-hydroxytryptophan has been researched along with Cancer of Pancreas in 14 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 5.07 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| " In this study we examined the effects of two agents that promote cellular differentiation, sodium butyrate and hexamethylene bisacetamide, on the in vitro growth and secretory responses of a human pancreatic carcinoid (BON) and human gastrinoma (PT-2 and PT-SM) cell lines that have been established in our laboratory." | 3.68 | Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells. ( Beauchamp, RD; Haber, BE; Hsieh, J; Ishizuka, J; Karp, G; Parekh, D; Rajaraman, S; Thompson, JC; Townsend, CM, 1991) |
| "Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 2.67 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "In all carcinoid patients (18)F-DOPA PET and (11)C-5-HTP PET detected more lesions than SRS (P < ." | 1.35 | Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography. ( Brouwers, AH; de Vries, EG; Elsinga, PH; Jager, PL; Kema, IP; Koopmans, KP; Neels, OC; Sluiter, WJ; Vanghillewe, K, 2008) |
| "Carcinoid (n = 24) or pancreatic islet cell tumor (n = 23) patients with at least one lesion on conventional imaging including somatostatin receptor scintigraphy (SRS) and computed tomography (CT) scan underwent (11)C-5-hydroxytryptophan ((11)C-5-HTP) PET and 6-[F-18]fluoro-L-dihydroxy-phenylalanine ((18)F-DOPA) PET." | 1.35 | Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography. ( Brouwers, AH; de Vries, EG; Elsinga, PH; Jager, PL; Kema, IP; Koopmans, KP; Neels, OC; Sluiter, WJ; Vanghillewe, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taieb, D | 1 |
| Legmann, P | 1 |
| Prat, F | 1 |
| Chevallier, P | 1 |
| Tenenbaum, F | 1 |
| Koopmans, KP | 3 |
| Glaudemans, AW | 1 |
| van Asselt, SJ | 1 |
| Brouwers, AH | 2 |
| van Dullemen, HM | 1 |
| van der Jagt, EJ | 1 |
| Bongaerts, AH | 1 |
| Kema, IP | 2 |
| Valk, GD | 1 |
| Timmers, HJ | 1 |
| de Herder, WW | 1 |
| Feelders, RA | 1 |
| Fockens, P | 1 |
| Sluiter, WJ | 2 |
| de Vries, EG | 2 |
| Links, TP | 1 |
| PEART, WS | 1 |
| PORTER, KA | 1 |
| ROBERTSON, JI | 1 |
| SANDLER, M | 1 |
| BALDOCK, E | 1 |
| Neels, OC | 1 |
| Elsinga, PH | 1 |
| Vanghillewe, K | 1 |
| Jager, PL | 1 |
| Feldman, JM | 1 |
| Vervaert, C | 1 |
| Klatt, C | 1 |
| Seigler, HF | 1 |
| Eriksson, B | 3 |
| Bergström, M | 3 |
| Lilja, A | 3 |
| Ahlström, H | 3 |
| Långström, B | 3 |
| Oberg, K | 3 |
| Bjurling, P | 2 |
| Lindner, KJ | 1 |
| Orlefors, H | 1 |
| Sundin, A | 1 |
| Bombardieri, E | 1 |
| Maccauro, M | 1 |
| De Deckere, E | 1 |
| Savelli, G | 1 |
| Chiti, A | 1 |
| Parekh, D | 1 |
| Ishizuka, J | 1 |
| Townsend, CM | 1 |
| Haber, BE | 1 |
| Beauchamp, RD | 1 |
| Rajaraman, S | 1 |
| Karp, G | 1 |
| Hsieh, J | 1 |
| Thompson, JC | 1 |
| Soga, J | 1 |
| Tazawa, K | 1 |
| Sircus, W | 1 |
| Patchefsky, AS | 1 |
| Gordon, G | 1 |
| Harrer, WV | 1 |
| Hoch, WS | 1 |
3 reviews available for 5-hydroxytryptophan and Cancer of Pancreas
| Article | Year |
|---|---|
Other PET tracers for neuroendocrine tumors.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Carbon Radioisotopes; Humans; Intestinal Neoplasms; Neur | 2014 |
Nuclear medicine imaging of neuroendocrine tumours.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Antibodies, Monoclonal; Fluorodeoxyglucose F18; Humans; | 2001 |
Peptide-secreting tumours with special reference to the pancreas.
Topics: 5-Hydroxytryptophan; Adenoma; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Calcitonin; Catechol | 1969 |
2 trials available for 5-hydroxytryptophan and Cancer of Pancreas
| Article | Year |
|---|---|
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes | 1993 |
Positron-emission tomography as a radiological technique in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Carcinoid Tumor; Gastrointestinal Neoplasms; Humans; Inte | 1994 |
9 other studies available for 5-hydroxytryptophan and Cancer of Pancreas
| Article | Year |
|---|---|
Topographic diagnosis: respective roles of morphological and functional imaging.
Topics: 5-Hydroxytryptophan; Anatomy, Cross-Sectional; Diagnostic Imaging; Dihydroxyphenylalanine; Fluorodeo | 2013 |
EUS is superior for detection of pancreatic lesions compared with standard imaging in patients with multiple endocrine neoplasia type 1.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbon Radioisotopes; Cross-Sectional Studies; Early D | 2015 |
Carcinoid syndrome due to pancreatic-duct neoplasm secreting 5-hydroxytryptophan and 5-hydroxytryptamine.
Topics: 5-Hydroxytryptophan; Humans; Malignant Carcinoid Syndrome; Neoplasms; Pancreatic Neoplasms; Serotoni | 1963 |
Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Adult; Aged; Carbon Radioisotopes; Carcinoid Tumor; Dihydr | 2008 |
Therapy of malignant hamster insulinomas with monoamine precursors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Animals; Cricetinae; Dopamine; Droxidopa; Levodopa; Neopla | 1981 |
Positron emission tomography with 5-hydroxytryprophan in neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Female; Gastrointestinal Neoplasms; Humans; Linear Models | 1998 |
Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells.
Topics: 5-Hydroxytryptophan; Acetamides; Analysis of Variance; Butyrates; Butyric Acid; Carcinoid Tumor; Cel | 1991 |
Pathologic analysis of carcinoids. Histologic reevaluation of 62 cases.
Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Cytoplasmic Granules; Gastrointestinal Neoplasms; Histamine; H | 1971 |
Carcinoid tumor of the pancreas. Ultrastructural observations of a lymph node metastasis and comparison with bronchial carcinoid.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aldosterone; Carcinoid Tumor; Carcinoma, Adenoid C | 1974 |