5-hydroxytryptophan has been researched along with Cancer of Gastrointestinal Tract in 9 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The urinary excretion of 5-hydroxyindoleacetic acid, 5-hydroxytryptophan, serotonin, tryptamine, and tyramine and the serum serotonin concentration were determined in 38 consecutive patients with metastatic carcinoid tumors." | 7.66 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| "Four of the 23 patients with the carcinoid syndrome (15%) had markedly elevated excretion of 5-hydroxytryptophan." | 5.26 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| " Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 5.07 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "The urinary excretion of 5-hydroxyindoleacetic acid, 5-hydroxytryptophan, serotonin, tryptamine, and tyramine and the serum serotonin concentration were determined in 38 consecutive patients with metastatic carcinoid tumors." | 3.66 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| "Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 2.67 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "Patients with malignant midgut carcinoids are occasionally diagnosed with limited tumor spread, and surgery with radical intention is performed." | 1.35 | Elevated plasma chromogranin A is the first indication of recurrence in radically operated midgut carcinoid tumors. ( Cunningham, J; Eriksson, B; Granberg, D; Janson, ET; Oberg, K; Skogseid, B; Stridsberg, M; Welin, S, 2009) |
| "In three patients with carcinoid liver and/or lymph node metastases, we studied the process of tumor tracer uptake and decarboxylation by means of positron emission tomography (PET) using 5-hydroxy-L-tryptophan (5-HTP) 11C-labeled in the beta-position (HTP) and later the same day with 5-HTP 11C-labeled in the carboxyl group (HTC)." | 1.31 | Demonstration of [11C] 5-hydroxy-L-tryptophan uptake and decarboxylation in carcinoid tumors by specific positioning labeling in positron emission tomography. ( Bergström, M; Bjurling, P; Eriksson, B; Långström, B; Lindner, KJ; Oberg, K; Sundin, A, 2000) |
| "Four of the 23 patients with the carcinoid syndrome (15%) had markedly elevated excretion of 5-hydroxytryptophan." | 1.26 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Welin, S | 1 |
| Stridsberg, M | 1 |
| Cunningham, J | 1 |
| Granberg, D | 1 |
| Skogseid, B | 1 |
| Oberg, K | 5 |
| Eriksson, B | 5 |
| Janson, ET | 1 |
| Bergström, M | 4 |
| Lilja, A | 3 |
| Ahlström, H | 3 |
| Långström, B | 4 |
| Bjurling, P | 3 |
| Lindner, KJ | 2 |
| Orlefors, H | 1 |
| Sundin, A | 2 |
| Feldman, JM | 1 |
| Soga, J | 1 |
| Tazawa, K | 1 |
| Ryss, ES | 1 |
| Porst, H | 1 |
| Naas, W | 1 |
| Renger, F | 1 |
| Dökert, B | 1 |
| Platzbecker, H | 1 |
1 review available for 5-hydroxytryptophan and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
[Current views on carcinoid and the carcinoid syndrome].
Topics: 1-Propanol; 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carcinoi | 1971 |
2 trials available for 5-hydroxytryptophan and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes | 1993 |
Positron-emission tomography as a radiological technique in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Carcinoid Tumor; Gastrointestinal Neoplasms; Humans; Inte | 1994 |
6 other studies available for 5-hydroxytryptophan and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
Elevated plasma chromogranin A is the first indication of recurrence in radically operated midgut carcinoid tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoid Tumor; Chromograni | 2009 |
Positron emission tomography with 5-hydroxytryprophan in neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Female; Gastrointestinal Neoplasms; Humans; Linear Models | 1998 |
Demonstration of [11C] 5-hydroxy-L-tryptophan uptake and decarboxylation in carcinoid tumors by specific positioning labeling in positron emission tomography.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Carbon Radioisotopes; Carcinoid Tumor; Decarboxylation; | 2000 |
Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carcinoid Tumor; Female; Gastrointestinal Neoplasms; Humans; Hydro | 1978 |
Pathologic analysis of carcinoids. Histologic reevaluation of 62 cases.
Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Cytoplasmic Granules; Gastrointestinal Neoplasms; Histamine; H | 1971 |
[Carcinoid and carcinoid syndrome].
Topics: 5-Hydroxytryptophan; Bradykinin; Carcinoid Tumor; Female; Gastrointestinal Neoplasms; Hepatomegaly; | 1974 |