Compounds > 5-hydroxytryptophan
Page last updated: 2024-10-16

5-hydroxytryptophan and Bowel Diseases, Inflammatory

5-hydroxytryptophan has been researched along with Bowel Diseases, Inflammatory in 1 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Despite a significant increase in serum 5-hydroxytryptophan and serotonin levels, oral 5-hydroxytryptophan did not modulate IBD-related fatigue better than placebo."9.51Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial. ( Bos, S; Bossuyt, P; Cremer, A; De Vos, M; Dewint, P; Dewit, O; Ferrante, M; Gonzales, GB; Holvoet, T; Lambrecht, G; Laukens, D; Lobatón, T; Louis, E; Muls, V; Peeters, A; Peeters, H; Pouillon, L; Rahier, JF; Truyens, M; Vandermeulen, L; Vermeire, S, 2022)
"Fatigue is highly prevalent among patients with inflammatory bowel disease (IBD), and only limited treatment options are available."7.11Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial. ( Bos, S; Bossuyt, P; Cremer, A; De Vos, M; Dewint, P; Dewit, O; Ferrante, M; Gonzales, GB; Holvoet, T; Lambrecht, G; Laukens, D; Lobatón, T; Louis, E; Muls, V; Peeters, A; Peeters, H; Pouillon, L; Rahier, JF; Truyens, M; Vandermeulen, L; Vermeire, S, 2022)
"Despite a significant increase in serum 5-hydroxytryptophan and serotonin levels, oral 5-hydroxytryptophan did not modulate IBD-related fatigue better than placebo."5.51Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial. ( Bos, S; Bossuyt, P; Cremer, A; De Vos, M; Dewint, P; Dewit, O; Ferrante, M; Gonzales, GB; Holvoet, T; Lambrecht, G; Laukens, D; Lobatón, T; Louis, E; Muls, V; Peeters, A; Peeters, H; Pouillon, L; Rahier, JF; Truyens, M; Vandermeulen, L; Vermeire, S, 2022)
"Fatigue is highly prevalent among patients with inflammatory bowel disease (IBD), and only limited treatment options are available."3.11Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial. ( Bos, S; Bossuyt, P; Cremer, A; De Vos, M; Dewint, P; Dewit, O; Ferrante, M; Gonzales, GB; Holvoet, T; Lambrecht, G; Laukens, D; Lobatón, T; Louis, E; Muls, V; Peeters, A; Peeters, H; Pouillon, L; Rahier, JF; Truyens, M; Vandermeulen, L; Vermeire, S, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Truyens, M1
Lobatón, T1
Ferrante, M1
Bossuyt, P1
Vermeire, S1
Pouillon, L1
Dewint, P1
Cremer, A1
Peeters, H1
Lambrecht, G1
Louis, E1
Rahier, JF1
Dewit, O1
Muls, V1
Holvoet, T1
Vandermeulen, L1
Peeters, A1
Gonzales, GB1
Bos, S1
Laukens, D1
De Vos, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicentric, Double-blind, Placebo Controlled Clinical Trial With 5-hydroxytryptophan (5-HTP) in Patients With Inflammatory Bowel Disease in Clinical and Biologic Remission: Effect on Fatigue Scores[NCT03574948]Phase 2175 participants (Actual)Interventional2018-12-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for 5-hydroxytryptophan and Bowel Diseases, Inflammatory

ArticleYear
Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.
    Gastroenterology, 2022, Volume: 163, Issue:5

    Topics: 5-Hydroxytryptophan; Chronic Disease; Fatigue; Humans; Inflammatory Bowel Diseases; Serotonin; Trypt

2022