5-hydroxytryptophan has been researched along with Autotomy Human in 11 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Hydroxytryptophan (5-HTP) treatment of a single case of Lesch-Nyhan syndrome showing compulsive self-mutilation, athetoid movements, and characteristic clinical biochemical picture was studied on a double-blind basis." | 9.04 | Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome. ( Frith, CD; Johnston, EC; Joseph, MH; Powell, RJ; Watts, RW, 1976) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, and carbidopa, a peripheral aromatic amino acid decarboxylase inhibitor, were studied in a boy with the Lesch-Nyhan syndrome." | 7.66 | Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1978) |
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 7.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome." | 7.65 | The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976) |
| "5-Hydroxytryptophan (5-HTP) treatment of a single case of Lesch-Nyhan syndrome showing compulsive self-mutilation, athetoid movements, and characteristic clinical biochemical picture was studied on a double-blind basis." | 6.64 | Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome. ( Frith, CD; Johnston, EC; Joseph, MH; Powell, RJ; Watts, RW, 1976) |
| "5-Hydroxytryptophan (5-HTP) treatment of a single case of Lesch-Nyhan syndrome showing compulsive self-mutilation, athetoid movements, and characteristic clinical biochemical picture was studied on a double-blind basis." | 5.04 | Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome. ( Frith, CD; Johnston, EC; Joseph, MH; Powell, RJ; Watts, RW, 1976) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, and carbidopa, a peripheral aromatic amino acid decarboxylase inhibitor, were studied in a boy with the Lesch-Nyhan syndrome." | 3.66 | Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1978) |
| "In a patient with the Lesch-Nyhan syndrome we found decreased spinal fluid 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of serotonin, and decreased homovanillic acid (HVA), the major metabolite of dopamine, indicating a decrease in monoamine metabolism." | 3.66 | Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome. ( Castells, S; Chakrabarti, C; Hurwic, M; Nyhan, WL; Perel, JM; Winsberg, BG, 1979) |
| "The effects of 5-hydroxytryptophan (5-HTP), a serotonin precursor, were studied in a boy with the Lesch-Nyhan syndrome." | 3.65 | The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome. ( Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD, 1976) |
| "5-Hydroxytryptophan (5-HTP) treatment of a single case of Lesch-Nyhan syndrome showing compulsive self-mutilation, athetoid movements, and characteristic clinical biochemical picture was studied on a double-blind basis." | 2.64 | Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome. ( Frith, CD; Johnston, EC; Joseph, MH; Powell, RJ; Watts, RW, 1976) |
| " The dosage level was sufficient to produce undesirable side-effects (diarrhea and vomiting)." | 2.64 | The effect of L-5-hydroxytryptophan on self-mutilatin in Lesch-Nyhan disease: a negative report. ( Anderson, LT; Dancis, J; Herrmann, L, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, NN | 1 |
| Razzak, A | 1 |
| Fujiwara, M | 1 |
| Oishi, R | 1 |
| Ueki, S | 1 |
| Nyhan, WL | 3 |
| Anders, TF | 2 |
| Cann, HM | 2 |
| Ciaranello, RD | 2 |
| Barchas, JD | 2 |
| Berger, PA | 2 |
| Castells, S | 1 |
| Chakrabarti, C | 1 |
| Winsberg, BG | 1 |
| Hurwic, M | 1 |
| Perel, JM | 1 |
| Frith, CD | 1 |
| Johnston, EC | 1 |
| Joseph, MH | 1 |
| Powell, RJ | 1 |
| Watts, RW | 1 |
| Anderson, LT | 1 |
| Herrmann, L | 1 |
| Dancis, J | 1 |
| López-Ibor, JJ | 1 |
| Saiz-Ruiz, J | 1 |
| Pérez de los Cobos, JC | 1 |
| Mizuno, TI | 1 |
| Yugari, Y | 1 |
1 review available for 5-hydroxytryptophan and Autotomy Human
| Article | Year |
|---|---|
Current trends in the treatment of self-injurious behavior.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Ammonia; Aversive Therapy; Behavior Therapy; Child; Ch | 1981 |
3 trials available for 5-hydroxytryptophan and Autotomy Human
| Article | Year |
|---|---|
Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Child; Clinical Trials as Topic; Drug Evaluation; Emotions; Humans; Lesch-Nyhan | 1976 |
The effect of L-5-hydroxytryptophan on self-mutilatin in Lesch-Nyhan disease: a negative report.
Topics: 5-Hydroxytryptophan; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Lesch-Nyhan Synd | 1976 |
Letter: Self mutilation in Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Administration, Oral; Child; Dihydroxyphenylalanine; Humans; Hydroxyindoleaceti | 1974 |
7 other studies available for 5-hydroxytryptophan and Autotomy Human
| Article | Year |
|---|---|
Possible involvement of a central noradrenergic system in automutilation induced by clonidine in mice.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Caffeine; Catecholamines; Chlorpromazine; Clon | 1977 |
The Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Adolescent; Aggression; Allopurinol; Behavior Therapy; Child; Child Behavior Di | 1978 |
Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Carbidopa; Child; Drug Therapy, Combination; Humans; Hydrazines; Lesch-Nyhan Sy | 1978 |
Effects of L-5-hydroxytryptophan on monoamine and amino acids turnover in the Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Amino Acids; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleaceti | 1979 |
Behavior in the Lesch--Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Aggression; Behavior Therapy; Carbidopa; Carboxy-Lyases; Compulsive Behavior; D | 1976 |
The use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Child, Preschool; Cold Temperature; Crying; Dopamine beta-Hydroxylase; Dose-Res | 1976 |
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas | 1985 |