5-hydroxytryptophan has been researched along with Autism in 6 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results suggest that autism is accompanied by a major disequilibrium in the serotonergic system." | 6.73 | Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Spaas, K; Verkerk, R; Wauters, A, 2008) |
| "Autism is accompanied by peripheral and central disorders in the metabolism of serotonin (5-HT)." | 6.73 | Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Spaas, K; Verkerk, R; Wauters, A, 2008) |
| "The results suggest that autism is accompanied by a central serotonergic hypoactivity and that the latter could play a role in the pathophysiology of autism." | 5.34 | Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Verkerk, R; Wauters, A, 2007) |
| "The results suggest that autism is accompanied by a major disequilibrium in the serotonergic system." | 2.73 | Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Spaas, K; Verkerk, R; Wauters, A, 2008) |
| "Autism is accompanied by peripheral and central disorders in the metabolism of serotonin (5-HT)." | 2.73 | Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Spaas, K; Verkerk, R; Wauters, A, 2008) |
| "The results suggest that autism is accompanied by a central serotonergic hypoactivity and that the latter could play a role in the pathophysiology of autism." | 1.34 | Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test. ( Croonenberghs, J; Deboutte, D; Maes, M; Scharpe, S; Verkerk, R; Wauters, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Croonenberghs, J | 3 |
| Spaas, K | 1 |
| Wauters, A | 2 |
| Verkerk, R | 3 |
| Scharpe, S | 3 |
| Deboutte, D | 3 |
| Maes, M | 3 |
| Adamsen, D | 1 |
| Meili, D | 1 |
| Blau, N | 1 |
| Thöny, B | 1 |
| Ramaekers, V | 1 |
| Sverd, J | 1 |
| Kupietz, SS | 1 |
| Winsberg, BG | 1 |
| Hurwic, MJ | 1 |
| Becker, L | 1 |
| Naruse, H | 1 |
| Hayashi, T | 1 |
| Takesada, M | 1 |
| Nakane, A | 1 |
| Yamazaki, K | 1 |
4 trials available for 5-hydroxytryptophan and Autism
| Article | Year |
|---|---|
Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test.
Topics: 5-Hydroxytryptophan; Adolescent; Analysis of Variance; Autistic Disorder; Dehydroepiandrosterone Sul | 2008 |
Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Autistic Disorder; Female; Humans; Hydroxyindoleacetic Acid; | 2005 |
Effects of L-5-hydroxytryptophan in autistic children.
Topics: 5-Hydroxytryptophan; Attention; Autistic Disorder; Brain; Carbidopa; Child; Child, Preschool; Dose-R | 1978 |
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotope | 1989 |
2 other studies available for 5-hydroxytryptophan and Autism
| Article | Year |
|---|---|
Autism associated with low 5-hydroxyindolacetic acid in CSF and the heterozygous SLC6A4 gene Gly56Ala plus 5-HTTLPR L/L promoter variants.
Topics: 5-Hydroxytryptophan; Amino Acid Substitution; Antidepressive Agents, Second-Generation; Autistic Dis | 2011 |
Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Analysis of Variance; Antidepressive Agents, Second-Generati | 2007 |