5-hydroxytryptophan has been researched along with Ataxia in 4 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of serotonin in the ataxia of progressive myoclonus epilepsy, eight patients received oral 5-hydroxy-L-tryptophan (L-5-HTP) or placebo plus carbidopa for 1 month in a controlled, double-blinded, dose-ranging, cross-over, add-on study." | 2.68 | A controlled trial of 5-hydroxy-L-tryptophan for ataxia in progressive myoclonus epilepsy. ( Galvan, I; Pranzatelli, MR; Tate, E; Wheeler, A, 1996) |
| "Ataxia was evaluated using objective and subjective scales." | 2.68 | A controlled trial of 5-hydroxy-L-tryptophan for ataxia in progressive myoclonus epilepsy. ( Galvan, I; Pranzatelli, MR; Tate, E; Wheeler, A, 1996) |
| "We studied 6 patients with myoclonus elicited by flash stimulation (1-15 Hz)." | 1.29 | The pathophysiology and pharmacology of photic cortical reflex myoclonus. ( Artieda, J; Obeso, JA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feit, H | 1 |
| Kirkpatrick, J | 1 |
| Van Woert, MH | 1 |
| Pandian, G | 1 |
| Currier, RD | 1 |
| Artieda, J | 1 |
| Obeso, JA | 1 |
| Pranzatelli, MR | 1 |
| Tate, E | 1 |
| Galvan, I | 1 |
| Wheeler, A | 1 |
1 trial available for 5-hydroxytryptophan and Ataxia
| Article | Year |
|---|---|
A controlled trial of 5-hydroxy-L-tryptophan for ataxia in progressive myoclonus epilepsy.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Ataxia; Double-Blind Method; Epilepsie | 1996 |
3 other studies available for 5-hydroxytryptophan and Ataxia
| Article | Year |
|---|---|
Myoclonus, ataxia, and hypoventilation: response to L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Ataxia; Female; Humans; Hypoventilation; Mitochondria, Muscle; Myoclonus | 1983 |
A treatment for ataxia.
Topics: 5-Hydroxytryptophan; Ataxia; Clinical Trials as Topic; Humans | 1995 |
The pathophysiology and pharmacology of photic cortical reflex myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Aged, 80 and over; Ataxia; Cerebral Cortex; Dopamine Agents; Electroencep | 1993 |