5-hydroxytryptophan has been researched along with Anxiety in 19 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study fibromyalgia sufferers were randomly administered a combination of monoamine-oxidase inhibitors (MAOIs)-A/B with 5-HTP, 5-HTP alone, MAOIs-A/B alone, or the tricyclic drug amitriptyline in order to compare the efficacy of these treatments." | 5.08 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "The recently shown high prevalence of migraine in the population of fibromyalgia sufferers, suggests a common ground shared by fibromyalgia and migraine." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "Migraine has been demonstrated to be characterized by a defect in the serotonergic and adrenergic systems." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "5-Hydroxytryptophan has the opposite effect exacerbating the behavioural response to the aversive situation." | 2.38 | The pharmacology of the 5-HT4 receptor. ( Costall, B; Naylor, RJ, 1993) |
| " SNP, a nitric oxide donor, produced a bell-shaped dose-response profile on scototaxis." | 1.42 | Interactions between serotonin and glutamate-nitric oxide pathways in zebrafish scototaxis. ( Herculano, AM; Lima, MG; Maximino, C; Miranda, V; Puty, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sachs, BD | 1 |
| Jacobsen, JP | 1 |
| Thomas, TL | 1 |
| Siesser, WB | 1 |
| Roberts, WL | 1 |
| Caron, MG | 1 |
| Herculano, AM | 1 |
| Puty, B | 1 |
| Miranda, V | 1 |
| Lima, MG | 1 |
| Maximino, C | 1 |
| Eskelund, A | 1 |
| Budac, DP | 1 |
| Sanchez, C | 1 |
| Elfving, B | 1 |
| Wegener, G | 1 |
| Grillon, C | 1 |
| Chavis, C | 1 |
| Covington, MF | 1 |
| Pine, DS | 1 |
| Weeks, BS | 1 |
| Iezhitsa, IN | 1 |
| Spasov, AA | 1 |
| Kharitonova, MV | 1 |
| Kravchenko, MS | 1 |
| Yamada, I | 1 |
| Iwasaki, T | 1 |
| Cui, XY | 1 |
| Zhao, X | 1 |
| Chu, QP | 1 |
| Chen, BQ | 1 |
| Zhang, YH | 1 |
| Bechtholt, AJ | 1 |
| Hill, TE | 1 |
| Lucki, I | 1 |
| Hughes, ZA | 1 |
| Liu, F | 1 |
| Platt, BJ | 1 |
| Dwyer, JM | 1 |
| Pulicicchio, CM | 1 |
| Zhang, G | 1 |
| Schechter, LE | 1 |
| Rosenzweig-Lipson, S | 1 |
| Day, M | 1 |
| Bono, G | 1 |
| Micieli, G | 1 |
| Sances, G | 1 |
| Calvani, M | 1 |
| Nappi, G | 1 |
| Costall, B | 1 |
| Naylor, RJ | 1 |
| Nicolodi, M | 1 |
| Sicuteri, F | 1 |
| Harris, GC | 1 |
| Aston-Jones, G | 1 |
| Wilson, CA | 1 |
| Gonzalez, I | 1 |
| Farabollini, F | 1 |
| van Praag, HM | 1 |
| Kahn, R | 1 |
| Asnis, GM | 1 |
| Lemus, CZ | 1 |
| Brown, SL | 1 |
| Colpaert, FC | 1 |
| Meert, TF | 1 |
| Niemegeers, CJ | 1 |
| Janssen, PA | 1 |
| Hartmann, RJ | 1 |
| Geller, I | 1 |
| Wise, CD | 1 |
| Berger, BD | 1 |
| Stein, L | 1 |
2 reviews available for 5-hydroxytryptophan and Anxiety
| Article | Year |
|---|---|
Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anxiety; Dietary Supplements; Drug Combinations; | 2009 |
The pharmacology of the 5-HT4 receptor.
Topics: 4-Aminobenzoic Acid; 5-Hydroxytryptophan; Animals; Anxiety; Arousal; Brain; Diazepam; Disease Models | 1993 |
3 trials available for 5-hydroxytryptophan and Anxiety
| Article | Year |
|---|---|
Two-week treatment with the selective serotonin reuptake inhibitor citalopram reduces contextual anxiety but not cued fear in healthy volunteers: a fear-potentiated startle study.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Adult; Analysis of Variance; Anxiety; Citalopram; Cues; D | 2009 |
L-5HTP treatment in primary headaches: an attempt at clinical identification of responsive patients.
Topics: 5-Hydroxytryptophan; Adult; Anxiety; Chronic Disease; Clinical Trials as Topic; Depression; Female; | 1984 |
Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy.
Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Drug Therapy, Combina | 1996 |
14 other studies available for 5-hydroxytryptophan and Anxiety
| Article | Year |
|---|---|
The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; F | 2013 |
Interactions between serotonin and glutamate-nitric oxide pathways in zebrafish scototaxis.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Glutamic Acid; N-Methylaspartate; Nitric Oxide; Nitric Oxide | 2015 |
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous C | 2016 |
Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nicotine, apomorphine, and L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anxiety; Apomorphine; Arecoline; Clonidine; Depression; D | 2011 |
[Anxiety-like behavior in rats neonatally and adultly treated with 5,7-dihydroxytryptamine].
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiet | 2002 |
Influence of diltiazem on the behavior of zolpidem-treated mice in the elevated-plus maze test.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Calcium Channel Blocker | 2007 |
Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; | 2007 |
WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; | 2008 |
Augmented accumbal serotonin levels decrease the preference for a morphine associated environment during withdrawal.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Psychological; Drug Administration Schedule; En | 2001 |
Behavioural effects in adulthood of neonatal manipulation of brain serotonin levels in normal and androgenized females.
Topics: 5-Hydroxytryptophan; Androgens; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain Chemistr | 1992 |
Therapeutic indications for serotonin-potentiating compounds: a hypothesis.
Topics: 5-Hydroxytryptophan; Aggression; Antidepressive Agents; Anxiety; Brain; Depressive Disorder; Desipra | 1987 |
Behavioral and 5-HT antagonist effects of ritanserin: a pure and selective antagonist of LSD discrimination in rat.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Disease Mode | 1985 |
P-Chlorophenylalanine effects on a conditioned emotional response in rats.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Operant; Conditioning, Psychological; Electrosh | 1971 |
Serotonin: a possible mediator of behavioral suppression induced by anxiety.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Drinking Behavior; Electro | 1970 |