5-hydroxytryptophan has been researched along with Anxiety Disorders in 9 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Anxiety Disorders: Persistent and disabling ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind placebo-controlled study of 5-HTP and clomipramine was carried out on 45 patients suffering from anxiety disorders (DSM-III)." | 9.06 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "Clomipramine has shown to be effective in that it induced significant improvement on all rating scales as compared to placebo." | 6.66 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "A double-blind placebo-controlled study of 5-HTP and clomipramine was carried out on 45 patients suffering from anxiety disorders (DSM-III)." | 5.06 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "Clomipramine has shown to be effective in that it induced significant improvement on all rating scales as compared to placebo." | 2.66 | Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. ( Gispen-de Wied, CC; Kahn, RS; Kamerbeek, WD; Verhoeven, WM; Westenberg, HG, 1987) |
| "l-5-hydroxytryptophan was administered to 119 prepubertal children free of psychiatric disorder as part of a psychobiological cohort study initially designed to examine familial loading for mood disorder as the exposure of interest." | 1.32 | Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder? ( Birmaher, B; Campo, JV; Dahl, RE; Perel, JM; Ryan, ND; Williamson, DE, 2003) |
| "L-5-Hydroxytryptophan (5HTP) was administered to 20 patients suffering from panic disorder and to 20 healthy controls." | 1.28 | Behavioral, neuroendocrine, and biochemical effects of 5-hydroxytryptophan administration in panic disorder. ( den Boer, JA; Westenberg, HG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frick, A | 1 |
| Åhs, F | 1 |
| Engman, J | 1 |
| Jonasson, M | 1 |
| Alaie, I | 1 |
| Björkstrand, J | 1 |
| Frans, Ö | 1 |
| Faria, V | 1 |
| Linnman, C | 1 |
| Appel, L | 1 |
| Wahlstedt, K | 1 |
| Lubberink, M | 1 |
| Fredrikson, M | 1 |
| Furmark, T | 1 |
| Blazevic, S | 1 |
| Colic, L | 1 |
| Culig, L | 1 |
| Hranilovic, D | 1 |
| Campo, JV | 1 |
| Dahl, RE | 1 |
| Williamson, DE | 1 |
| Birmaher, B | 1 |
| Perel, JM | 1 |
| Ryan, ND | 1 |
| den Boer, JA | 2 |
| Westenberg, HG | 3 |
| van Praag, HM | 2 |
| Kahn, RS | 4 |
| Wetzler, S | 1 |
| Asnis, GM | 1 |
| Barr, G | 1 |
| Verhoeven, WM | 1 |
| Gispen-de Wied, CC | 1 |
| Kamerbeek, WD | 1 |
3 reviews available for 5-hydroxytryptophan and Anxiety Disorders
| Article | Year |
|---|---|
L-5-hydroxytryptophan in depression and anxiety.
Topics: 5-Hydroxytryptophan; Anxiety Disorders; Depressive Disorder; Humans; Panic; Receptors, Serotonin | 1988 |
Serotonin and anxiety revisited.
Topics: 5-Hydroxytryptophan; Animals; Anxiety Disorders; Benzodiazepines; Brain; Humans; Obsessive-Compulsiv | 1988 |
Biogenic amines and psychiatry.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Amines; Amphetamine; Anxiety Disorders; Attention Deficit D | 1971 |
2 trials available for 5-hydroxytryptophan and Anxiety Disorders
| Article | Year |
|---|---|
Psychopharmacology of anxiety disorders: on the role of serotonin in the treatment of anxiety states and phobic disorders.
Topics: 5-Hydroxytryptophan; Anxiety Disorders; Clomipramine; Female; Fluvoxamine; Humans; Male; Oximes; Ser | 1987 |
Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
Topics: 5-Hydroxytryptophan; Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; | 1987 |
4 other studies available for 5-hydroxytryptophan and Anxiety Disorders
| Article | Year |
|---|---|
Serotonin Synthesis and Reuptake in Social Anxiety Disorder: A Positron Emission Tomography Study.
Topics: 5-Hydroxytryptophan; Adult; Anxiety Disorders; Benzylamines; Brain; Carbon Radioisotopes; Case-Contr | 2015 |
Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiet | 2012 |
Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder?
Topics: 5-Hydroxytryptophan; Affective Symptoms; Anxiety Disorders; Child; Cohort Studies; Depressive Disord | 2003 |
Behavioral, neuroendocrine, and biochemical effects of 5-hydroxytryptophan administration in panic disorder.
Topics: 5-Hydroxytryptophan; Anxiety Disorders; Arousal; beta-Endorphin; Blood Platelets; Fear; Female; Huma | 1990 |