Page last updated: 2024-10-16

5-hydroxytryptophan and Alloxan Diabetes

5-hydroxytryptophan has been researched along with Alloxan Diabetes in 13 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Neither insulin injections nor streptozotocin diabetes had any effect on pineal melatonin production in rats."1.27Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections. ( Champney, TH; Craft, CM; Holtorf, AP; Reiter, RJ, 1986)
"1 In nialamide-treated mice, L-5-hydroxytryptophan produced a dose-dependent hypoglycaemic response which was independent of whether the animals had been fed or fasted."1.25The hypoglycaemic effect of 5-hydroxytryptophan. ( Furman, BL, 1974)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Song, L1
Zhuang, P1
Lin, M1
Kang, M1
Liu, H1
Zhang, Y2
Yang, Z1
Chen, Y1
Yamada, J1
Sugimoto, Y1
Ujikawa, M1
Goko, H1
Yagura, T1
Trulson, ME2
MacKenzie, RG2
Furman, BL3
Wilson, GA2
Cićin-Sain, L1
Jernej, B1
Shimazoe, T1
Ishida, J1
Maetani, M1
Yakabe, T1
Yamaguchi, M1
Miyasaka, K1
Kono, A1
Watanabe, S1
Funakoshi, A1
Smith, SA1
Pogson, CL1
Chen, CC1
Jacoby, JH1
Champney, TH1
Holtorf, AP1
Craft, CM1
Reiter, RJ1
Lundquist, I1
Ekholm, R1
Ericson, LE1

Other Studies

13 other studies available for 5-hydroxytryptophan and Alloxan Diabetes

ArticleYear
Urine Metabonomics Reveals Early Biomarkers in Diabetic Cognitive Dysfunction.
    Journal of proteome research, 2017, 09-01, Volume: 16, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Biomarkers; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Di

2017
Hyperleptinemia elicited by the 5-HT precursor, 5-hydroxytryptophan in mice: involvement of insulin.
    Life sciences, 2003, Sep-19, Volume: 73, Issue:18

    Topics: 5-Hydroxytryptophan; Adipose Tissue; Animals; Benserazide; Diabetes Mellitus, Experimental; Dose-Res

2003
Subsensitivity to 5-hydroxytryptamine agonists occurs in streptozocin-diabetic rats with no change in [3H]-5-HT receptor binding.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:7

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Diabetes Mellitus, Exp

1981
Further studies on the effects of 5-hydroxytryptophan on plasma glucose and insulin in the mouse.
    Diabetologia, 1980, Volume: 19, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Blood Glucose; Diabetes Mellitus, Experimental; Insulin;

1980
Effects of inhibitors of 5-hydroxytryptamine uptake on plasma glucose and their interaction with 5-hydroxytryptophan in producing hypoglycaemia in mice.
    European journal of pharmacology, 1982, Mar-12, Volume: 78, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Interactions; Fas

1982
Reduction of gastrointestinal serotonin in alloxan-diabetic rats: reversal by 5-hydroxytryptophan treatment.
    Behavioural brain research, 1996, Volume: 73, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Blood Platelets; Cell Membrane; Diabetes Mellitus, Experimental; Diges

1996
Entrainment function in the suprachiasmatic nucleus of streptozotocin-induced diabetic rats.
    Japanese journal of pharmacology, 2000, Volume: 83, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Circadian Rhythm; Diabetes Mellitus, Experimental; Glutamic Aci

2000
Tryptophan and the control of plasma glucose concentrations in the rat.
    The Biochemical journal, 1977, Dec-15, Volume: 168, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenalectomy; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fenclon

1977
Effect of the duration of streptozotocin-induced diabetes on turnover of central biogenic amines in mice.
    Neuroendocrinology, 1992, Volume: 56, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Cat

1992
Streptozotocin-induced diabetes reduces brain serotonin synthesis in rats.
    Journal of neurochemistry, 1986, Volume: 46, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Carboxy-Lyases; Diabetes Mellitus, Experimental; H

1986
Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections.
    Comparative biochemistry and physiology. A, Comparative physiology, 1986, Volume: 83, Issue:2

    Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Cr

1986
The hypoglycaemic effect of 5-hydroxytryptophan.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: 5-Hydroxytryptophan; Adipose Tissue; Animals; Blood Glucose; Cyproheptadine; Diabetes Mellitus, Expe

1974
Monoamines in the pancreatic islets of the mouse. 5-hydroxytryptamine as an intracellular modifier of insulin secretion, and the hypoglycaemic action of monoamine oxidase inhibitors.
    Diabetologia, 1971, Volume: 7, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose; Glybu

1971