5-hydroxytryptophan has been researched along with Allodynia in 6 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-HTP induces rectal allodynia in a significant number of healthy controls; IBS patients exhibit lowered pain thresholds in both placebo and 5-HTP conditions." | 2.80 | Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study. ( Buurman, WA; Dekker, J; Jonkers, DM; Keszthelyi, D; Masclee, AA; Troost, FJ; van Eijk, HM, 2015) |
| "To clarify the mechanism of the hyperalgesia in SART mice and the mode of the antinociceptive action of neurotropin in this model, the influence of systemically administered neurotransmitter related drugs was studied." | 1.28 | Mechanism of hyperalgesia in SART stressed (repeated cold stress) mice: antinociceptive effect of neurotropin. ( Hata, T; Kawamura, M; Miura, T; Namimatsu, A; Ohara, H; Yoneda, R, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, X | 1 |
| Wang, C | 1 |
| Cui, WG | 1 |
| Ma, Q | 1 |
| Zhou, WH | 1 |
| Keszthelyi, D | 1 |
| Troost, FJ | 1 |
| Jonkers, DM | 1 |
| van Eijk, HM | 1 |
| Dekker, J | 1 |
| Buurman, WA | 1 |
| Masclee, AA | 1 |
| Kulkarni, SK | 1 |
| Robert, RK | 1 |
| Nicolodi, M | 1 |
| Sicuteri, F | 1 |
| Coelho, AM | 1 |
| Jacob, L | 1 |
| Fioramonti, J | 1 |
| Bueno, L | 1 |
| Ohara, H | 1 |
| Kawamura, M | 1 |
| Namimatsu, A | 1 |
| Miura, T | 1 |
| Yoneda, R | 1 |
| Hata, T | 1 |
2 trials available for 5-hydroxytryptophan and Allodynia
| Article | Year |
|---|---|
Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Double-Blind Method; Female; Humans; Hyperalgesia; | 2015 |
L-5-hydroxytryptophan can prevent nociceptive disorders in man.
Topics: 5-Hydroxytryptophan; Analgesics; Ascorbic Acid; Child; Child, Preschool; Female; Follow-Up Studies; | 1999 |
4 other studies available for 5-hydroxytryptophan and Allodynia
| Article | Year |
|---|---|
Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Behavior, Animal; Biogenic Monoamines; Disease Models, Ani | 2015 |
Reversal by serotonergic agents of reserpine-induced hyperalgesia in rats.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Tricyclic; Female; Hyperalgesia; Hyperesthesia; | 1982 |
Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype.
Topics: 5-Hydroxytryptophan; Analgesics, Non-Narcotic; Animals; Catheterization; Cell Membrane; Cells, Cultu | 2001 |
Mechanism of hyperalgesia in SART stressed (repeated cold stress) mice: antinociceptive effect of neurotropin.
Topics: 5-Hydroxytryptophan; Animals; Cold Temperature; Drug Interactions; Fenclonine; Haloperidol; Hyperalg | 1991 |