5-hydroxytryptophan has been researched along with Alcoholism in 7 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tryptophan (Trp) metabolism and disposition in relation to alcohol and alcoholism are briefly reviewed." | 8.79 | Tryptophan metabolism and disposition in relation to alcohol and alcoholism. ( Badawy, AA, 1996) |
| "Tryptophan (Trp) metabolism and disposition in relation to alcohol and alcoholism are briefly reviewed." | 4.79 | Tryptophan metabolism and disposition in relation to alcohol and alcoholism. ( Badawy, AA, 1996) |
| "20 patients suffering from alcohol addictions starting a detoxification therapy have been included in a prospective, randomized, double blind study." | 2.76 | The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. ( Boben-Bardutzky, D; Hafner, M; Ihan, A; Jukić, T; Rojc, B, 2011) |
| "Alcoholism is a complex disorder involving, among others, the serotoninergic (5-HT) system, mainly regulated by 5-HT(1A) autoreceptors in the dorsal raphe nucleus." | 1.35 | Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. ( Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelaï, S | 1 |
| Renoir, T | 1 |
| Chouchana, L | 1 |
| Saurini, F | 1 |
| Hanoun, N | 1 |
| Hamon, M | 1 |
| Lanfumey, L | 1 |
| Jukić, T | 1 |
| Rojc, B | 1 |
| Boben-Bardutzky, D | 1 |
| Hafner, M | 1 |
| Ihan, A | 1 |
| Mena, MA | 1 |
| Herrera, E | 1 |
| Badawy, AA | 1 |
| George, DT | 1 |
| Lindquist, T | 1 |
| Rawlings, RR | 1 |
| Eckardt, MJ | 1 |
| Moss, H | 1 |
| Mathis, C | 1 |
| Martin, PR | 1 |
| Linnoila, M | 1 |
| Lee, MA | 1 |
| Meltzer, HY | 1 |
| Jofre de Breyer, IJ | 1 |
1 review available for 5-hydroxytryptophan and Alcoholism
| Article | Year |
|---|---|
Tryptophan metabolism and disposition in relation to alcohol and alcoholism.
Topics: 5-Hydroxytryptophan; Alcoholism; Animals; Ethanol; Humans; Liver; Mice; Mice, Inbred C57BL; Rats; Se | 1996 |
2 trials available for 5-hydroxytryptophan and Alcoholism
| Article | Year |
|---|---|
The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms.
Topics: 5-Hydroxytryptophan; Alcoholism; Bilirubin; CD4-Positive T-Lymphocytes; Dietary Supplements; Double- | 2011 |
Pharmacologic maintenance of abstinence in patients with alcoholism: no efficacy of 5-hydroxytryptophan or levodopa.
Topics: 5-Hydroxytryptophan; Adult; Alcoholism; Analysis of Variance; Carbidopa; Double-Blind Method; Drug T | 1992 |
4 other studies available for 5-hydroxytryptophan and Alcoholism
| Article | Year |
|---|---|
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bod | 2008 |
Monoamine metabolism in rat brain regions following long term alcohol treatment.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Alcoholism; Animals; Brain; Dihydroxyphenylalanine; Dopamine; | 1980 |
Neuroendocrine responses to serotonergic agents in alcoholics.
Topics: 5-Hydroxytryptophan; Adult; Alcoholism; Arousal; Brain; Growth Hormone; Hospitalization; Humans; Hyd | 1991 |
Influence of ethanol on the effects of D,L-p-chlorphenylalanine in vitro.
Topics: 5-Hydroxytryptophan; Alcoholism; Animals; Binding Sites; Binding, Competitive; Ethanol; Fenclonine; | 1973 |