5-hydroxytryptophan has been researched along with Aggression in 58 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") does not antagonize the reserpine hypothermia in mice and does not potentiate the 5-hydroxytryptophan head twitches in rats." | 3.70 | Repeated trimipramine induces dopamine D2/D3 and alpha1-adrenergic up-regulation. ( Maj, J; Margas, W; Rogóz, Z; Skuza, G, 1998) |
| "Mice maintained on a basal casein diet supplemented with 4% L-tyrosine potentiated L-DOPA effects on aggression." | 3.67 | Effects of drug-induced changes in brain monoamines on aggression and motor behavior in mice. ( Brown, JW; Kramarcy, NR; Thurmond, JB, 1984) |
| "In previous studies tryptophan and 5-hydroxy-tryptophan (5-HTP) treatments produced opposite effects on aggression and vigilance and differing effects on eating and locomoting in vervet monkeys." | 3.67 | Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems. ( Raleigh, MJ, 1987) |
| " 5-Hydroxytryptophan (100 mg/kg) administration elevated serotonin level to normal values and completely blocked predatory aggression." | 3.65 | [The role of serotonin in one of the types of aggressive behavior--"predatory aggression"]. ( Arav, VA; Kudriavtseva, NN; Nikulina, EM; Popova, NK, 1975) |
| "Thus amperozide is a potent antagonist of muricidal behaviour (ED50 = 0." | 1.28 | Amperozide and emotional behaviour. ( Christensson, E; Gustafsson, B, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (63.79) | 18.7374 |
| 1990's | 9 (15.52) | 18.2507 |
| 2000's | 7 (12.07) | 29.6817 |
| 2010's | 5 (8.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bubak, AN | 3 |
| Watt, MJ | 1 |
| Renner, KJ | 3 |
| Luman, AA | 1 |
| Costabile, JD | 1 |
| Sanders, EJ | 1 |
| Grace, JL | 1 |
| Swallow, JG | 3 |
| Dyakonova, VE | 1 |
| Krushinsky, AL | 1 |
| Yuan, Q | 1 |
| Song, Y | 1 |
| Yang, CH | 1 |
| Jan, LY | 1 |
| Jan, YN | 1 |
| Singh, GK | 1 |
| Garabadu, D | 1 |
| Muruganandam, AV | 1 |
| Joshi, VK | 1 |
| Krishnamurthy, S | 1 |
| Carrillo, M | 1 |
| Ricci, LA | 1 |
| Coppersmith, GA | 1 |
| Melloni, RH | 1 |
| Natarajan, D | 1 |
| de Boer, SF | 1 |
| Koolhaas, JM | 1 |
| Weinstock, M | 1 |
| Weiss, C | 1 |
| Miyamoto, M | 1 |
| Saji, Y | 1 |
| Nagawa, Y | 1 |
| Soulairac, A | 2 |
| Lambinet, H | 2 |
| Kramarcy, NR | 1 |
| Brown, JW | 1 |
| Thurmond, JB | 2 |
| Payne, AP | 1 |
| Andrews, MJ | 1 |
| Wilson, CA | 1 |
| Mogilnicka, E | 1 |
| Dooley, DJ | 1 |
| Boissard, CG | 1 |
| Delini-Stula, A | 1 |
| Carissimi, M | 1 |
| Picciòla, G | 1 |
| Ravenna, F | 1 |
| Carenini, G | 1 |
| Gentili, P | 1 |
| Miachon, S | 2 |
| Rochet, T | 1 |
| Mathian, B | 1 |
| Barbagli, B | 1 |
| Claustrat, B | 1 |
| Sánchez, C | 1 |
| Hyttel, J | 1 |
| Fachinelli, C | 2 |
| Ison, M | 1 |
| Rodríguez Echandía, EL | 2 |
| Maj, J | 3 |
| Rogóz, Z | 3 |
| Skuza, G | 1 |
| Margas, W | 1 |
| Dlaboga, D | 1 |
| Dziedzicka-Wasylewska, M | 1 |
| Chiavegatto, S | 1 |
| Dawson, VL | 1 |
| Mamounas, LA | 1 |
| Koliatsos, VE | 1 |
| Dawson, TM | 1 |
| Nelson, RJ | 1 |
| Augier, S | 1 |
| Jouvenet, M | 1 |
| Boucher, P | 1 |
| Vallon, JJ | 1 |
| Shishkina, GT | 1 |
| Dygalo, NN | 1 |
| Florvall, L | 1 |
| Ask, AL | 1 |
| Ogren, SO | 1 |
| Ross, SB | 1 |
| Trimble, M | 1 |
| Chadwick, D | 1 |
| Reynolds, EH | 1 |
| Marsden, CD | 1 |
| Popova, NK | 1 |
| Nikulina, EM | 1 |
| Arav, VA | 1 |
| Kudriavtseva, NN | 1 |
| Anand, M | 1 |
| Gupta, GP | 1 |
| Bhargava, KP | 1 |
| Malick, JB | 1 |
| Barnett, A | 1 |
| Gibbons, JL | 1 |
| Barr, GA | 1 |
| Bridger, WH | 1 |
| Leibowitz, SF | 1 |
| Beleslin, DB | 1 |
| Samardzić, R | 1 |
| Onodera, K | 1 |
| Kisara, K | 1 |
| Ogura, Y | 1 |
| Nyhan, WL | 2 |
| Yamamoto, T | 2 |
| Ueki, S | 2 |
| Aymard, N | 1 |
| Allikmets, LKh | 1 |
| Zharkovskiĭ, AM | 1 |
| Raleigh, MJ | 2 |
| McGuire, MT | 1 |
| Datla, KP | 1 |
| Mitra, SK | 1 |
| Bhattacharya, SK | 1 |
| Van Praag, HM | 3 |
| Asnis, GM | 2 |
| Kahn, RS | 1 |
| Brown, SL | 2 |
| Korn, M | 1 |
| Friedman, JM | 1 |
| Wetzler, S | 1 |
| Gustafsson, B | 1 |
| Christensson, E | 1 |
| López-Ibor, JJ | 1 |
| Saiz-Ruiz, J | 1 |
| Pérez de los Cobos, JC | 1 |
| Kahn, R | 1 |
| Lemus, CZ | 1 |
| Sargo, S | 1 |
| Bataller, R | 1 |
| Borsini, F | 1 |
| Volterra, G | 1 |
| Cutrufo, C | 1 |
| Furio, M | 1 |
| Meli, A | 1 |
| Ieni, JR | 1 |
| Watanabe, S | 1 |
| Kataoka, Y | 1 |
| Shibata, S | 1 |
| Shibata, K | 1 |
| Ohta, H | 1 |
| Shimazoe, T | 1 |
| Kawamoto, H | 1 |
| Senault, B | 1 |
| Papeschi, R | 1 |
| Kostowski, W | 1 |
| Tarchalska, B | 1 |
| Pankesepp, J | 1 |
| Zolovick, AJ | 1 |
| Jalowiec, JE | 1 |
| Stern, WC | 1 |
| Morgane, PJ | 1 |
| Kulkarni, AS | 3 |
| Rahwan, RG | 1 |
| Bocknik, SE | 2 |
| Di Chiara, G | 1 |
| Camba, R | 1 |
| Spano, PF | 1 |
| Randrup, A | 1 |
| Munkvad, I | 1 |
3 reviews available for 5-hydroxytryptophan and Aggression
| Article | Year |
|---|---|
The effect of increased serotonergic neurotransmission on aggression: a critical meta-analytical review of preclinical studies.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal | 2009 |
Nosological tunnel vision in biological psychiatry. A plea for a functional psychopathology.
Topics: 5-Hydroxytryptophan; Aggression; Biology; Depression; Depressive Disorder; Humans; Mental Disorders; | 1990 |
Affective disorders and aggression disorders: evidence for a common biological mechanism.
Topics: 5-Hydroxytryptophan; Aggression; Blood Platelets; Carrier Proteins; Celiac Disease; Depressive Disor | 1986 |
1 trial available for 5-hydroxytryptophan and Aggression
| Article | Year |
|---|---|
[Action of the serotonin precursor, 5-hydroxy-tryptophan, on aggressive symptomology].
Topics: 5-Hydroxytryptophan; Aggression; Clinical Trials as Topic; Humans; Mental Disorders; Placebos | 1976 |
54 other studies available for 5-hydroxytryptophan and Aggression
| Article | Year |
|---|---|
Sex differences in aggression: Differential roles of 5-HT2, neuropeptide F and tachykinin.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior Observation Techniques; Behavior, Animal; Diptera | 2019 |
Serotonin precursor (5-hydroxytryptophan) causes substantial changes in the fighting behavior of male crickets, Gryllus bimaculatus.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Gryllidae; Male; Motor Activity; Posture; Social Dominance | 2013 |
Whole brain monoamine detection and manipulation in a stalk-eyed fly.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Biogenic Monoamines; Brain Chemistry; Competitive Behavior | 2013 |
Heightened serotonin influences contest outcome and enhances expression of high-intensity aggressive behaviors.
Topics: 5-Hydroxytryptophan; Aggression; Agonistic Behavior; Animals; Antidepressive Agents, Second-Generati | 2014 |
Female contact modulates male aggression via a sexually dimorphic GABAergic circuit in Drosophila.
Topics: 5-Hydroxytryptophan; Aggression; Analysis of Variance; Animals; Animals, Genetically Modified; Brain | 2014 |
Antidepressant activity of Asparagus racemosus in rodent models.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Aggression; Animals; Antidepressive Agents; Antioxid | 2009 |
Lack of differential serotonin biosynthesis capacity in genetically selected low and high aggressive mice.
Topics: 5-Hydroxytryptophan; Aggression; Analysis of Variance; Animals; Behavior, Animal; Chromatography, Hi | 2009 |
Antagonism by propranolol of isolation-induced aggression in mice: correlation with 5-hydroxytryptamine receptor blockade.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Aggression; Animals; Behavior, Animal; Drug Intera | 1980 |
[Behavioral changes following lesioning of the nucleus accumbens (ACB) and effects of centrally acting drugs in rats (author's transl)].
Topics: 5-Hydroxytryptophan; Acetates; Aggression; Agonistic Behavior; Aminooxyacetic Acid; Animals; Anti-An | 1980 |
[Biological and pharmacological data on aggressive behavior (application to mental pathology].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Hormones; Humans; Mice; Neurotran | 1984 |
Effects of drug-induced changes in brain monoamines on aggression and motor behavior in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Biogenic Amin | 1984 |
Housing, fighting and biogenic amines in the midbrain and hypothalamus of the golden hamster.
Topics: 5-Hydroxytryptophan; Aggression; Agonistic Behavior; Animals; Biogenic Amines; Brain; Cricetinae; Ho | 1984 |
Facilitation of shock-induced fighting in the rat after DSP-4, a selective noradrenergic neurotoxin.
Topics: 5-Hydroxytryptophan; Aggression; Amines; Animals; Benzylamines; Drug Interactions; Electroshock; Hum | 1983 |
[2-(2-Thienyl)morpholines with CNS activity].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; | 1980 |
Long-term isolation of Wistar rats alters brain monoamine turnover, blood corticosterone, and ACTH.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aggression; Animals; Biogenic Monoamines; Brain; C | 1993 |
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis o | 1994 |
Effect of subchronic and chronic exposure to 5-hydroxytryptophan (5-HTP) on the aggressive behavior induced by food competition in undernourished dominant and submissive pigeons (Columba livia).
Topics: 5-Hydroxytryptophan; Aggression; Animals; Columbidae; Competitive Behavior; Dominance-Subordination; | 1996 |
Repeated trimipramine induces dopamine D2/D3 and alpha1-adrenergic up-regulation.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Antidepressive Agents, Tricyclic; Dopamine Agonists; Explo | 1998 |
Pharmacological effects of venlafaxine, a new antidepressant, given repeatedly, on the alpha 1-adrenergic, dopamine and serotonin systems.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Aggression; Amphetamine; Animals; Antidepressive Age | 1999 |
Pharmacological effects of milnacipran, a new antidepressant, given repeatedly on the alpha1-adrenergic and serotonergic 5-HT2A systems.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Aggression; Amphetamin | 2000 |
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Brain; Fenclonine; | 2001 |
Nutritional parameters modify muricidal behavior of male Wistar rats: preventive effects of amino acids and 4' Cl diazepam.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Benzodiazepinones; Cholesterol; Diet; Di | 2001 |
Role of the serotoninergic system in the acceleration of sexual maturation in wild Norway rats selected for reduced aggressiveness toward humans.
Topics: 5-Hydroxytryptophan; Aggression; Aging; Animals; Epididymis; Female; Fenclonine; Humans; Hypothalamu | 2000 |
Selective monoamine oxidase inhibitors. 1. Compounds related to 4-aminophenethylamine.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Central Nervous System; Central N | 1978 |
Letter: L 5-Hydroxytryptophan and mood.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Aggression; Brain Neoplasms; Depression; Dose-Response Rela | 1975 |
[The role of serotonin in one of the types of aggressive behavior--"predatory aggression"].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Brain Chemistry; Fenclonine; Humans; Male; Mesencephalon; | 1975 |
Effect of tryptaminergic drugs on electroshock fighting behaviour in rats.
Topics: 5-Hydroxytryptophan; Aggression; Agonistic Behavior; Animals; Brain Chemistry; Electroshock; Fenclon | 1976 |
The role of serotonergic pathways in isolation-induced aggression in mice.
Topics: 5-Hydroxytryptophan; Aggression; Amidines; Animals; Cinanserin; Cyproheptadine; Depression, Chemical | 1976 |
Effects of para-chlorophenylalanine and 5-hydroxytryptophan on mouse killing behavior in killer rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Body Weight; Brain; Dose-Response Relati | 1978 |
Effects of parachlorophenylalanine and 5,6-dihydroxytryptamine on aggressive behaviour evoked by cholinomimetics and anticholinesterases injected into the cerebral ventricles of conscious cats.
Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Aggression; Animals; Cats; Cholinesterase Inhibitors; | 1979 |
Effect of 5-hydroxytryptophan on muricide response induced by thiamine deficiency.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Benserazide; Drug Interactions; Fenclonine; Humans; Male; | 1979 |
The Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Adolescent; Aggression; Allopurinol; Behavior Therapy; Child; Child Behavior Di | 1978 |
Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Atropine; Brain Stem; Clomipramine; Desipramine; Humans; I | 1978 |
[The influence of 1-DOPA on emotional responses and serotonin metabolism in the rat brain].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Brain; Dopamine; Emotions; Exploratory Behavior; Humans; H | 1976 |
Behavior in the Lesch--Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Aggression; Behavior Therapy; Carbidopa; Carboxy-Lyases; Compulsive Behavior; D | 1976 |
Bidirectional relationships between tryptophan and social behavior in vervet monkeys.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Awareness; Chlorocebus aethiops; Female; Fluoxetine; Locom | 1991 |
Serotonergic modulation of footshock induced aggression in paired rats.
Topics: 5-Hydroxytryptophan; Aggression; Agonistic Behavior; Animals; Apomorphine; Citalopram; Clorgyline; D | 1991 |
Amperozide and emotional behaviour.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Blepharoptosis; Conflict, Psychological; | 1990 |
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas | 1985 |
Therapeutic indications for serotonin-potentiating compounds: a hypothesis.
Topics: 5-Hydroxytryptophan; Aggression; Antidepressive Agents; Anxiety; Brain; Depressive Disorder; Desipra | 1987 |
Effect of 5-HTP and ketanserine on the aggressive reaction induced by food competition in dominant and submissive pigeons (Columba livia).
Topics: 5-Hydroxytryptophan; Aggression; Animals; Columbidae; Feeding Behavior; Ketanserin; Serotonin | 1989 |
Pharmacological profile of the new anticonvulsant etazepine.
Topics: 5-Hydroxytryptophan; Aggression; Analgesics; Animals; Anticonvulsants; Dibenzazepines; Eating; Male; | 1989 |
Differential behavioral effects of tryptophan and 5-hydroxytryptophan in vervet monkeys: influence of catecholaminergic systems.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Arousal; Behavior, Animal; Brain; Chlorocebus aethiops; De | 1987 |
Maternal aggression in mice: effects of treatments with PCPA, 5-HTP and 5-HT receptor antagonists.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Biogenic Amines; Brain Chemistry; Female; Fenclonine; Huma | 1985 |
Behavioral and electroencephalographic effects of zopiclone, a cyclopyrrolone derivative.
Topics: 5-Hydroxytryptophan; Aggression; Anesthesia; Animals; Azabicyclo Compounds; Behavior, Animal; Confli | 1987 |
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clon | 1974 |
An investigation on the behavioral and hypothermic effects of yohimbine: interaction with drugs affecting central and peripheral monoamines.
Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Bens | 1974 |
The effects of some drugs affecting brain 5-HT on the aggressive behaviour and spontaneous electrical activity of the central nervous system of the ant, Formica rufa.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Ants; Behavior, Animal; Central Nervous System; Electroenc | 1972 |
Fenfluramine: effects on aggression.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Cats; Cortical Synchronization; Electric Stimulation; Elec | 1973 |
Muricidal block induced by 5-hydroxytryptophan in the rat.
Topics: 5-Hydroxytryptophan; Aggression; Amygdala; Animals; Avoidance Learning; Behavior, Animal; Benserazid | 1973 |
Effect of a decarboxylase inhibitor (Ro 4-4602) on 5-HTP induced muricide blockade in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, An | 1974 |
Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Humans; Injections, Intraperitone | 1971 |
DOPA and other naturally occurring substances as causes of stereotypy and rage in rats.
Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Behavior, Animal; Dihydroxyphenylalanine; Hum | 1966 |
Muricidal block produced by 5-hydroxytryptophan and various drugs.
Topics: 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Desi | 1968 |