Excerpt | Relevance | Reference |
"5-hydroxytryptophan is an important metabolite in the serotonin synthetic pathway, the key pathway in determining somnolence, thus offering a possible link to the eponymous symptoms of "sleeping sickness"." | 1.43 | Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis. ( Barrett, MP; Biéler, S; Bisser, S; Cattanach, AM; Courtioux, B; Daly, R; Ndung'u, JM; Vincent, IM, 2016) |
"Neopterin is an inflammatory biomarker previously shown in CSF of stage 2 but not stage 1 patients." | 1.43 | Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis. ( Barrett, MP; Biéler, S; Bisser, S; Cattanach, AM; Courtioux, B; Daly, R; Ndung'u, JM; Vincent, IM, 2016) |
"Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the blood-brain barrier in the cerebrospinal fluid (CSF))." | 1.43 | Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis. ( Barrett, MP; Biéler, S; Bisser, S; Cattanach, AM; Courtioux, B; Daly, R; Ndung'u, JM; Vincent, IM, 2016) |