5-hydroxytryptophan has been researched along with Ache in 30 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-Tryptophan (L-TP) has been used in migraine and other pain conditions." | 5.27 | Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis. ( Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G, 1986) |
| "The reduction of ECS-induced retrograde amnesia observed in 5,7-DHT, MRN-lesioned rats was considered as due to a lower synaptic availability of 5-HT at the time of ECS administration." | 5.26 | Reduction of ECS-induced retrograde amnesia of passive avoidance conditioning after 5,7-dihydroxytryptamine median raphe nucleus lesion in the rat. ( Dall'Olio, R; Gandolfi, O; Montanaro, N, 1981) |
| " Parachlorophenylalanine chronic administration in migraine-headache sufferers lowered the pain threshold so far as to provoke (in 20% of cases) spontaneous pains in the trunk, legs and arms." | 5.25 | 5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine. ( Anselmi, B; Del Bene, E; Galli, P; Sicuteri, F, 1975) |
| "5-Hydroxytryptophan (5HTP) was injected subcutaneously into awake female rats to induce VH; the 5HT3 antagonist (granisetron) or saline (control) were injected 30 minutes later." | 1.35 | Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats. ( Chang, FY; Dun, NJ; Hsieh, JC; Lee, SD; Lin, HC; Lu, CL; Luo, JC; Oprea, TI; Wang, PS, 2009) |
| "L-Tryptophan (L-TP) has been used in migraine and other pain conditions." | 1.27 | Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis. ( Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G, 1986) |
| "The reduction of ECS-induced retrograde amnesia observed in 5,7-DHT, MRN-lesioned rats was considered as due to a lower synaptic availability of 5-HT at the time of ECS administration." | 1.26 | Reduction of ECS-induced retrograde amnesia of passive avoidance conditioning after 5,7-dihydroxytryptamine median raphe nucleus lesion in the rat. ( Dall'Olio, R; Gandolfi, O; Montanaro, N, 1981) |
| "Four approaches were used to alter transmission in monoamine pathways." | 1.25 | Monoaminergic mechanisms of stimulation-produced analgesia. ( Akil, H; Liebeskind, JC, 1975) |
| " Parachlorophenylalanine chronic administration in migraine-headache sufferers lowered the pain threshold so far as to provoke (in 20% of cases) spontaneous pains in the trunk, legs and arms." | 1.25 | 5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine. ( Anselmi, B; Del Bene, E; Galli, P; Sicuteri, F, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (80.00) | 18.7374 |
| 1990's | 4 (13.33) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, CL | 1 |
| Hsieh, JC | 1 |
| Dun, NJ | 1 |
| Oprea, TI | 1 |
| Wang, PS | 1 |
| Luo, JC | 1 |
| Lin, HC | 1 |
| Chang, FY | 1 |
| Lee, SD | 1 |
| Montanaro, N | 1 |
| Dall'Olio, R | 1 |
| Gandolfi, O | 1 |
| Besson, JM | 2 |
| Oliveras, JL | 1 |
| Chaouch, A | 1 |
| Rivot, JP | 1 |
| Kraus, E | 1 |
| Le Bars, D | 2 |
| Chitour, D | 1 |
| Dickenson, AH | 1 |
| Ramabadran, K | 1 |
| Jacob, JJ | 1 |
| Harvey, JA | 4 |
| Simansky, KJ | 1 |
| Weil-Fugazza, J | 1 |
| Godefroy, F | 1 |
| Savchenko, AB | 1 |
| Lebedev, VP | 1 |
| Nozdrachev, AD | 1 |
| Nicolodi, M | 1 |
| Sicuteri, F | 2 |
| Coelho, AM | 1 |
| Jacob, L | 1 |
| Fioramonti, J | 1 |
| Bueno, L | 1 |
| Akil, H | 1 |
| Liebeskind, JC | 1 |
| Schlosberg, AJ | 1 |
| Yunger, LM | 2 |
| Anselmi, B | 1 |
| Del Bene, E | 1 |
| Galli, P | 1 |
| Tamir, H | 2 |
| Karpiak, SE | 1 |
| Wajda, IJ | 1 |
| Wilchek, M | 2 |
| Bodner, RJ | 1 |
| Sarzi Puttini, P | 1 |
| Caruso, I | 1 |
| Steinman, JL | 1 |
| Carlton, SM | 1 |
| Haber, B | 1 |
| Willis, WD | 1 |
| Genazzani, AR | 1 |
| Sandrini, G | 1 |
| Facchinetti, F | 1 |
| Rizzo, V | 1 |
| Alfonsi, E | 1 |
| Sances, G | 1 |
| Calvani, M | 1 |
| Nappi, G | 1 |
| Uldry, PA | 1 |
| Regli, F | 1 |
| Eide, PK | 1 |
| Hole, K | 1 |
| Berge, OG | 1 |
| Broch, OJ | 1 |
| Tsai, CF | 1 |
| Lin, MT | 1 |
| Panerai, AE | 1 |
| Post, C | 1 |
| Minor, BG | 1 |
| Davies, M | 1 |
| Archer, T | 1 |
| Emmers, R | 1 |
| Contreras, E | 1 |
| Quijada, L | 1 |
| Tamayo, L | 1 |
| Reinhold, K | 1 |
| Bläsig, J | 1 |
| Herz, A | 1 |
| Lints, CE | 1 |
| White, SR | 1 |
| White, FP | 1 |
| Barnes, CD | 1 |
| Albright, JF | 1 |
| Coscina, DV | 1 |
| Balagura, S | 1 |
3 reviews available for 5-hydroxytryptophan and Ache
| Article | Year |
|---|---|
The role of serotonin in modulation of nociceptive reflexes.
Topics: 5-Hydroxytryptophan; Animals; Brain; Diet; Hydroxydopamines; Monoamine Oxidase Inhibitors; Neurotoxi | 1981 |
Behavioral correlates of serotonin depletion.
Topics: 5-Hydroxytryptophan; Acetylcholine; Amygdala; Animals; Behavior, Animal; Brain; Dihydroxyphenylalani | 1975 |
[Indications for L-5-hydroxytryptophan in neurology].
Topics: 5-Hydroxytryptophan; Down Syndrome; Epilepsy; Humans; Migraine Disorders; Myoclonus; Pain; Parkinson | 1987 |
1 trial available for 5-hydroxytryptophan and Ache
| Article | Year |
|---|---|
L-5-hydroxytryptophan can prevent nociceptive disorders in man.
Topics: 5-Hydroxytryptophan; Analgesics; Ascorbic Acid; Child; Child, Preschool; Female; Follow-Up Studies; | 1999 |
26 other studies available for 5-hydroxytryptophan and Ache
| Article | Year |
|---|---|
Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats.
Topics: 5-Hydroxytryptophan; Abdominal Muscles; Animals; Calcitonin Gene-Related Peptide; Electromyography; | 2009 |
Reduction of ECS-induced retrograde amnesia of passive avoidance conditioning after 5,7-dihydroxytryptamine median raphe nucleus lesion in the rat.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Amnesia; Amnesia, Retrograde; Animals; Avoidance Learn | 1981 |
Role of the raphe nuclei in stimulation producing analgesia.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Brain Stem; Cats; Dental Pulp; Electric Stimulation; Neuron | 1981 |
Behavioral model for diffuse noxious inhibitory controls (DNIC): potentiation by 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Benzoquinones; Cinanserin; Cinnamates; Drug Synergism; Electric Stimul | 1982 |
Pharmacological evidence for the involvement of serotonergic mechanisms in diffuse noxious inhibitory controls (DNIC).
Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Cinanserin; Male; Metergoline; Neural Inhibition; Neural P | 1982 |
Effects of various serotoninergic agonists and an antagonist on a nociceptive reaction in mice.
Topics: 5-Hydroxytryptophan; Animals; Cyproheptadine; Enkephalins; Male; Mice; Mice, Inbred Strains; Nocicep | 1982 |
Dorsal and ventral dopaminergic innervation of the spinal cord: functional implications.
Topics: 5-Hydroxytryptophan; Animals; Arthritis, Experimental; Behavior, Animal; Dopamine; Lumbosacral Regio | 1993 |
[Modulation of transcranial electroanalgesia by effecting the serotoninergic system of the brain].
Topics: 5-Hydroxytryptophan; Allopurinol; Animals; Brain; Enzyme Inhibitors; Nialamide; Pain; Rats; Rats, Wi | 1996 |
Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype.
Topics: 5-Hydroxytryptophan; Analgesics, Non-Narcotic; Animals; Catheterization; Cell Membrane; Cells, Cultu | 2001 |
Monoaminergic mechanisms of stimulation-produced analgesia.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Apomorphine; Brain; Cerebral Aqueduct; Disulfiram; Dopamine | 1975 |
5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine.
Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Headache; Humans; Pain; Serotonin; Tryptophan | 1975 |
Analgesic effects of N-acetyl-5HTP-5HTP amide are not directly related to brain serotonin levels.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Brain Chemistry; Male; Naloxone; Pain; Rats; Reaction Time | 1979 |
Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study.
Topics: 5-Hydroxytryptophan; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Time Factors | 1992 |
Differential effects of p-chlorophenylalanine on indoleamines in brainstem nuclei and spinal cord of rats. I. Biochemical and behavioral analysis.
Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Female; Fenclonine; Hydroxyindoleacetic Acid; Organ Specif | 1987 |
Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis.
Topics: 5-Hydroxytryptophan; Adult; beta-Endorphin; Carbidopa; Drug Therapy, Combination; Endorphins; Humans | 1986 |
5-HT depletion with 5,7-DHT, PCA and PCPA in mice: differential effects on the sensitivity to 5-MeODMT, 8-OH-DPAT and 5-HTP as measured by two nociceptive tests.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; | 1988 |
Pain sensitivity, thermal capability, and brain monoamine turnover in hypertensive rats.
Topics: 5-Hydroxytryptophan; Amines; Animals; Body Temperature Regulation; Brain; Dihydroxyphenylalanine; Hy | 1987 |
[Potentiation concept in pharmacology].
Topics: 5-Hydroxytryptophan; Animals; Baclofen; Clomipramine; Diazepam; Drug Synergism; Drug Therapy, Combin | 1988 |
Analgesia induced by 5-hydroxytryptamine receptor agonists is blocked or reversed by noradrenaline-depletion in rats.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Central Nervous System; Male; Methoxydimethyltryptamines; | 1986 |
Influence of a serotonin receptor antagonist, 5-HTP-DP-hex, on spinal and thalamic nociceptive neurons in rats.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Ketanserin; Male; Methysergide; Naloxone; Nerve Fib | 1987 |
A comparative study of the effects of reserpine and p-chlorophenylalanine on morphine analgesia in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Dihydroxyphenylalanine; Drug Synergism; Fenclonine; Male; M | 1973 |
Effect of lesions in the medial forebrain bundle on three measures of pain sensitivity and noise-elicited startle.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Avoidance Learning; Brain Chemistry; Electroshoc | 1973 |
Changes in brain concentration of biogenic amines and the antinociceptive effect of morphine in rats.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Catecholamines; Dopamine; Dopamine beta-Hydrox | 1973 |
Lesions in the medial forebrain bundle: relationship between pain sensitivity and telencephalic content of serotonin.
Topics: 5-Hydroxytryptophan; Animals; Body Weight; Brain; Brain Chemistry; Brain Stem; Electroshock; Escape | 1971 |
Increased shock sensitivity in rats with experimental allergic encephalomyelitis and reversal by 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Electroshock; Encephalomyelitis, Autoimmune, Experimental; Pain; Rats; | 1973 |
Avoidance and escape behavior of rats with aphagia produced by basal diencephalic lesions.
Topics: 5-Hydroxytryptophan; Animal Nutritional Physiological Phenomena; Animals; Avoidance Learning; Behavi | 1970 |