5-hydroxytryptophan has been researched along with Abdominal Migraine in 24 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Interictal serum levels of serotonin and plasma and mononuclear cell concentrations of beta-endorphin were measured in 20 juvenile patients (13 suffering from migraine without aura and 7 from episodic tension-type headache) before and after 3 months of L-5-hydroxytryptophan treatment (5 mg/kg/day) and compared with a control group of 17 headache-free healthy subjects." | 9.08 | beta-endorphin in plasma and monocytes in juvenile headache. ( Battistella, PA; Bordin, A; Broetto, S; Cernetti, R; Corrà, S; Piva, E; Plebani, M, 1996) |
| "L-Tryptophan (L-TP) has been used in migraine and other pain conditions." | 5.27 | Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis. ( Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G, 1986) |
| "Interictal serum levels of serotonin and plasma and mononuclear cell concentrations of beta-endorphin were measured in 20 juvenile patients (13 suffering from migraine without aura and 7 from episodic tension-type headache) before and after 3 months of L-5-hydroxytryptophan treatment (5 mg/kg/day) and compared with a control group of 17 headache-free healthy subjects." | 5.08 | beta-endorphin in plasma and monocytes in juvenile headache. ( Battistella, PA; Bordin, A; Broetto, S; Cernetti, R; Corrà, S; Piva, E; Plebani, M, 1996) |
| "In this study fibromyalgia sufferers were randomly administered a combination of monoamine-oxidase inhibitors (MAOIs)-A/B with 5-HTP, 5-HTP alone, MAOIs-A/B alone, or the tricyclic drug amitriptyline in order to compare the efficacy of these treatments." | 5.08 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "The recently shown high prevalence of migraine in the population of fibromyalgia sufferers, suggests a common ground shared by fibromyalgia and migraine." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "Migraine has been demonstrated to be characterized by a defect in the serotonergic and adrenergic systems." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "One hundred and twenty-four migraineurs were treated randomly with 5-hydroxytryptophan (5-HTP) or with methysergide (M)." | 2.66 | 5-Hydroxytryptophan versus methysergide in the prophylaxis of migraine. Randomized clinical trial. ( Alom, J; Codina, A; Dávalos, A; Titus, F, 1986) |
| "Anti-migraine effect of Calotropis gigantea freeze-dried latex by inhibition of dopamine and serotonin receptors (D1 and D2: dopamine receptors; 5-HT: serotonin receptors); yellow color represents serotonergic, and blue color indicates dopaminergic neurons." | 1.72 | Anti-migraine activity of freeze-dried latex obtained from Calotropis gigantea Linn. ( Al-Harrasi, A; Aleya, L; Anwer, MK; Behl, T; Bhatia, S; Chigurupati, S; Kabir, MT; Kaushik, D; Kumar, A; Mittal, V; Sehgal, A; Sharma, N; Sharma, PB; Singh, S; Vargas-de-la-Cruz, C, 2022) |
| "To evaluate the analgesic and anti-migraine activities of senkyunolide I from Ligusticum chuanxiong." | 1.37 | Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. ( Feng, Y; He, CY; Hong, YL; Liang, S; Lin, X; Wang, YH; Xu, DS, 2011) |
| "chuanxiong, traditionally used to treat migraine." | 1.37 | Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. ( Feng, Y; He, CY; Hong, YL; Liang, S; Lin, X; Wang, YH; Xu, DS, 2011) |
| "Between attacks, migraineurs had lower plasma 5-HT and higher 5-HIAA levels than did healthy controls and patients with tension headache." | 1.28 | Serotonin metabolism in migraine. ( Bruyn, GW; Ferrari, MD; Odink, J; Pennings, EJ; Tapparelli, C; Van Kempen, GM, 1989) |
| "In thirty patients with common migraine the platelet concentrations of met-enkephalin immunoreactivity (ME) (76 +/- 9 pg/mg protein) were similar to those in 23 healthy volunteers (77 +/- 5), suggesting that there is no alteration in the ME pool in this biochemical compartment in migraine." | 1.27 | Platelet met-enkephalin immunoreactivity and 5-hydroxytryptamine concentrations in migraine patients: effects of 5-hydroxytryptophan, amitriptyline and chlorimipramine treatment. ( Boiardi, A; Bussone, G; Di Giulio, AM; Galva, MD; La Mantia, L; Mantegazza, P; Picotti, GB, 1984) |
| "L-Tryptophan (L-TP) has been used in migraine and other pain conditions." | 1.27 | Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis. ( Alfonsi, E; Calvani, M; Facchinetti, F; Genazzani, AR; Nappi, G; Rizzo, V; Sances, G; Sandrini, G, 1986) |
| "In fourteen untreated migraine patients with a mean age of 40 years platelet sensitivity to 5HT, EN and ADP was investigated during the prodromal phase (three patients), 12-48 h after headache (three patients) and during the headache-free period (eight patients)." | 1.27 | Evidence of enhanced platelet aggregation and platelet sensitivity in migraine patients. ( Fazekas, F; Lechner, H; Ott, E; Pilger, E, 1985) |
| "The vascular mechanism of migraine attacks--intracranial vasoconstriction during the prodromal stage and passive vasodilatation of extracranial arteries during the painful phase--has been confirmed by modern methods." | 1.26 | [Importance of chemical mediators for the pathogenesis and treatment of hemicrania]. ( Berde, B; Fanchamps, A, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (66.67) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatia, S | 1 |
| Al-Harrasi, A | 1 |
| Kumar, A | 1 |
| Behl, T | 1 |
| Sehgal, A | 1 |
| Singh, S | 1 |
| Sharma, N | 1 |
| Anwer, MK | 1 |
| Kaushik, D | 1 |
| Mittal, V | 1 |
| Chigurupati, S | 1 |
| Sharma, PB | 1 |
| Aleya, L | 1 |
| Vargas-de-la-Cruz, C | 1 |
| Kabir, MT | 1 |
| Wang, YH | 1 |
| Liang, S | 1 |
| Xu, DS | 1 |
| Lin, X | 1 |
| He, CY | 1 |
| Feng, Y | 1 |
| Hong, YL | 1 |
| Nagata, E | 1 |
| Shibata, M | 1 |
| Hamada, J | 1 |
| Shimizu, T | 1 |
| Katoh, Y | 1 |
| Gotoh, K | 1 |
| Suzuki, N | 1 |
| Boiardi, A | 2 |
| Crenna, P | 1 |
| Merati, B | 1 |
| Negri, S | 1 |
| Tansini, E | 1 |
| Bussone, G | 2 |
| Picotti, GB | 1 |
| Di Giulio, AM | 1 |
| Galva, MD | 1 |
| La Mantia, L | 1 |
| Mantegazza, P | 1 |
| Bono, G | 1 |
| Criscuoli, M | 1 |
| Martignoni, E | 1 |
| Salmon, S | 1 |
| Nappi, G | 2 |
| Battistella, PA | 1 |
| Bordin, A | 1 |
| Cernetti, R | 1 |
| Broetto, S | 1 |
| Corrà, S | 1 |
| Piva, E | 1 |
| Plebani, M | 1 |
| Nicolodi, M | 2 |
| Sicuteri, F | 4 |
| Lombardi, D | 1 |
| Merusi, I | 1 |
| Bottone, U | 1 |
| Del Bene, E | 1 |
| Fonda, C | 1 |
| Rivas Nuñez, CJ | 1 |
| Fernandez Martin, F | 1 |
| Fanciullacci, M | 1 |
| Franchi, G | 1 |
| Galli, P | 1 |
| Berde, B | 1 |
| Fanchamps, A | 1 |
| Maissen, CP | 1 |
| Ludin, HP | 1 |
| Ferrari, MD | 1 |
| Odink, J | 1 |
| Tapparelli, C | 1 |
| Van Kempen, GM | 1 |
| Pennings, EJ | 1 |
| Bruyn, GW | 1 |
| Welch, KM | 1 |
| Helpern, JA | 1 |
| Ewing, JR | 1 |
| Robertson, WM | 1 |
| D'Andrea, G | 1 |
| Genazzani, AR | 1 |
| Sandrini, G | 1 |
| Facchinetti, F | 1 |
| Rizzo, V | 1 |
| Alfonsi, E | 1 |
| Sances, G | 1 |
| Calvani, M | 1 |
| Uldry, PA | 1 |
| Regli, F | 1 |
| Lechner, H | 1 |
| Ott, E | 1 |
| Fazekas, F | 1 |
| Pilger, E | 1 |
| Curatolo, P | 1 |
| Sciarretta, A | 1 |
| Titus, F | 1 |
| Dávalos, A | 1 |
| Alom, J | 1 |
| Codina, A | 1 |
| Cahen, RL | 1 |
3 reviews available for 5-hydroxytryptophan and Abdominal Migraine
| Article | Year |
|---|---|
Sex, migraine and serotonin interrelationships.
Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Headache; Humans; Male; Menstruation; Migraine Dis | 1976 |
[Biochemical aspects of migraine].
Topics: 5-Hydroxytryptophan; Age Factors; Ammonia; Blood Platelet Disorders; Female; Humans; Menstruation; M | 1975 |
[Indications for L-5-hydroxytryptophan in neurology].
Topics: 5-Hydroxytryptophan; Down Syndrome; Epilepsy; Humans; Migraine Disorders; Myoclonus; Pain; Parkinson | 1987 |
6 trials available for 5-hydroxytryptophan and Abdominal Migraine
| Article | Year |
|---|---|
Serotonin precursors in migraine prophylaxis.
Topics: 5-Hydroxytryptophan; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kinetics; | 1982 |
beta-endorphin in plasma and monocytes in juvenile headache.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; beta-Endorphin; Child; Female; Headache; Humans; Male; Migra | 1996 |
Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy.
Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Drug Therapy, Combina | 1996 |
L-5-hydroxytryptophan can prevent nociceptive disorders in man.
Topics: 5-Hydroxytryptophan; Analgesics; Ascorbic Acid; Child; Child, Preschool; Female; Follow-Up Studies; | 1999 |
[Comparison of the effect of 5-hydroxytryptophan and propranolol in the interval treatment of migraine].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Double-Blind Method; Humans; Middle Aged; Migraine Dis | 1991 |
5-Hydroxytryptophan versus methysergide in the prophylaxis of migraine. Randomized clinical trial.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Child; Clinical Trials as Topic; Female; Humans; Male; Methy | 1986 |
15 other studies available for 5-hydroxytryptophan and Abdominal Migraine
| Article | Year |
|---|---|
Anti-migraine activity of freeze-dried latex obtained from Calotropis gigantea Linn.
Topics: 5-Hydroxytryptophan; Apomorphine; Calotropis; Dizocilpine Maleate; Latex; Migraine Disorders; Phenol | 2022 |
Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong.
Topics: 5-Hydroxytryptophan; Acetates; Analgesics; Animals; Benzofurans; Brain; Dopamine; Drugs, Chinese Her | 2011 |
Plasma 5-hydroxytryptamine (5-HT) in migraine during an attack-free period.
Topics: 5-Hydroxytryptophan; Adult; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleaceti | 2006 |
5-OH-Tryptophane in migraine: clinical and neurophysiological considerations.
Topics: 5-Hydroxytryptophan; Adult; Aspirin; Female; Humans; Male; Middle Aged; Migraine Disorders; Nocicept | 1981 |
Platelet met-enkephalin immunoreactivity and 5-hydroxytryptamine concentrations in migraine patients: effects of 5-hydroxytryptophan, amitriptyline and chlorimipramine treatment.
Topics: 5-Hydroxytryptophan; Adult; Amitriptyline; Blood Platelets; Clomipramine; Enkephalin, Methionine; Fe | 1984 |
[Vertigo in adolescents with hemicrania].
Topics: 5-Hydroxytryptophan; Adolescent; Age Factors; Antidepressive Agents; Female; Flunarizine; Humans; Ma | 2001 |
[Progress of clinical pharmacology in essential headaches].
Topics: 5-Hydroxytryptophan; Brain; Ergotamine; Headache; Humans; Methysergide; Migraine Disorders; Serotoni | 1976 |
[Importance of chemical mediators for the pathogenesis and treatment of hemicrania].
Topics: 5-Hydroxytryptophan; Aminopyrine; Female; Histamine; Humans; Kinins; Lysergic Acid Diethylamide; Men | 1976 |
Serotonin metabolism in migraine.
Topics: 5-Hydroxytryptophan; Headache; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Monoamine Oxida | 1989 |
Biochemical effects of cerebral ischemia: relevance to migraine.
Topics: 5-Hydroxytryptophan; Brain; Brain Ischemia; Catecholamines; Energy Metabolism; Humans; Magnetic Reso | 1985 |
Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis.
Topics: 5-Hydroxytryptophan; Adult; beta-Endorphin; Carbidopa; Drug Therapy, Combination; Endorphins; Humans | 1986 |
Evidence of enhanced platelet aggregation and platelet sensitivity in migraine patients.
Topics: 5-Hydroxytryptophan; Adenosine Diphosphate; Adolescent; Adult; beta-Thromboglobulin; Epinephrine; Hu | 1985 |
Benign paroxysmal vertigo and migraine.
Topics: 5-Hydroxytryptophan; Child; Child, Preschool; Humans; Migraine Disorders; Vertigo | 1987 |
Emetic effect of biogenic amines.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain; Catecholamines; | 1970 |
The ingestion of serotonin precursors (L-5-hydroxytryptophan and L-tryptophan) improves migraine headache.
Topics: 5-Hydroxytryptophan; Humans; Methysergide; Migraine Disorders; Tryptophan | 1973 |