Compounds > 5-hydroxymethylcytosine
Page last updated: 2024-08-25

5-hydroxymethylcytosine and Pregnancy

5-hydroxymethylcytosine has been researched along with Pregnancy in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's23 (85.19)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Alisch, RS; Chen, K; Keleş, S; Madrid, A; Papale, LA; Sak, L; Zhang, Q1
Fang, Q; Zhang, Y; Zheng, D; Zhong, M1
Gibas, P; Gordevičius, J; Kriukienė, E; Krjutškov, K; Kvederavičiūtė, K; Narmontė, M; Paluoja, P; Salumets, A; Tomkutė, V1
Baranov, VS; Chiryaeva, OG; Dudkina, VS; Efimova, OA; Krapivin, MI; Pendina, AA; Petrova, LI; Smirnova, AA; Talantova, OE; Tikhonov, AV1
Öztürk, H; Öztürk, NC; Resendiz, M; Zhou, FC1
Esteller, M; Hernandez Mora, JR; Iglesias-Platas, I; Monk, D; Moran, S; Petazzi, P; Sanchez-Delgado, M1
Liu, L; Mitsuya, K; Myatt, L; Parker, AN; Ruan, J; Vissers, MCM1
Bogo, MR; Crippa, JAS; da Silva, VK; de Freitas, BS; Dornelles, VC; Hallak, JE; Kist, LW; Schröder, N; Silva, MC; Streck, EL; Zuardi, AW1
Deng, R; Han, C; Liu, J; Luo, Y; Mao, T; Meng, P; Quan, F; Wei, B; Zhang, Q; Zhang, Y; Zhao, L1
Chen, SL; Chen, X; Chen, XL; Liu, YD; Lu, S; Wu, AH; Yang, DY1
Chen, D; Jin, J; Li, X; Liu, A; Luo, Z; Wu, Y; Xie, F; Zhang, F; Zhang, S1
Bjork, F; Harris, SM; Hassan, I; Kumar, A; Lash, LH; Loch-Caruso, R1
Baranov, VS; Efimova, OA; Glotov, OS; Kopat, VV; Krapivin, MI; Navodnikova, PM; Pendina, AA; Petrovskaia-Kaminskaia, AV; Talantova, OE; Tikhonov, AV1
Cao, Z; Chen, Z; Gao, D; Khan, IM; Luo, L; Tong, X; Wang, Y; Xu, T; Zhang, D; Zhang, L; Zhang, M; Zhang, Y1
Buchholz, F; Calegari, F; Noack, F; Pataskar, A; Schneider, M; Tiwari, VK1
Bianco-Miotto, T; François, M; Jankovic-Karasoulos, T; Leifert, WR; McAninch, D; McCullough, D; Roberts, CT; Wilson, RL1
Huang, Y; Jin, L; Lin, S; Ren, A; Wang, L1
Doria, S; Marques, CJ; Ramalho, C; Vasconcelos, S1
Chen, Y; Oztürk, NC; Resendiz, M; Zhou, FC1
Das, SK; Gao, F1
Drake, AJ; Khulan, B; Menon, G; Piyasena, C; Reynolds, RM; Seckl, JR1
Cheng, H; Kong, L; Lan, F; Li, X; Lv, R; Zhu, L1
Chen, J; Chen, L; Dai, Q; Gao, Q; He, C; Jin, P; Li, L; Lin, L; Song, MM; Sun, M; Tao, J; Wei, B; Xu, Z; Yao, B; Zhou, X1
Devlieger, R; Duca, RC; Freson, K; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Straetmans, D; Van Herck, E1
Hemberger, M1
Rugg-Gunn, PJ1
Chouliaras, L; Delbroek, L; Prickaerts, J; Rostamian, S; Rutten, BP; Sierksma, AS; Steinbusch, HW; van den Hove, DL1

Reviews

4 review(s) available for 5-hydroxymethylcytosine and Pregnancy

ArticleYear
Epigenetic medicine and fetal alcohol spectrum disorders.
    Epigenomics, 2013, Volume: 5, Issue:1

    Topics: 5-Methylcytosine; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Gene Expression Regulation; Histones; Humans; Pregnancy

2013
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
    Biomolecular concepts, 2014, Volume: 5, Issue:2

    Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Decidua; DNA Methylation; Embryo Implantation; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Humans; Pregnancy; Protein Processing, Post-Translational

2014
Genetic-epigenetic intersection in trophoblast differentiation: implications for extraembryonic tissue function.
    Epigenetics, 2010, Jan-01, Volume: 5, Issue:1

    Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation; Humans; Models, Biological; Models, Genetic; Placenta; Plants; Pregnancy; Stem Cells; Trophoblasts

2010
Epigenetic features of the mouse trophoblast.
    Reproductive biomedicine online, 2012, Volume: 25, Issue:1

    Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Histones; Mice; Models, Animal; Pregnancy; Pregnancy Complications; Trophoblasts

2012

Other Studies

23 other study(ies) available for 5-hydroxymethylcytosine and Pregnancy

ArticleYear
Gene by environment interaction mouse model reveals a functional role for 5-hydroxymethylcytosine in neurodevelopmental disorders.
    Genome research, 2022, Volume: 32, Issue:2

    Topics: 5-Methylcytosine; Animals; DNA Methylation; Epigenesis, Genetic; Female; Gene-Environment Interaction; Membrane Proteins; Mice; Nerve Tissue Proteins; Neurodevelopmental Disorders; Pregnancy

2022
Aberrant hydroxymethylation of
    Epigenetics, 2020, Volume: 15, Issue:8

    Topics: 5-Methylcytosine; Adult; Angiopoietin-Like Protein 4; Apoptosis; Cell Hypoxia; Cell Line; Cell Movement; DNA Methylation; Female; Fetal Growth Retardation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Placenta; Pregnancy; Pregnancy, Twin; Promoter Regions, Genetic; Trophoblasts

2020
Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing.
    Clinical epigenetics, 2020, 10-20, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Adult; Cell-Free Nucleic Acids; DNA Methylation; Down Syndrome; Epigenomics; Female; Fetal Diseases; Fetus; Genetic Testing; High-Throughput Nucleotide Sequencing; Humans; Male; Placenta; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity; Sequence Analysis, DNA; Trisomy

2020
Telomere Length in Chromosomally Normal and Abnormal Miscarriages and Ongoing Pregnancies and Its Association with 5-hydroxymethylcytosine Patterns.
    International journal of molecular sciences, 2021, Jun-21, Volume: 22, Issue:12

    Topics: 5-Methylcytosine; Abortion, Spontaneous; Case-Control Studies; Chorion; DNA Methylation; Female; Humans; Lymphocytes; Pregnancy; Pregnancy Trimester, First; Telomere; Telomere Homeostasis; Trophoblasts

2021
DNA Methylation program in normal and alcohol-induced thinning cortex.
    Alcohol (Fayetteville, N.Y.), 2017, Volume: 60

    Topics: 5-Methylcytosine; Alcohol Drinking; Animals; DNA Methylation; Epigenesis, Genetic; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Genotype; Gestational Age; Maternal Exposure; Mice, Inbred C57BL; Neocortex; Neurogenesis; Phenotype; Pregnancy

2017
Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.
    Epigenetics, 2018, Volume: 13, Issue:2

    Topics: 5-Methylcytosine; Brain; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Humans; Placenta; Pregnancy; snRNP Core Proteins; Ubiquitin-Protein Ligases

2018
Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: 5-Methylcytosine; Adiposity; Body Mass Index; DNA Methylation; Epigenesis, Genetic; Female; Genome, Human; Humans; Metabolome; Multigene Family; Obesity; Placenta; Pregnancy; Thinness

2017
Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol.
    Brain research bulletin, 2018, Volume: 139

    Topics: 5-Methylcytosine; Animals; Animals, Newborn; Cannabidiol; Creatine Kinase; Disease Models, Animal; DNA Methylation; DNA, Mitochondrial; Female; Gene Expression Regulation; Hippocampus; Iron Carbonyl Compounds; Male; Mitochondria; Mitochondrial Proteins; Muscle Proteins; NADH Dehydrogenase; Neurodegenerative Diseases; Pregnancy; Rats; Rats, Wistar

2018
Overexpression of Tet3 in donor cells enhances goat somatic cell nuclear transfer efficiency.
    The FEBS journal, 2018, Volume: 285, Issue:14

    Topics: 5-Methylcytosine; Animals; Blastocyst; Cellular Reprogramming; Cloning, Organism; Dioxygenases; DNA Demethylation; Embryonic Development; Female; Gene Expression Regulation, Developmental; Goats; Male; Nanog Homeobox Protein; Nuclear Transfer Techniques; Octamer Transcription Factor-3; Pregnancy

2018
Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss.
    Current medical science, 2018, Volume: 38, Issue:3

    Topics: 5-Methylcytosine; Abortion, Spontaneous; Adult; Dioxygenases; DNA; DNA-Binding Proteins; Female; Humans; Mixed Function Oxygenases; Pregnancy; Proto-Oncogene Proteins; RNA, Messenger; Trophoblasts

2018
TET2-Mediated Spatiotemporal Changes of 5-Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus.
    Anatomical record (Hoboken, N.J. : 2007), 2019, Volume: 302, Issue:6

    Topics: 5-Methylcytosine; Animals; Brain; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Fetus; Heart; Mice; Organogenesis; Pregnancy; Proto-Oncogene Proteins; Spatio-Temporal Analysis

2019
Trichloroethylene exposure in mid-pregnancy decreased fetal weight and increased placental markers of oxidative stress in rats.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 83

    Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; Dioxygenases; Female; Fetal Weight; Maternal-Fetal Exchange; Oxidative Stress; Placenta; Pregnancy; Rats, Wistar; Solvents; Trichloroethylene

2019
Inter-Cell and Inter-Chromosome Variability of 5-Hydroxymethylcytosine Patterns in Noncultured Human Embryonic and Extraembryonic Cells.
    Cytogenetic and genome research, 2018, Volume: 156, Issue:3

    Topics: 5-Methylcytosine; Cell Communication; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Humans; Pregnancy; Pregnancy Trimester, First

2018
Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development.
    Cryobiology, 2019, Volume: 87

    Topics: 5-Methylcytosine; Animals; Blastocyst; Cryopreservation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Fertilization in Vitro; Metaphase; Mice; Morula; Oocytes; Oogenesis; Pregnancy; Proto-Oncogene Proteins; Vitrification

2019
Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis.
    Life science alliance, 2019, Volume: 2, Issue:2

    Topics: 5-Methylcytosine; Animals; Cadherins; Cell Differentiation; Cell Lineage; CRISPR-Associated Protein 9; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Oncogene Proteins, Fusion; Pregnancy; Proto-Oncogene Proteins; Transcription Factors; Transcriptome

2019
Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation.
    Epigenetics, 2019, Volume: 14, Issue:7

    Topics: 5-Methylcytosine; Abortion, Legal; Adult; DNA Methylation; Epigenesis, Genetic; Female; Humans; Placenta; Placentation; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Trophoblasts

2019
Decreased global DNA hydroxymethylation in neural tube defects: Association with polycyclic aromatic hydrocarbons.
    Epigenetics, 2019, Volume: 14, Issue:10

    Topics: 5-Methylcytosine; Animals; Case-Control Studies; Disease Models, Animal; Embryo Culture Techniques; Female; Humans; Linear Models; Liver; Male; Maternal Exposure; Mice; Neural Tube Defects; Polycyclic Aromatic Hydrocarbons; Pregnancy; Superoxide Dismutase

2019
Altered expression of epigenetic regulators and imprinted genes in human placenta and fetal tissues from second trimester spontaneous pregnancy losses.
    Epigenetics, 2019, Volume: 14, Issue:12

    Topics: 5-Methylcytosine; Aborted Fetus; Abortion, Spontaneous; Adult; Cyclin-Dependent Kinase Inhibitor p57; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Placenta; Pregnancy; Pregnancy Trimester, Second; Proto-Oncogene Proteins; RNA, Long Noncoding

2019
Placental 5-methylcytosine and 5-hydroxymethylcytosine patterns associate with size at birth.
    Epigenetics, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Birth Weight; Cyclin-Dependent Kinase Inhibitor p57; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Placenta; Pregnancy

2015
Genome-Wide Mapping of 5mC and 5hmC Identified Differentially Modified Genomic Regions in Late-Onset Severe Preeclampsia: A Pilot Study.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: 5-Methylcytosine; Adult; Cytosine; DNA Methylation; Epigenesis, Genetic; ErbB Receptors; Female; Genome-Wide Association Study; Genome, Human; Humans; Pilot Projects; Pre-Eclampsia; Pregnancy; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Signal Transduction

2015
5-Hydroxymethylcytosine-mediated alteration of transposon activity associated with the exposure to adverse in utero environments in human.
    Human molecular genetics, 2016, 06-01, Volume: 25, Issue:11

    Topics: 5-Methylcytosine; Adult; Ascorbic Acid; Diabetes, Gestational; Dioxygenases; DNA Methylation; DNA Transposable Elements; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Humans; Pre-Eclampsia; Pregnancy; Proto-Oncogene Proteins

2016
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
    Nutrients, 2016, Aug-06, Volume: 8, Issue:8

    Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report

2016
Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.
    Neurobiology of aging, 2013, Volume: 34, Issue:1

    Topics: 5-Methylcytosine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavioral Symptoms; Benzofurans; Cognition Disorders; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Presenilin-1; Quinolines; Space Perception; Stress, Psychological

2013