Page last updated: 2024-08-25

5-hydroxymethylcytosine and Neoplasms

5-hydroxymethylcytosine has been researched along with Neoplasms in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	44 (86.27)	24.3611
2020's	7 (13.73)	2.80

Authors

Authors	Studies
Chen, L; Hou, P; Li, K; Su, J; Sun, J; Wang, Y; Yan, C; Zhao, J; Zhou, M	1
Lu, MJ; Lu, Y	1
Hu, J; Li, DL; Qiu, JG; Wang, ZY; Yuan, H; Zhang, CY	1
Fader, KA; Gosink, MM; Halsey, C; Lanz, TA; Radi, ZA; Vaidya, VS; Xia, S	1
Skvortsova, K; Stirzaker, C; Taberlay, P	1
Gao, H; Xu, T	1
Andreou, AZ; Kouidou, S; Malousi, A	1
Fernández, AF; Fraga, MF; López, V	1
Chen, Y; Chua, MS; Diao, J; Dong, B; Hu, J; Jeffrey, SS; Li, W; Liu, B; Ma, L; Quake, SR; So, S; Song, CX; Tian, Z; Wei, Y; Wheeler, A; Xie, D; Xiong, J; Yin, S; Zhang, W; Zhang, Y; Zhou, Z	1
Adhikari, S; Bissonnette, MB; Chen, G; Cui, M; Dai, M; Dong, Y; Hao, H; He, C; Hong, J; Hua, L; Jia, G; Li, W; Liao, Q; Liu, J; Liu, Z; Lu, X; Luo, F; Luo, Z; Meckel, K; Nie, J; Qian, X; Shi, J; Song, Y; Wang, P; Wang, Y; Wei, L; Xu, D; You, L; Yu, S; Yuan, F; Zhang, J; Zhang, T; Zhang, W; Zhang, X; Zhao, Y; Zheng, W	1
Aguilar, S; Argilés, G; Arqués, O; Arroyo, AG; Caratù, G; Casanovas, O; Chicote, I; Cuesta-Borrás, E; Dienstmann, R; Eguizabal, C; Gonzalo, P; Landolfi, S; Martínez-Quintanilla, J; Nuciforo, P; Palmer, HG; Prat, A; Puig, I; Ramírez, L; Recio, JA; Seoane, J; Serra, V; Soto, A; Tabernero, J; Tenbaum, SP; Terracciano, L; Villanueva, A; Vivancos, A	1
Adler, GK; Argueta, C; Chen, H; Chen, J; Dong, Z; Duquette, D; Fan, J; Fang, R; Fetahu, IS; Garg, R; Geng, S; Hu, D; Lan, F; Li, Y; Lian, CG; Liu, H; Lv, R; Lynch, L; Mao, F; Murphy, GF; Rabidou, K; Shi, G; Shi, Y; Shi, YG; Tan, L; Wang, M; Wu, D; Wu, F; Xu, S; Xu, Y; Yan, G; Yang, P; Ye, Y; Yin, C; Zhang, L; Zhang, S	1
Pfeifer, GP; Szabó, PE	1
Krais, AM; Meister, M; Park, YJ; Plass, C; Reifenberger, G; Schmeiser, HH	1
Bogdanovic, O; Clark, SJ; Colino-Sanguino, Y; Du, Q; Goodnow, CC; Gould, CM; Horvath, L; Kench, JG; Khoury, A; Lim, SM; Luu, PL; Masle-Farquhar, E; Miosge, LA; Nair, SS; Peters, TJ; Pidsley, R; Polo, JM; Qu, W; Reed, JH; Rubin, MA; Skvortsova, K; Smith, GC; Song, JZ; Stirzaker, C; Zotenko, E	1
Chiu, BC; Stroup, EK; Zeng, C; Zhang, W; Zhang, Z	1
Benner, A; Slynko, A	1
Avraham, S; Caspi, M; Ebenstein, Y; Friedmann-Morvinski, D; Gilat, N; Kariv, R; Lahat, G; Loewenstein, S; Magod, P; Margalit, S; Michaeli, Y; Rosin-Arbesfeld, R; Shahal, T; Zirkin, S	1
De Marzo, AM; Ghosh, S; Haffner, MC; Lotan, TL; Nelson, WG; Pellakuru, LG; Yegnasubramanian, S	1
Błasiak, J; Głowacki, S	1
Cadet, J; Wagner, JR	1
Kohli, RM; Zhang, Y	1
Li, L; Ye, C	1
Harrison, DJ; Laird, A; Meehan, RR; Thomson, JP	1
Ling, ZQ; Wu, YC	1
Hahn, MA; Jin, SG; Pfeifer, GP; Xiong, W	1
Delatte, B; Deplus, R; Fuks, F	1
Arab, K; Dienemann, H; Dyckhoff, G; Grummt, I; Herold-Mende, C; Lindroth, AM; Lukanova, A; Lundin, E; Meister, M; Niehrs, C; Oakes, C; Park, YJ; Plass, C; Risch, A; Schäfer, A; Weichenhan, D	1
Huang, Y; Rao, A	1
Chen, T; Chen, Y; Frank, MY; Guo, W; Lian, CG; Liu, C; Liu, R; Murphy, GF; Xu, S; Yan, J	1
Ficz, G; Gribben, JG	1
Chatterjee, A; Morison, IM; Rodger, EJ	1
Cho, IH; Chowdhury, B; Hahn, N; Irudayaraj, J	1
Jansen, JH; Kroeze, LI; van der Reijden, BA	1
Sehgal, M; Shukla, A; Singh, TR	1
Godley, LA; Vasanthakumar, A	1
Barry, WT; Beroukhim, R; Birkbak, NJ; Clark, AP; Culhane, AC; Eklund, AC; Hill, DE; Landini, S; Lim, E; Neupane, M; Schumacher, SE; Silver, DP; Szallasi, Z; Vidal, M	1
Bi, C; Cai, B; Liang, J; Yang, F; Zhao, L	1
Jin, WL; Li, WB; Lian, H	1
Feinberg, A; Hansen, KD; Li, X; Liu, Y; Salz, T	1
Bhoopatiraju, S; Forster, CL; Freeman, MJ; Hallstrom, TC; Linden, MA; Lu, H; Schmitz, NP; Verneris, MR; Wang, H; Wang, X	1
Chen, Z; Guo, L; He, J; Li, Y; Luo, M; Shi, X	1
Meehan, RR; Thomson, JP	1
Baylin, SB; Cai, Y; Easwaran, H; Li, Y; Luo, J; Wang, Z; Xia, L; Xie, W; Yen, RC; Zhang, YW	1
Carell, T; Globisch, D; Münzel, M	1
Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y	1
Aburatani, H; Asaoka, Y; Ijichi, H; Koike, K; Kudo, Y; Nagae, G; Tateishi, K; Yamamoto, K; Yamamoto, S; Yoshida, H	1
Bai, F; Guan, KL; Ling, ZQ; Liu, J; Liu, Y; Ma, SH; Xiong, Y; Xu, ZD; Yang, H; Ye, D; Zhang, JY; Zhu, HG	1
Shi, YG; Tan, L	1
Guz, J; Jurgowiak, M; Oliński, R	1
Kinney, SR; Pradhan, S	1

Reviews

26 review(s) available for 5-hydroxymethylcytosine and Neoplasms

Article	Year
The DNA methylation landscape in cancer. Essays in biochemistry, 2019, 12-20, Volume: 63, Issue:6 Topics: 5-Methylcytosine; Animals; DNA; DNA Methylation; Epigenomics; Humans; Neoplasms	2019
Hydroxymethylation and tumors: can 5-hydroxymethylation be used as a marker for tumor diagnosis and treatment? Human genomics, 2020, 05-06, Volume: 14, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms	2020
The role of 5-hydroxymethylcytosine in development, aging and age-related diseases. Ageing research reviews, 2017, Volume: 37 Topics: 5-Methylcytosine; Aging; Animals; Cell Differentiation; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Oxidation-Reduction	2017
Towards precision medicine: advances in 5-hydroxymethylcytosine cancer biomarker discovery in liquid biopsy. Cancer communications (London, England), 2019, 03-29, Volume: 39, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell-Free Nucleic Acids; Epigenomics; Humans; Liquid Biopsy; Neoplasms; Precision Medicine	2019
[Role of 5-hydroxymethylcytosine and TET proteins in epigenetic regulation of gene expression]. Postepy biochemii, 2013, Volume: 59, Issue:1 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Hematopoiesis; Humans; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2013
TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine. Mutation research. Genetic toxicology and environmental mutagenesis, 2014, Volume: 764-765 Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA Repair; Humans; Models, Biological; Mutagenesis; Neoplasms; Oxidation-Reduction	2014
TET enzymes, TDG and the dynamics of DNA demethylation. Nature, 2013, Oct-24, Volume: 502, Issue:7472 Topics: 5-Methylcytosine; Animals; Blastocyst; Cellular Reprogramming; Cytosine; DNA Methylation; DNA Repair; DNA Replication; Humans; Neoplasms; Oxidation-Reduction; Thymine DNA Glycosylase	2013
5-hydroxymethylcytosine: a new insight into epigenetics in cancer. Cancer biology & therapy, 2014, Volume: 15, Issue:1 Topics: 5-Methylcytosine; Animals; Brain Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Leukemia; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2014
5-hydroxymethylcytosine profiling as an indicator of cellular state. Epigenomics, 2013, Volume: 5, Issue:6 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Models, Genetic; Neoplasms; Organ Specificity; Signal Transduction	2013
The role of TET family proteins and 5-hydroxymethylcytosine in human tumors. Histology and histopathology, 2014, Volume: 29, Issue:8 Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Neoplasms	2014
The role of 5-hydroxymethylcytosine in human cancer. Cell and tissue research, 2014, Volume: 356, Issue:3 Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Neoplasms; Oxidation-Reduction	2014
Playing TETris with DNA modifications. The EMBO journal, 2014, Jun-02, Volume: 33, Issue:11 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Signal Transduction	2014
Connections between TET proteins and aberrant DNA modification in cancer. Trends in genetics : TIG, 2014, Volume: 30, Issue:10 Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries	2014
Loss of 5-hydroxymethylcytosine in cancer: cause or consequence? Genomics, 2014, Volume: 104, Issue:5 Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Humans; Mixed Function Oxygenases; Neoplasms; Oxidation-Reduction; Proto-Oncogene Proteins	2014
5-hydroxymethylcytosine: a potential therapeutic target in cancer. Epigenomics, 2014, Volume: 6, Issue:5 Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms	2014
5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer. Biochimica et biophysica acta, 2015, Volume: 1855, Issue:2 Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasms; Proto-Oncogene Proteins	2015
Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives. Gene, 2015, Jun-15, Volume: 564, Issue:2 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Repair; Humans; Mental Disorders; Neoplasms; Neurodegenerative Diseases	2015
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy. Cancer genetics, 2015, Volume: 208, Issue:5 Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Humans; Isocitrate Dehydrogenase; Neoplasms; Proto-Oncogene Proteins	2015
Physiological and pathological implications of 5-hydroxymethylcytosine in diseases. Oncotarget, 2016, 07-26, Volume: 7, Issue:30 Topics: 5-Methylcytosine; CpG Islands; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Demethylation; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Mixed Function Oxygenases; Neoplasms; Nervous System Diseases; Promoter Regions, Genetic; Proto-Oncogene Proteins	2016
The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development. Oncotarget, 2016, Sep-27, Volume: 7, Issue:39 Topics: 5-Methylcytosine; Animals; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Nerve Tissue Proteins; Neurogenesis; Neurons; Protein Conformation; Signal Transduction; Structure-Activity Relationship	2016
Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis. Oncotarget, 2017, Jan-03, Volume: 8, Issue:1 Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Lymphatic Metastasis; Neoplasms; Prognosis	2017
The application of genome-wide 5-hydroxymethylcytosine studies in cancer research. Epigenomics, 2017, Volume: 9, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Sequence Analysis, DNA	2017
5-Hydroxymethylcytosine, the sixth base of the genome. Angewandte Chemie (International ed. in English), 2011, Jul-11, Volume: 50, Issue:29 Topics: 5-Methylcytosine; Animals; Bacteriophages; Cell Differentiation; Central Nervous System; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Female; Genome; Humans; Male; Mass Spectrometry; Neoplasms; Pluripotent Stem Cells	2011
Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development (Cambridge, England), 2012, Volume: 139, Issue:11 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Epigenesis, Genetic; Humans; Mice; Mice, Knockout; Molecular Structure; Multigene Family; Neoplasms; Oxidation-Reduction; Protein Structure, Tertiary; Proto-Oncogene Proteins	2012
[Oxidation and deamination of nucleobases as an epigenetic tool]. Postepy higieny i medycyny doswiadczalnej (Online), 2012, May-24, Volume: 66 Topics: 5-Methylcytosine; Animals; Base Composition; Chromatin Assembly and Disassembly; Cytosine; Deamination; DNA; DNA Methylation; DNA-Binding Proteins; Epigenomics; Gene Expression Regulation; Guanine; Mutation; Neoplasms; Oxidation-Reduction; Sequence Analysis, DNA; Transcription, Genetic	2012
Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer. Advances in experimental medicine and biology, 2013, Volume: 754 Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Humans; Neoplasms; Proto-Oncogene Proteins	2013

Other Studies

25 other study(ies) available for 5-hydroxymethylcytosine and Neoplasms

Article	Year
Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers. Clinical epigenetics, 2021, 10-24, Volume: 13, Issue:1 Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; Disease Progression; Early Detection of Cancer; Humans; Neoplasms; RNA, Long Noncoding	2021
5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection. BMC research notes, 2022, Apr-21, Volume: 15, Issue:1 Topics: 5-Methylcytosine; DNA; DNA Methylation; Humans; Mutation; Neoplasms	2022
Hydroxymethylation-Specific Ligation-Mediated Single Quantum Dot-Based Nanosensors for Sensitive Detection of 5-Hydroxymethylcytosine in Cancer Cells. Analytical chemistry, 2022, 07-12, Volume: 94, Issue:27 Topics: 5-Methylcytosine; Animals; Biotin; DNA; DNA Methylation; Mammals; Neoplasms; Quantum Dots	2022
Thymic lymphoma detection in RORγ knockout mice using 5-hydroxymethylcytosine profiling of circulating cell-free DNA. Toxicology and applied pharmacology, 2023, Aug-15, Volume: 473 Topics: Animals; Cell-Free Nucleic Acids; Humans; Infant; Mice; Mice, Knockout; Neoplasms; Nuclear Receptor Subfamily 1, Group F, Member 3	2023
In silico structural analysis of sequences containing 5-hydroxymethylcytosine reveals its potential as binding regulator for development, ageing and cancer-related transcription factors. Epigenetics, 2021, Volume: 16, Issue:5 Topics: 5-Methylcytosine; Aging; DNA Methylation; G-Quadruplexes; Humans; Neoplasms; Transcription Factors	2021
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages. Cell research, 2017, Volume: 27, Issue:10 Topics: 5-Methylcytosine; Adult; Aged; Animals; Cell-Free Nucleic Acids; Circulating Tumor DNA; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms	2017
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers. Cell research, 2017, Volume: 27, Issue:10 Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Biomarkers, Tumor; Cell-Free Nucleic Acids; Circulating Tumor DNA; DNA Methylation; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Humans; Liquid Biopsy; Male; Middle Aged; Neoplasms; Young Adult	2017
TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence. The Journal of clinical investigation, 2018, 08-31, Volume: 128, Issue:9 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Cycle; Cell Line, Tumor; Cell Survival; Dioxygenases; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Knockdown Techniques; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Proto-Oncogene Proteins; Recurrence; Xenograft Model Antitumor Assays	2018
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature, 2018, Volume: 559, Issue:7715 Topics: 5-Methylcytosine; Adenylate Kinase; Animals; Diabetes Mellitus; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Enzyme Stability; Epigenesis, Genetic; Glucose; Glycated Hemoglobin; Humans; Hyperglycemia; Metformin; Mice; Mice, Nude; Neoplasms; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Substrate Specificity; Xenograft Model Antitumor Assays	2018
Gene body profiles of 5-hydroxymethylcytosine: potential origin, function and use as a cancer biomarker. Epigenomics, 2018, Volume: 10, Issue:8 Topics: 5-Methylcytosine; Biomarkers, Tumor; Genome; Humans; Neoplasms	2018
Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues. Electrophoresis, 2019, Volume: 40, Issue:9 Topics: 5-Methylcytosine; Animals; Cell Dedifferentiation; DNA Methylation; Electrophoresis, Capillary; Fluorescence; Glioma; Humans; Lung Neoplasms; Mice; Neoplasms	2019
DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns. Cancer cell, 2019, 02-11, Volume: 35, Issue:2 Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; CpG Islands; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic	2019
Statistical methods for classification of 5hmC levels based on the Illumina Inifinium HumanMethylation450 (450k) array data, under the paired bisulfite (BS) and oxidative bisulfite (oxBS) treatment. PloS one, 2019, Volume: 14, Issue:6 Topics: 5-Methylcytosine; Case-Control Studies; DNA Methylation; Humans; Neoplasms; Oxidation-Reduction; Sulfites	2019
5-Hydroxymethylcytosine as a clinical biomarker: Fluorescence-based assay for high-throughput epigenetic quantification in human tissues. International journal of cancer, 2020, 01-01, Volume: 146, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cost-Benefit Analysis; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Mice; Neoplasms; Proof of Concept Study	2020
Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease. Cell cycle (Georgetown, Tex.), 2013, Jun-15, Volume: 12, Issue:12 Topics: 5-Methylcytosine; Cell Differentiation; Cell Line, Tumor; Cytosine; DNA Methylation; Epigenomics; Female; Histones; Humans; In Vitro Techniques; Male; Neoplasms; Polycomb-Group Proteins	2013
Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A. Molecular cell, 2014, Aug-21, Volume: 55, Issue:4 Topics: 5-Methylcytosine; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Cytosine; DNA Methylation; DNA Repair; Gene Expression Regulation, Neoplastic; Genome, Human; HEK293 Cells; Humans; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; Thymine DNA Glycosylase	2014
Decrease of 5-hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid. Molecular carcinogenesis, 2015, Volume: 54, Issue:11 Topics: 5-Methylcytosine; Animals; Aristolochic Acids; Carcinogenesis; Carcinogens; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Liver; Mutation; Neoplasms; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Transgenic	2015
Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay. Analytica chimica acta, 2014, Dec-10, Volume: 852 Topics: 5-Methylcytosine; Cytosine; DNA; Epigenesis, Genetic; Humans; Immunoenzyme Techniques; Limit of Detection; Neoplasms	2014
MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. Cancer discovery, 2016, Volume: 6, Issue:1 Topics: 5-Methylcytosine; Alternative Splicing; Animals; Cell Line, Tumor; Cytosine; Epigenesis, Genetic; Gene Amplification; Humans; Methyl-CpG-Binding Protein 2; Mice; Neoplasm Transplantation; Neoplasms; Protein Isoforms; ras Proteins; Signal Transduction	2016
Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver. Genome research, 2016, Volume: 26, Issue:12 Topics: 5-Methylcytosine; CpG Islands; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Lung; Neoplasms; Organ Specificity; Promoter Regions, Genetic; Whole Genome Sequencing	2016
Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity. Oncotarget, 2016, Nov-15, Volume: 7, Issue:46 Topics: 5-Methylcytosine; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lymphocytes; Lymphoid Progenitor Cells; Neoplasm Grading; Neoplasms; Promoter Regions, Genetic; Protein Transport; Ubiquitin-Protein Ligases	2016
Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress. Molecular cell, 2017, Jan-19, Volume: 65, Issue:2 Topics: 5-Methylcytosine; Acetylation; Chromatin; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; E1A-Associated p300 Protein; HCT116 Cells; Histone Deacetylase 1; Histone Deacetylase 2; Humans; Neoplasms; Oxidative Stress; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Proto-Oncogene Proteins; RNA Interference; Time Factors; Transfection; Ubiquitination	2017
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer research, 2011, Dec-15, Volume: 71, Issue:24 Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Lung Neoplasms; Male; Mice; Mixed Function Oxygenases; Molecular Structure; Mutation; Neoplasms; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction	2011
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer science, 2012, Volume: 103, Issue:4 Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA-Binding Proteins; Gene Knockdown Techniques; Humans; Mixed Function Oxygenases; Mutation; Neoplasms; Proto-Oncogene Proteins; Stomach Neoplasms	2012
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene, 2013, Jan-31, Volume: 32, Issue:5 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Humans; Hydroxylation; Mice; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2013