Page last updated: 2024-08-25

5-hydroxymethylcytosine and Disease Exacerbation

5-hydroxymethylcytosine has been researched along with Disease Exacerbation in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's16 (88.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Chen, L; Hou, P; Li, K; Su, J; Sun, J; Wang, Y; Yan, C; Zhao, J; Zhou, M1
Bassis, CM; Evans, MC; Feldman, EL; Figueroa-Romero, C; Guo, K; Hur, J; McDermott, AJ; Mikhail, KA; Murdock, BJ; O'Brien, PD; Paez-Colasante, X; Pawlowski, KD; Savelieff, MG; Taubman, GF1
Ali, M; Coleman, PD; Del Sol, A; Delvaux, E; Eijssen, LMT; Hoffmann, P; Hurlemann, R; Iatrou, A; Jessen, F; Kawalia, A; Kenis, G; Kleineidam, L; Lardenoije, R; Leber, M; Luck, T; Lunnon, K; Maier, W; Mastroeni, D; Mill, J; Pishva, E; Ramirez, A; Riedel-Heller, S; Roubroeks, JAY; Rutten, BPF; Smith, AR; Smith, RG; van den Hove, DLA; Wagner, H; Wagner, M1
Allen, EG; Barwick, BG; Castellino, RC; Chen, J; Chen, L; Conneely, KN; Jin, P; Johnson, ND; Kang, Y; Kenney, AM; Kim, H; Li, J; Li, Y; Liao, X; Lin, L; McSwain, L; Robinson, MH; Shu, Q; Van Meir, EG; Vertino, PM; Yuan, X; Zhang, Z; Zhao, J; Zhu, D1
Dinulescu, DM; Getchell, CR; Gupta, M; Hasselblatt, KT; Hirsch, MS; Kaplan, SJ; Ko, JY; Lee, JJ; Li, W; Lian, CG; Liu, JF; MacDonald, LA; Malik, A; Matulonis, UA; McCarthy, ET; Medina, JE; Murphy, GF; Ohman, AW; Sasamoto, N; Shafrir, A; Terry, KL; Tucker, DW; Xu, S; Zhang, H1
Chen, H; Duan, X; Gan, L; Jaypaul, H; Liu, N; Liu, X; Makamure, JT; Ming, Z; Wang, X; Zhang, S; Zhu, K1
Li, X; Lian, CG; Liu, F; Liu, X; Qiu, L; Tu, P; Wang, Y; Xiao, C; Yi, S1
Bizet, M; Bonvin, E; Calonne, E; Fuks, F; Larue, L; Luciani, F; Marine, JC; Nittner, D; Petit, V; Putmans, P; Radaelli, E; Santagostino, SF; Singh, NK1
Gambichler, T; Sand, M; Skrygan, M1
Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z1
Meehan, RR; Moggs, JG; Thomson, JP; Wolf, CR1
Coppieters, N; Curtis, MA; Dieriks, BV; Dragunow, M; Faull, RL; Lill, C1
Fujimura, T; Hayashizaki, Y; Homma, Y; Inoue, S; Misawa, A; Suzuki, T; Takagi, K; Takahashi, S; Takayama, K; Urano, T1
Fraitag, S; Hohl, D; Pavlova, O1
Chen, L; Gong, F; Guo, Y; Jin, J; Li, R; Ma, RZ; Niu, Y; Shi, X; Zhang, L; Zhang, X1
Abner, EL; Ellison, EM; Lovell, MA1
Ahn, JS; Ahn, SY; Choi, SH; Jang, JH; Jung, CW; Jung, SH; Kim, DD; Kim, HJ; Kim, SH; Kim, YK; Lee, JJ; Lee, SS; Michael, S; Minden, MD; Moon, JH; Park, HJ; Sohn, SK; Won, JH; Yang, DH1
Albasanz, JL; Barrachina, M; Blanch, M; Ferrer, I; Martín, M; Pereira-Veiga, T; Pérez-Navarro, E; Tyebji, S; Villar-Menéndez, I1

Reviews

1 review(s) available for 5-hydroxymethylcytosine and Disease Exacerbation

ArticleYear
Epigenetic profiles as defined signatures of xenobiotic exposure.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2014, Volume: 764-765

    Topics: 5-Methylcytosine; Animals; Carcinogens; Chemical Safety; Chromatin; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genetic Markers; Genome; Humans; Transcriptome; Xenobiotics

2014

Other Studies

17 other study(ies) available for 5-hydroxymethylcytosine and Disease Exacerbation

ArticleYear
Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers.
    Clinical epigenetics, 2021, 10-24, Volume: 13, Issue:1

    Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; Disease Progression; Early Detection of Cancer; Humans; Neoplasms; RNA, Long Noncoding

2021
Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice.
    Disease models & mechanisms, 2019, 11-15, Volume: 13, Issue:2

    Topics: 5-Methylcytosine; Amyotrophic Lateral Sclerosis; Animals; Bacteria; Brain; Disease Progression; Epigenome; Feces; Female; Gastrointestinal Microbiome; Immune System; Inflammation; Leukocytes; Male; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Phenotype; Phylogeny; Superoxide Dismutase-1; Time Factors

2019
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.
    Clinical epigenetics, 2019, 11-27, Volume: 11, Issue:1

    Topics: 5-Methylcytosine; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Oxytocin; Receptors, Nicotinic; Temporal Lobe

2019
Ten-eleven translocation protein 1 modulates medulloblastoma progression.
    Genome biology, 2021, 04-29, Volume: 22, Issue:1

    Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Computational Biology; CpG Islands; Databases, Nucleic Acid; Disease Models, Animal; Disease Progression; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; Mice; Mice, Transgenic; Mixed Function Oxygenases; Nucleotide Motifs; Prognosis; Proto-Oncogene Proteins

2021
Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 03-15, Volume: 24, Issue:6

    Topics: 5-Methylcytosine; Animals; Cell Survival; Cellular Reprogramming; Combined Modality Therapy; Cystadenocarcinoma, Serous; Dioxygenases; Disease Models, Animal; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Grading; Ovarian Neoplasms; Prognosis; Proto-Oncogene Proteins; Recurrence; Survival Analysis; Xenograft Model Antitumor Assays

2018
Ten-eleven Translocation-2 Regulates DNA Hydroxymethylation Status and Psoriasiform Dermatitis Progression in Mice.
    Acta dermato-venereologica, 2018, Jun-08, Volume: 98, Issue:6

    Topics: 5-Methylcytosine; Aminoquinolines; Animals; Case-Control Studies; Cell Differentiation; Cell Proliferation; Chemokine CXCL1; Dioxygenases; Disease Models, Animal; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Humans; Imiquimod; Interferon-gamma; Interleukin-17; Mice, Inbred BALB C; Proto-Oncogene Proteins; Psoriasis; Skin; Time Factors

2018
Loss of 5-Hydroxymethylcytosine Is an Epigenetic Biomarker in Cutaneous T-Cell Lymphoma.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:11

    Topics: 5-Methylcytosine; Apoptosis; Biomarkers, Tumor; Carcinogenesis; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Female; Humans; Keratinocytes; Lymphoma, T-Cell, Cutaneous; Male; Mycosis Fungoides; Neoplasm Staging; Prognosis; Skin Neoplasms; Survival Analysis

2018
TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
    Cancer research, 2019, 02-01, Volume: 79, Issue:3

    Topics: 5-Methylcytosine; Animals; Dioxygenases; Disease Progression; DNA-Binding Proteins; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Monomeric GTP-Binding Proteins; Proto-Oncogene Proteins; Rats; Skin Neoplasms

2019
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
    Melanoma research, 2013, Volume: 23, Issue:3

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Proteins; Epigenomics; Humans; Melanoma; Paraffin Embedding; Proto-Oncogene Proteins; Skin Neoplasms; Translocation, Genetic

2013
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine; Diethylnitrosamine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins; Rats, Wistar

2013
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.
    Neurobiology of aging, 2014, Volume: 35, Issue:6

    Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Genetic Markers; Humans; Male; Microglia; Middle Aged; Neurons; Parahippocampal Gyrus

2014
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
    Nature communications, 2015, Sep-25, Volume: 6

    Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cytosine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hepatocyte Nuclear Factor 3-alpha; Humans; Hydroxylation; Immunohistochemistry; Male; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Neoplasm Transplantation; Prostatic Neoplasms; Proto-Oncogene Proteins; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, RNA; TOR Serine-Threonine Kinases

2015
5-Hydroxymethylcytosine Expression in Proliferative Nodules Arising within Congenital Nevi Allows Differentiation from Malignant Melanoma.
    The Journal of investigative dermatology, 2016, Volume: 136, Issue:12

    Topics: 5-Methylcytosine; Adult; Analysis of Variance; Biopsy, Needle; Cohort Studies; Diagnosis, Differential; Disease Progression; Dysplastic Nevus Syndrome; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Melanoma; Melanoma, Cutaneous Malignant; Nevus, Pigmented; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Retrospective Studies; Skin Neoplasms

2016
Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma.
    Oncotarget, 2017, Jan-03, Volume: 8, Issue:1

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; Dioxygenases; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Demethylation; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Small Interfering; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays

2017
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease.
    Journal of neurochemistry, 2017, Volume: 140, Issue:3

    Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Epigenesis, Genetic; Female; Gas Chromatography-Mass Spectrometry; Humans; Male

2017
5-Hydroxymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Dioxygenases; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Phenotype; Predictive Value of Tests; Proportional Hazards Models; Proto-Oncogene Proteins; Recurrence; Time Factors; Treatment Outcome; Young Adult

2017
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease.
    Neuromolecular medicine, 2013, Volume: 15, Issue:2

    Topics: 5-Methylcytosine; 5' Untranslated Regions; Adult; Aged; Aged, 80 and over; Animals; Corpus Striatum; Cytosine; Disease Models, Animal; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins; Putamen; Receptor, Adenosine A2A

2013