5-hydroxymethylcytosine has been researched along with Alzheimer Disease in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (70.83) | 24.3611 |
| 2020's | 7 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; He, X; Li, D; Pei, S; Shen, Q; Wang, Q; Xu, S; Yu, H; Zhang, Y | 1 |
| Arvanitakis, Z; Beadell, AV; Bennett, DA; Capuano, AW; He, C; Zhang, W; Zhang, Z | 1 |
| Ali, M; Coleman, PD; Del Sol, A; Delvaux, E; Eijssen, LMT; Hoffmann, P; Hurlemann, R; Iatrou, A; Jessen, F; Kawalia, A; Kenis, G; Kleineidam, L; Lardenoije, R; Leber, M; Luck, T; Lunnon, K; Maier, W; Mastroeni, D; Mill, J; Pishva, E; Ramirez, A; Riedel-Heller, S; Roubroeks, JAY; Rutten, BPF; Smith, AR; Smith, RG; van den Hove, DLA; Wagner, H; Wagner, M | 1 |
| Allen, EG; Chen, C; Chen, L; Guo, J; Jin, P; Li, Y; Li, Z; Liu, Z; Ma, C; Qin, L; Shen, L; Tang, B; Wu, H; Xu, Q; Yang, N; Zhu, X | 1 |
| Li, L; Li, W; Liu, Z; Miao, M; Qiu, Y; Wang, Q; Zhu, Y | 1 |
| Cao, D; Jiang, D; Li, J; Yu, H; Zhou, D | 1 |
| Chow, HM; Herrup, K; Li, J; Li, L; Ma, Z; Xu, K; Zhang, Y; Zhang, Z | 1 |
| Bruggeman, EC; Chen, J; Chen, L; Hales, CM; Kuehner, JN; Li, Y; Li, Z; McEachin, ZT; Wang, F; Wen, Z; Xu, C; Yang, J; Yao, B | 1 |
| Lunnon, K; Smith, RG | 1 |
| Bradley-Whitman, MA; Ellison, EM; Lovell, MA | 1 |
| Cai, C; Huang, Q; Li, J; Liu, Z; Mo, M; Xu, S; Yang, Q; Ye, X; Zhang, J; Zhang, L; Zhong, Y | 1 |
| Coppieters, N; Curtis, MA; Dieriks, BV; Dragunow, M; Faull, RL; Lill, C | 1 |
| Chouliaras, L; Condliffe, D; Cooper, J; Fernandes, C; Lovestone, S; Lunnon, K; Mill, J; Patel, Y; Proitsi, P; Schalkwyk, L; Troakes, C; Wong, A | 1 |
| Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C | 1 |
| Balazs, R; Gami, P; Lashley, T; Li, A; Revesz, T; Valizadeh, N | 1 |
| Celarain, N; Echavarri, C; Larumbe, R; Mendioroz, M; Pulido, L; Roldán, M; Sánchez-Ruiz de Gordoa, J; Zelaya, MV | 1 |
| Bao, H; Bernstein, AI; Dai, Q; Duan, R; Gearing, M; He, C; Jin, P; Lah, JJ; Levey, AI; Lin, L; Lin, Y; Mullé, JG; Nelson, PT; Street, RC; Yu, L | 1 |
| Huang, L; Jin, P; Li, L; Li, X; Lin, L; Shen, H; Shu, L; Sun, W; Xie, P; Xu, Q; Xu, Z | 1 |
| Phipps, AJ; Taberlay, PC; Vickers, JC; Woodhouse, A | 1 |
| Abner, EL; Ellison, EM; Lovell, MA | 1 |
| Chouliaras, L; Rutten, BP; van den Hove, DL | 1 |
| Irier, HA; Jin, P | 1 |
| Chen, H; Dzitoyeva, S; Manev, H | 1 |
| Chouliaras, L; Delbroek, L; Prickaerts, J; Rostamian, S; Rutten, BP; Sierksma, AS; Steinbusch, HW; van den Hove, DL | 1 |
2 review(s) available for 5-hydroxymethylcytosine and Alzheimer Disease
| Article | Year |
|---|---|
DNA Modifications and Alzheimer's Disease.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Causality; Disease Models, Animal; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Forecasting; Gene Expression Regulation; Genome-Wide Association Study; Humans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Tissue Array Analysis | 2017 |
Dynamics of DNA methylation in aging and Alzheimer's disease.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; DNA; DNA Methylation; Humans; Neurodegenerative Diseases | 2012 |
22 other study(ies) available for 5-hydroxymethylcytosine and Alzheimer Disease
| Article | Year |
|---|---|
5-Hydroxymethylcytosine Signatures in Circulating Cell-Free DNA as Diagnostic Biomarkers for Late-Onset Alzheimer's Disease.
Topics: 5-Methylcytosine; Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Cell-Free Nucleic Acids; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged | 2022 |
Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
Topics: 5-Methylcytosine; Alzheimer Disease; Cell-Free Nucleic Acids; Diabetes Mellitus; DNA Methylation; Humans | 2023 |
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.
Topics: 5-Methylcytosine; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Oxytocin; Receptors, Nicotinic; Temporal Lobe | 2019 |
Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Basic Helix-Loop-Helix Transcription Factors; Brain; Computational Biology; DNA Methylation; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; RNA-Seq | 2020 |
Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Topics: 5-Methylcytosine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Differentiation; Cognitive Dysfunction; Dioxygenases; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation; Hippocampus; Histone Deacetylase 1; Humans; Learning; Mice; Mice, Transgenic; Neural Stem Cells; Proto-Oncogene Proteins; RNA-Seq | 2020 |
A Comparative Study on 5hmC Targeting Regulation of Neurons in AD Mice by Several Natural Compounds.
Topics: 5-Methylcytosine; Alzheimer Disease; Animals; Cell Line, Tumor; Deoxyadenosines; Disease Models, Animal; Humans; Mice; Mice, Mutant Strains; Neurons; Resveratrol | 2020 |
Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Alzheimer Disease; Animals; Astrocytes; Brain; Cell Line; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genome; HEK293 Cells; Humans; Mice; Neurodegenerative Diseases; Neurons | 2020 |
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease.
Topics: 5-Methylcytosine; Alzheimer Disease; Animals; Humans; Mice; Neurogenesis; Organoids; Prosencephalon | 2021 |
Single-Base Resolution Mapping of 5-Hydroxymethylcytosine Modifications in Hippocampus of Alzheimer's Disease Subjects.
Topics: 5-Methylcytosine; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; DNA Methylation; Epigenesis, Genetic; Female; Hippocampus; Humans; Male | 2017 |
Quantification of DNA methylation and hydroxymethylation in Alzheimer's disease mouse model using LC-MS/MS.
Topics: 5-Methylcytosine; Alzheimer Disease; Animals; Biomarkers; Chromatography, High Pressure Liquid; DNA; DNA Methylation; Mice, Inbred C57BL; Tandem Mass Spectrometry | 2018 |
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Genetic Markers; Humans; Male; Microglia; Middle Aged; Neurons; Parahippocampal Gyrus | 2014 |
Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cytosine; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Humans; Ivermectin; Male; Methylation | 2014 |
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins | 2014 |
Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cytosine; DNA Methylation; Entorhinal Cortex; Epigenesis, Genetic; Female; Humans; Male; Middle Aged | 2015 |
TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer's disease hippocampus.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cytosine; DNA Methylation; Female; Genome-Wide Association Study; Hippocampus; Humans; Male; Membrane Glycoproteins; Middle Aged; Receptors, Immunologic; Up-Regulation | 2016 |
5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Autopsy; Disease Models, Animal; DNA Methylation; Drosophila melanogaster; Epigenesis, Genetic; Female; Gene Expression Regulation; Genome, Human; Humans; Male; Neurogenesis; Neurons; Polymorphism, Single Nucleotide; Prefrontal Cortex; Protein Interaction Mapping; tau Proteins | 2016 |
Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Genome-Wide Association Study; Humans; Mice; Mice, Transgenic | 2016 |
Neurofilament-labeled pyramidal neurons and astrocytes are deficient in DNA methylation marks in Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Biomarkers; DNA Methylation; Female; Humans; Immunohistochemistry; Intermediate Filaments; Male; Middle Aged; Neurofibrillary Tangles; Pyramidal Cells | 2016 |
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Epigenesis, Genetic; Female; Gas Chromatography-Mass Spectrometry; Humans; Male | 2017 |
The role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Humans; Translocation, Genetic | 2012 |
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.
Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hippocampus; Male; Mice; Mice, Inbred C57BL; Up-Regulation | 2012 |
Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.
Topics: 5-Methylcytosine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavioral Symptoms; Benzofurans; Cognition Disorders; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Presenilin-1; Quinolines; Space Perception; Stress, Psychological | 2013 |