5-hydroxydecanoate has been researched along with Reperfusion Injury in 41 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous clinical studies have shown that anisodamine could improve no-reflow phenomenon and prevent reperfusion arrhythmias, but whether this protective effect is related to the antagonism of the M-type cholinergic receptor or other potential mechanisms is uncertain." | 8.02 | Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel. ( Bai, S; Chen, T; Du, R; Er, L; Li, X; Wang, X; Wu, H; Zhang, L, 2021) |
| "To ascertain if levosimendan postconditioning can alleviate lung ischemia-reperfusion injury (LIRI) in rats." | 7.81 | Influence of levosimendan postconditioning on apoptosis of rat lung cells in a model of ischemia-reperfusion injury. ( Ge, S; Guo, Z; Liu, H; Shi, Y; Zhang, C, 2015) |
| " The present study examined whether or not cilostazol reduces the myocardial infarct size, and investigated its mechanism in a rabbit model of myocardial infarction." | 7.77 | Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels. ( Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y, 2011) |
| "We investigated the effects of administration of non-hypotensive doses of ATP-sensitive K+ channel (KATP) openers (nicorandil and bimakalim), and a specific mitochondrial KATP channel blocker (5-hydroxydecanoate) prior to and during coronary occlusion as well as prior to and during post-ischemic reperfusion on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 7.71 | Effects of administration of nicorandil or bimakalim prior to and during ischemia or reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and infarct size in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "Severe sustained ventricular tachyarrhythmias developed on reflow in the controls and in the 5-HD exposed hearts." | 5.32 | Effects of barium and 5-hydroxydecanoate on the electrophysiologic response to acute regional ischemia and reperfusion in rat hearts. ( Baiardi, G; Petrich, ER; Zumino, AP, 2003) |
| "Previous clinical studies have shown that anisodamine could improve no-reflow phenomenon and prevent reperfusion arrhythmias, but whether this protective effect is related to the antagonism of the M-type cholinergic receptor or other potential mechanisms is uncertain." | 4.02 | Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel. ( Bai, S; Chen, T; Du, R; Er, L; Li, X; Wang, X; Wu, H; Zhang, L, 2021) |
| "To ascertain if levosimendan postconditioning can alleviate lung ischemia-reperfusion injury (LIRI) in rats." | 3.81 | Influence of levosimendan postconditioning on apoptosis of rat lung cells in a model of ischemia-reperfusion injury. ( Ge, S; Guo, Z; Liu, H; Shi, Y; Zhang, C, 2015) |
| " The present study examined whether or not cilostazol reduces the myocardial infarct size, and investigated its mechanism in a rabbit model of myocardial infarction." | 3.77 | Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels. ( Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y, 2011) |
| " Seven minutes before hypoxia reoxygenation, muscles were exposed to 4 min of hypoxia and 7 min of reoxygenation or 15 min of sevoflurane at concentrations of 1, 2, and 3%." | 3.72 | Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro. ( Babatasi, G; Bricard, H; Ducouret, P; Gérard, JL; Haelewyn, B; Hanouz, JL; Khayat, A; Massetti, M; Terrien, X; Yvon, A, 2003) |
| "We investigated the effects of administration of non-hypotensive doses of ATP-sensitive K+ channel (KATP) openers (nicorandil and bimakalim), and a specific mitochondrial KATP channel blocker (5-hydroxydecanoate) prior to and during coronary occlusion as well as prior to and during post-ischemic reperfusion on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.71 | Effects of administration of nicorandil or bimakalim prior to and during ischemia or reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and infarct size in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "Rats were exposed to 90 minutes of middle cerebral artery occlusion followed by 72 hours of reperfusion." | 1.38 | Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury. ( Deng, J; Dong, H; Li, Y; Li, Z; Luan, Q; Sun, J; Tong, L; Xiong, L, 2012) |
| "Pretreatment with diazoxide, K(ATP) channel opener, increases tissue tolerance against ischemia reperfusion (IR) injury." | 1.38 | Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms. ( Ajami, M; Ebrahimi, SA; Habibey, R; Moghtadaei, M; Pazoki-Toroudi, H; Soleimani, M, 2012) |
| "Diazoxide treatment attenuated cytotoxicity in both cell types and 5-HD treatment-increased cytotoxicity in the sensitive NRK cells in a superoxide-dependant manner." | 1.36 | Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells. ( Johnson, CP; Liang, H; Mortensen, J; Nilakantan, V; Taylor, E, 2010) |
| "Treatment with sulforaphane inhibited an increase in the post-ischemic left ventricular end-diastolic pressure (LVEDP) and improved the post-ischemic left ventricular developed pressure (LVDP), +/-dP/dt, and coronary flow as compared with the untreated control hearts." | 1.36 | Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels. ( Chae, HJ; Chae, SW; Gao, S; Kim, DS; Kim, SH; Lee, GH; Park, BH; Piao, CS, 2010) |
| "Propofol treatments were initiated at various time intervals: 1 or 24 h before ischemia, only during ischemia, or only during reperfusion." | 1.35 | The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion. ( Assad, AR; Capella, MA; Delou, JM; Fonseca, LM; Lopes, AG; Nascimento, JH; Verçosa, N; Villela, NR, 2009) |
| "Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
| "Severe sustained ventricular tachyarrhythmias developed on reflow in the controls and in the 5-HD exposed hearts." | 1.32 | Effects of barium and 5-hydroxydecanoate on the electrophysiologic response to acute regional ischemia and reperfusion in rat hearts. ( Baiardi, G; Petrich, ER; Zumino, AP, 2003) |
| " In a first study to characterize effects of sex and the dose-response profile of estrogen on infarct size, the drug was intravenously administered at 10 or 20 microg/kg." | 1.31 | Cardioprotective effects of 17 beta-estradiol produced by activation ofmitochondrial ATP-sensitive K(+)Channels in canine hearts. ( Lee, TM; Lee, YT; Su, SF; Tsai, CC; Tsai, CH, 2000) |
| "This anti-infarction effect of IPC was blocked by Chel (42 +/- 7%) and Poly B (37 +/- 2%) and mimicked by PMA (19 +/- 10%) and OAG (14 +/- 5%) treatments (P < 0." | 1.31 | Role and mechanism of PKC in ischemic preconditioning of pig skeletal muscle against infarction. ( Forrest, CR; He, W; Hopper, RA; Neligan, P; Pang, CY; Rutka, J; Xu, H; Zhong, A, 2000) |
| "Diazoxide pretreatment significantly increased nuclear translocation of p65 which was blocked by protein kinase C (PKC) or nitric oxide synthase (NOS) inhibition." | 1.31 | Mitochondrial K(ATP) channel as an end effector of cardioprotection during late preconditioning: triggering role of nitric oxide. ( Ashraf, M; Ayub, A; Kudo, M; Wang, Y; Xu, M, 2001) |
| "Cromakalim (20 microM) was protective in this ischemic model and this was abolished by 5-HD." | 1.29 | The KATP blocker sodium 5-hydroxydecanoate does not abolish preconditioning in isolated rat hearts. ( Baird, AJ; Dzwonczyk, S; Grover, GJ; Murray, HN, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 20 (48.78) | 29.6817 |
| 2010's | 17 (41.46) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, S | 1 |
| Wang, X | 1 |
| Wu, H | 1 |
| Chen, T | 1 |
| Li, X | 2 |
| Zhang, L | 1 |
| Er, L | 1 |
| Du, R | 1 |
| Fukui, T | 1 |
| Ishida, K | 1 |
| Mizukami, Y | 1 |
| Shiramoto, K | 1 |
| Harada, H | 1 |
| Yamashita, A | 1 |
| Yamashita, S | 1 |
| Matsumoto, M | 1 |
| Abbas, SS | 1 |
| Mahmoud, HM | 1 |
| Schaalan, MF | 1 |
| El-Abhar, HS | 1 |
| Grossini, E | 2 |
| Pollesello, P | 2 |
| Bellofatto, K | 1 |
| Sigaudo, L | 1 |
| Farruggio, S | 1 |
| Origlia, V | 1 |
| Mombello, C | 1 |
| Mary, DA | 1 |
| Valente, G | 2 |
| Vacca, G | 2 |
| Shimizu, S | 1 |
| Oikawa, R | 1 |
| Tsounapi, P | 1 |
| Inoue, K | 1 |
| Shimizu, T | 1 |
| Tanaka, K | 1 |
| Martin, DT | 1 |
| Honda, M | 1 |
| Sejima, T | 1 |
| Tomita, S | 1 |
| Saito, M | 1 |
| Zhang, C | 1 |
| Guo, Z | 1 |
| Liu, H | 1 |
| Shi, Y | 1 |
| Ge, S | 1 |
| Mehrjerdi, FZ | 1 |
| Aboutaleb, N | 1 |
| Pazoki-Toroudi, H | 2 |
| Soleimani, M | 2 |
| Ajami, M | 2 |
| Khaksari, M | 1 |
| Safari, F | 1 |
| Habibey, R | 2 |
| Hao, J | 1 |
| Li, WW | 1 |
| Du, H | 1 |
| Zhao, ZF | 1 |
| Liu, F | 1 |
| Lu, JC | 1 |
| Yang, XC | 1 |
| Cui, W | 1 |
| Nilakantan, V | 1 |
| Liang, H | 1 |
| Mortensen, J | 1 |
| Taylor, E | 1 |
| Johnson, CP | 1 |
| Assad, AR | 1 |
| Delou, JM | 1 |
| Fonseca, LM | 1 |
| Villela, NR | 1 |
| Nascimento, JH | 1 |
| Verçosa, N | 1 |
| Lopes, AG | 1 |
| Capella, MA | 1 |
| Piao, CS | 1 |
| Gao, S | 1 |
| Lee, GH | 1 |
| Kim, DS | 1 |
| Park, BH | 1 |
| Chae, SW | 1 |
| Chae, HJ | 1 |
| Kim, SH | 1 |
| Iwasa, M | 3 |
| Kobayashi, H | 2 |
| Yasuda, S | 2 |
| Kawamura, I | 1 |
| Sumi, S | 3 |
| Yamada, Y | 3 |
| Shiraki, T | 1 |
| Yamaki, T | 2 |
| Ushikoshi, H | 3 |
| Aoyama, T | 3 |
| Nishigaki, K | 3 |
| Takemura, G | 3 |
| Fujiwara, T | 1 |
| Fujiwara, H | 1 |
| Minatoguchi, S | 3 |
| Hattori, A | 1 |
| Robin, E | 1 |
| Simerabet, M | 1 |
| Hassoun, SM | 1 |
| Adamczyk, S | 1 |
| Tavernier, B | 1 |
| Vallet, B | 1 |
| Bordet, R | 1 |
| Lebuffe, G | 1 |
| Bai, Y | 1 |
| Murakami, H | 1 |
| Uno, B | 1 |
| Sun, J | 1 |
| Tong, L | 1 |
| Luan, Q | 1 |
| Deng, J | 1 |
| Li, Y | 2 |
| Li, Z | 1 |
| Dong, H | 1 |
| Xiong, L | 1 |
| Molinari, C | 1 |
| Bellomo, G | 1 |
| Mary, D | 1 |
| Caimmi, P | 1 |
| Moghtadaei, M | 1 |
| Ebrahimi, SA | 1 |
| Talha, S | 1 |
| Bouitbir, J | 1 |
| Charles, AL | 1 |
| Zoll, J | 1 |
| Goette-Di Marco, P | 1 |
| Meziani, F | 1 |
| Piquard, F | 1 |
| Geny, B | 1 |
| Yvon, A | 1 |
| Hanouz, JL | 1 |
| Haelewyn, B | 1 |
| Terrien, X | 1 |
| Massetti, M | 1 |
| Babatasi, G | 1 |
| Khayat, A | 1 |
| Ducouret, P | 1 |
| Bricard, H | 1 |
| Gérard, JL | 1 |
| Clark, JE | 1 |
| Naughton, P | 1 |
| Shurey, S | 1 |
| Green, CJ | 1 |
| Johnson, TR | 1 |
| Mann, BE | 1 |
| Foresti, R | 1 |
| Motterlini, R | 1 |
| Zhu, HF | 1 |
| Dong, JW | 1 |
| Zhu, WZ | 1 |
| Ding, HL | 1 |
| Zhou, ZN | 1 |
| Baiardi, G | 1 |
| Zumino, AP | 1 |
| Petrich, ER | 1 |
| Kicińska, A | 1 |
| Szewczyk, A | 1 |
| Marina Prendes, MG | 1 |
| García, JV | 1 |
| Fernández, MA | 1 |
| Pérez, MJ | 1 |
| Perazzo, JC | 1 |
| Savino, EA | 1 |
| Varela, A | 1 |
| Roth, S | 1 |
| Dreixler, JC | 1 |
| Shaikh, AR | 1 |
| Lee, KH | 1 |
| Bindokas, V | 1 |
| Kandilci, HB | 1 |
| Gümüşel, B | 1 |
| Demiryürek, AT | 1 |
| Lippton, H | 1 |
| Gao, H | 1 |
| Chen, L | 1 |
| Yang, HT | 1 |
| Vajda, S | 1 |
| Baczkó, I | 1 |
| Leprán, I | 1 |
| Chen, Z | 1 |
| Li, T | 1 |
| Zhang, B | 1 |
| Lee, JJ | 1 |
| Li, L | 1 |
| Jung, HH | 1 |
| Zuo, Z | 1 |
| Grover, GJ | 1 |
| Murray, HN | 1 |
| Baird, AJ | 1 |
| Dzwonczyk, S | 1 |
| Awan, MM | 1 |
| Taunyane, C | 1 |
| Aitchison, KA | 1 |
| Yellon, DM | 1 |
| Opie, LH | 1 |
| Tanonaka, K | 1 |
| Taguchi, T | 1 |
| Koshimizu, M | 1 |
| Ando, T | 1 |
| Morinaka, T | 1 |
| Yogo, T | 1 |
| Konishi, F | 1 |
| Takeo, S | 1 |
| Vanden Hoek, T | 1 |
| Becker, LB | 1 |
| Shao, ZH | 1 |
| Li, CQ | 1 |
| Schumacker, PT | 1 |
| Lee, TM | 1 |
| Su, SF | 1 |
| Tsai, CC | 1 |
| Lee, YT | 1 |
| Tsai, CH | 1 |
| Hopper, RA | 1 |
| Forrest, CR | 1 |
| Xu, H | 1 |
| Zhong, A | 1 |
| He, W | 1 |
| Rutka, J | 1 |
| Neligan, P | 1 |
| Pang, CY | 1 |
| Tanhehco, EJ | 1 |
| Yasojima, K | 1 |
| McGeer, PL | 1 |
| McGeer, EG | 1 |
| Lucchesi, BR | 1 |
| Das, B | 1 |
| Sarkar, C | 1 |
| Karanth, KS | 1 |
| Wang, Y | 1 |
| Kudo, M | 1 |
| Xu, M | 1 |
| Ayub, A | 1 |
| Ashraf, M | 1 |
| Sato, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
41 other studies available for 5-hydroxydecanoate and Reperfusion Injury
| Article | Year |
|---|---|
Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Decanoic Acids; Energy Me | 2021 |
Comparison of the protective effects of direct ischemic preconditioning and remote ischemic preconditioning in a rabbit model of transient spinal cord ischemia.
Topics: Animals; Decanoic Acids; Extremities; Hydroxy Acids; Ischemic Preconditioning; Kidney; Male; Rabbits | 2018 |
Involvement of brain natriuretic peptide signaling pathway in the cardioprotective action of sitagliptin.
Topics: Animals; bcl-2-Associated X Protein; Carbazoles; Cardiotonic Agents; Caspase 3; Cyclic GMP; Cyclophi | 2018 |
Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats.
Topics: Anesthesia; Animals; Apoptosis; bcl-2-Associated X Protein; Biopsy; Blood Flow Velocity; Caspase 3; | 2014 |
Blocking of the ATP sensitive potassium channel ameliorates the ischaemia-reperfusion injury in the rat testis.
Topics: Animals; Apoptosis; Cromakalim; Decanoic Acids; Diazoxide; Glyburide; Hydroxy Acids; KATP Channels; | 2014 |
Influence of levosimendan postconditioning on apoptosis of rat lung cells in a model of ischemia-reperfusion injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Caspase 3; Decanoic Acids; Disea | 2015 |
The Protective Effect of Remote Renal Preconditioning Against Hippocampal Ischemia Reperfusion Injury: Role of KATP Channels.
Topics: Animals; Apoptosis; Catalase; Decanoic Acids; Glyburide; Hippocampus; Hydroxy Acids; Ischemic Precon | 2015 |
Role of Vitamin C in Cardioprotection of Ischemia/Reperfusion Injury by Activation of Mitochondrial KATP Channel.
Topics: Animals; Ascorbic Acid; Cardiotonic Agents; Decanoic Acids; Hydroxy Acids; Indazoles; Male; Mitochon | 2016 |
Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Epithelial Cells; Hydroxy Acids; Kidney; | 2010 |
The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Apoptosis; Cell Survival; Cytoprotection; Decanoic Aci | 2009 |
Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels.
Topics: Animals; Antioxidants; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Caspase 3; Decanoic Ac | 2010 |
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
Topics: alpha-Glucosidases; Animals; Arginine; Decanoic Acids; Glucagon-Like Peptide 1; Glucagon-Like Peptid | 2010 |
Postconditioning effect of granulocyte colony-stimulating factor is mediated through activation of risk pathway and opening of the mitochondrial KATP channels.
Topics: Androstadienes; Animals; Decanoic Acids; Extracellular Signal-Regulated MAP Kinases; Glycogen Syntha | 2010 |
Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel.
Topics: Animals; Behavior, Animal; Brain Ischemia; Calcium; Decanoic Acids; Hydroxy Acids; Infarction, Middl | 2011 |
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Eva | 2011 |
Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Apoptosis; Brain Diseases; Decanoic Acids; Hydroxy Acids; Infarctio | 2012 |
Levosimendan protection against kidney ischemia/reperfusion injuries in anesthetized pigs.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Survival; Decanoic Acids; Glucose; Hydra | 2012 |
Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Catalase; Cell Nucleus; Decanoic Acids; Diazoxide; H | 2012 |
Pretreatment with brain natriuretic peptide reduces skeletal muscle mitochondrial dysfunction and oxidative stress after ischemia-reperfusion.
Topics: Animals; Apoptosis; Caspase 3; Decanoic Acids; Electron Transport; Hydroxy Acids; KATP Channels; Mal | 2013 |
Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro.
Topics: Aged; Anesthetics, Inhalation; ATP-Binding Cassette Transporters; Benzamides; Decanoic Acids; Heart | 2003 |
Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule.
Topics: Animals; Carbon Monoxide; Cardiotonic Agents; Cells, Cultured; Decanoic Acids; Disease Models, Anima | 2003 |
ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Calcium; Decanoic Acids; Glyburide; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hypoxia; | 2003 |
Effects of barium and 5-hydroxydecanoate on the electrophysiologic response to acute regional ischemia and reperfusion in rat hearts.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Barium; Decanoic Acids; Electroencephalography; | 2003 |
Protective effects of the potassium channel opener-diazoxide against injury in neonatal rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Cardiotonic Agents; Cell Line; Decanoic Acids; Diazoxide; Dose | 2003 |
Effects of 5-hydroxydecanoate and ischemic preconditioning on the ischemic-reperfused heart of fed and fasted rats.
Topics: Animals; Decanoic Acids; Fasting; Female; Heart; Hydroxy Acids; Ischemic Preconditioning; Male; Rats | 2005 |
Mitochondrial potassium ATP channels and retinal ischemic preconditioning.
Topics: Animals; Decanoic Acids; Diazoxide; Electroretinography; Fluorescent Antibody Technique, Indirect; H | 2006 |
Preconditioning modulates pulmonary endothelial dysfunction following ischemia-reperfusion injury in the rat lung: role of potassium channels.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Benzamides; Decanoic Acids; Endothelium, Vascular; G | 2006 |
Activation of alpha1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes.
Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anima | 2007 |
Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Anesthesia; Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Blood Pressure | 2007 |
Morphine postconditioning protects against reperfusion injury in the isolated rat hearts.
Topics: Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic Acids; Dose-Respon | 2008 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |
The KATP blocker sodium 5-hydroxydecanoate does not abolish preconditioning in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzopyrans; Blood Pressure; Coronary Circu | 1995 |
Normothermic transfer times up to 3 min will not precondition the isolated rat heart.
Topics: Animals; Decanoic Acids; Heart Rate; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Orga | 1999 |
Role of an ATP-sensitive potassium channel opener, YM934, in mitochondrial energy production in ischemic/reperfused heart.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzoxazines; Creatine Kinase; Cyclic N-Oxi | 1999 |
Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Cell Death; Cells, Cultured; Chick Embryo; Decanoic Acids; Hydrogen | 2000 |
Cardioprotective effects of 17 beta-estradiol produced by activation ofmitochondrial ATP-sensitive K(+)Channels in canine hearts.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Decanoic Acids; Dogs; | 2000 |
Role and mechanism of PKC in ischemic preconditioning of pig skeletal muscle against infarction.
Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Decanoic Acids; Diglyceri | 2000 |
Preconditioning reduces myocardial complement gene expression in vivo.
Topics: Animals; Anti-Arrhythmia Agents; Blotting, Western; Complement System Proteins; Decanoic Acids; Diaz | 2000 |
Effects of administration of nicorandil or bimakalim prior to and during ischemia or reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and infarct size in anesthetized rabbits.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Blood Gas Analysis; Coronary Di | 2001 |
Mitochondrial K(ATP) channel as an end effector of cardioprotection during late preconditioning: triggering role of nitric oxide.
Topics: Acetophenones; Active Transport, Cell Nucleus; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agen | 2001 |
Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Benzophenanthridines; Blotting, Western; Bradykinin; Dec | 2001 |