5-hydroxydecanoate has been researched along with Nerve Degeneration in 4 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The number of FJ-positive degenerating neurons in the CA1 area of the hippocampus, the cerebellum and the thalamic reticular nucleus of the ketogenic diet-fed rats with or without glibenclamide or 5-hydroxydecanoate pre-treatment before cardiac arrest-induced cerebral ischemia is zero." | 3.75 | Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration. ( Pham, L; Tai, KK; Truong, DD, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nam, YJ | 1 |
| Lee, DH | 1 |
| Lee, MS | 1 |
| Lee, CS | 2 |
| Yang, YJ | 1 |
| Zhang, S | 1 |
| Ding, JH | 1 |
| Zhou, F | 1 |
| Hu, G | 1 |
| Tai, KK | 1 |
| Pham, L | 1 |
| Truong, DD | 1 |
| Kim, YJ | 1 |
| Ko, HH | 1 |
| Han, ES | 1 |
4 other studies available for 5-hydroxydecanoate and Nerve Degeneration
| Article | Year |
|---|---|
K(ATP) channel block prevents proteasome inhibitor-induced apoptosis in differentiated PC12 cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Decanoic Acids; Dose-Response Relationship, Drug; | 2015 |
Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Brain Stem | 2009 |
Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.
Topics: Animals; Brain Ischemia; Decanoic Acids; Diet, Ketogenic; Fluoresceins; Glyburide; Heart Arrest; Hyd | 2009 |
Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Caspase 3; Cell Death; Cell Membrane Permeability; Cell Nucleu | 2007 |