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5-hydroxydecanoate and Nerve Degeneration

5-hydroxydecanoate has been researched along with Nerve Degeneration in 4 studies

5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"The number of FJ-positive degenerating neurons in the CA1 area of the hippocampus, the cerebellum and the thalamic reticular nucleus of the ketogenic diet-fed rats with or without glibenclamide or 5-hydroxydecanoate pre-treatment before cardiac arrest-induced cerebral ischemia is zero."3.75Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration. ( Pham, L; Tai, KK; Truong, DD, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nam, YJ1
Lee, DH1
Lee, MS1
Lee, CS2
Yang, YJ1
Zhang, S1
Ding, JH1
Zhou, F1
Hu, G1
Tai, KK1
Pham, L1
Truong, DD1
Kim, YJ1
Ko, HH1
Han, ES1

Other Studies

4 other studies available for 5-hydroxydecanoate and Nerve Degeneration

ArticleYear
K(ATP) channel block prevents proteasome inhibitor-induced apoptosis in differentiated PC12 cells.
    European journal of pharmacology, 2015, 10-05, Volume: 764

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Decanoic Acids; Dose-Response Relationship, Drug;

2015
Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Brain Stem

2009
Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.
    Brain injury, 2009, Volume: 23, Issue:13-14

    Topics: Animals; Brain Ischemia; Decanoic Acids; Diet, Ketogenic; Fluoresceins; Glyburide; Heart Arrest; Hyd

2009
Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.
    Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Caspase 3; Cell Death; Cell Membrane Permeability; Cell Nucleu

2007