5-hydroxydecanoate has been researched along with Injury, Myocardial Reperfusion in 99 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous clinical studies have shown that anisodamine could improve no-reflow phenomenon and prevent reperfusion arrhythmias, but whether this protective effect is related to the antagonism of the M-type cholinergic receptor or other potential mechanisms is uncertain." | 8.02 | Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel. ( Bai, S; Chen, T; Du, R; Er, L; Li, X; Wang, X; Wu, H; Zhang, L, 2021) |
| "The aim of the current study was to determine whether hypercholesterolemia affects the delayed sevoflurane preconditioning against myocardial ischemia-reperfusion (IR) injury and, if so, the underlying mechanism." | 7.78 | Hypercholesterolemia abrogates sevoflurane-induced delayed preconditioning against myocardial infarct in rats by alteration of nitric oxide synthase signaling. ( Chen, G; Ma, LL; Qian, LB; Wang, WN; Yan, M; Yang, MJ; Yu, J; Yu, LN; Zhang, FJ, 2012) |
| "The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the effects could be mediated by mitochondrial ATP-sensitive potassium (m-KATP) channels." | 7.78 | High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels. ( Cho, S; Higashijima, U; Ichinomiya, T; Maekawa, T; Matsumoto, S; Sumikawa, K, 2012) |
| "The insulin-sensitizing drug pioglitazone has been reported to be protective against myocardial infarction." | 7.75 | Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction. ( Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nagashima, K; Narentuoya, B; Nishigaki, K; Sumi, S; Takemura, G; Ushikoshi, H; Yamaki, T; Yasuda, S, 2009) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 7.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| " In the present study, we investigated the effects of the administration of non-hypotensive doses of ATP-sensitive K+ channel (KATP) openers (nicorandil and 3-pyridyl pinacidil), a specific mitochondrial KATP channel blocker (5-hydroxydecanoate) and a specific sarcolemmal KATP channel blocker (HMR 1883; 1-[5-[2-(5-chloro-o-anisamido)ethyl]-2-methoxyphenyl]sulfonyl-3- methylthiourea) prior to and during coronary occlusion, as well as prior to and during post-ischemic reperfusion, on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 7.72 | Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion. ( Das, B; Sarkar, C, 2003) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 5.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| "In anesthetized rats, reperfusion arrhythmias were induced by occluding the left main coronary artery for 5 min and subsequent reperfusion." | 5.30 | Suppression of reperfusion arrhythmias by preconditioning is inhibited by an ATP-sensitive potassium channel blocker, 5-hydroxydecanoate, but not by protein kinase C blockers in the rat. ( Hasegawa, T; Kita, H; Miura, T; Shimamoto, K; Tsuchida, A, 1998) |
| "Previous clinical studies have shown that anisodamine could improve no-reflow phenomenon and prevent reperfusion arrhythmias, but whether this protective effect is related to the antagonism of the M-type cholinergic receptor or other potential mechanisms is uncertain." | 4.02 | Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel. ( Bai, S; Chen, T; Du, R; Er, L; Li, X; Wang, X; Wu, H; Zhang, L, 2021) |
| "The aim of the current study was to determine whether hypercholesterolemia affects the delayed sevoflurane preconditioning against myocardial ischemia-reperfusion (IR) injury and, if so, the underlying mechanism." | 3.78 | Hypercholesterolemia abrogates sevoflurane-induced delayed preconditioning against myocardial infarct in rats by alteration of nitric oxide synthase signaling. ( Chen, G; Ma, LL; Qian, LB; Wang, WN; Yan, M; Yang, MJ; Yu, J; Yu, LN; Zhang, FJ, 2012) |
| "The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the effects could be mediated by mitochondrial ATP-sensitive potassium (m-KATP) channels." | 3.78 | High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels. ( Cho, S; Higashijima, U; Ichinomiya, T; Maekawa, T; Matsumoto, S; Sumikawa, K, 2012) |
| " Compared with the IR-control group, both the LIPC and MIPC groups showed an amelioration of ventricular arrhythmia, reduced myocardial infarct size, increased activities of total superoxide dismutase, manganese-superoxide dismutase (Mn-SOD) and glutathione peroxidase, increased expression of Mn-SOD mRNA and decreased xanthine oxidase activity and malondialdehyde concentration." | 3.77 | Noninvasive delayed limb ischemic preconditioning attenuates myocardial ischemia-reperfusion injury in rats by a mitochondrial K(ATP) channel-dependent mechanism. ( Gao, WZ; Jiao, JJ; Kang, Y; Liu, YX; Lou, JS; Wu, YN; Yu, H; Yuan, HJ; Zhu, XH, 2011) |
| "The insulin-sensitizing drug pioglitazone has been reported to be protective against myocardial infarction." | 3.75 | Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction. ( Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nagashima, K; Narentuoya, B; Nishigaki, K; Sumi, S; Takemura, G; Ushikoshi, H; Yamaki, T; Yasuda, S, 2009) |
| "In the present study, we investigated the efficacy of pharmacological postconditioning induced by 17beta-estradiol and the phytoestrogen, genistein, against myocardial infarction induced by increasing durations of coronary artery occlusion (CAO)." | 3.75 | The ceiling effect of pharmacological postconditioning with the phytoestrogen genistein is reversed by the GSK3beta inhibitor SB 216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione] through mitochondrial ATP-dependent potassium c ( Berdeaux, A; Chenoune, M; Couvreur, N; Ghaleh, B; Pons, S; Tissier, R; Waintraub, X, 2009) |
| " Here, we have assessed its effects on ischaemia- and reperfusion-induced ventricular arrhythmias in vivo and a possible role for mitochondrial K(ATP) channels in these effects, using the channel inhibitor 5-hydroxydecanoate (5-HD)." | 3.74 | Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels. ( Huliák, I; Juhász, L; Kiss, A; Végh, A, 2008) |
| " In the present study, we sought to investigate the effects of administration of ATP-sensitive K(+) channel (K(ATP)) openers (nicorandil and minoxidil), a specific mitochondrial K(ATP) channel blocker (5-hydroxydecanoate (5-HD)) and a specific sarcolemmal K(ATP) channel blocker (HMR 1883; (1-[5-[2-(5-chloro-o-anisamido)ethyl]-2-methoxyphenyl]sulfonyl-3-methylthiourea) prior to coronary occlusion as well as prior to post-ischemic reperfusion on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.73 | Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model? ( Das, B; Sarkar, C, 2005) |
| "We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 3.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
| " In the present study, we investigated the effects of the administration of non-hypotensive doses of ATP-sensitive K+ channel (KATP) openers (nicorandil and 3-pyridyl pinacidil), a specific mitochondrial KATP channel blocker (5-hydroxydecanoate) and a specific sarcolemmal KATP channel blocker (HMR 1883; 1-[5-[2-(5-chloro-o-anisamido)ethyl]-2-methoxyphenyl]sulfonyl-3- methylthiourea) prior to and during coronary occlusion, as well as prior to and during post-ischemic reperfusion, on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.72 | Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion. ( Das, B; Sarkar, C, 2003) |
| " In the present study, we investigated the effects of administration of non-hypotensive doses of ATP-sensitive K(+) channel (K(ATP)) openers (nicorandil and cromakalim), a specific mitochondrial K(ATP) channel blocker (5-hydroxydecanoate (5-HD)) and a specific sarcolemmal K(ATP) channel blocker (HMR 1883; (1-[5-[2-(5-chloro-o-anisamido)ethyl]-2-methoxyphenyl]sulfonyl-3-methylthiourea) prior to and during coronary occlusion as well as prior to and during post-ischemic reperfusion on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.72 | Mitochondrial K ATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model. ( Das, B; Sarkar, C, 2003) |
| "We investigated the effects of administration of non-hypotensive doses of ATP-sensitive K+ channel (K(ATP)) openers (nicorandil and aprikalim), and a specific mitochondrial K(ATP) channel blocker (5-hydroxydecanoate) prior to and during coronary occlusion as well as prior to and during post-ischemic reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.71 | Selective mitochondrial K(ATP) channel activation results in antiarrhythmic effect during experimental myocardial ischemia/reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2002) |
| " Inhibition of mitochondrial K(ATP)channels with 5-hydroxydecanoate had no effect on baseline LVDP, LVEDP, or coronary flow but abolished the beneficial effects of alcohol on LV contractile recovery and myocyte necrosis." | 3.70 | Chronic ethanol-induced myocardial protection requires activation of mitochondrial K(ATP) channels. ( Gray, MO; Zhou, HZ; Zhu, P, 2000) |
| "Arrhythmias were assessed based on the Lambeth convention and were categorized as number, duration and incidence of ventricular tachycardia (VT), ventricular fibrillation (VF), and premature ventricular complexes (PVC), and arrhythmic score." | 1.40 | Anti-arrhythmic effect of diosgenin in reperfusion-induced myocardial injury in a rat model: activation of nitric oxide system and mitochondrial KATP channel. ( Badalzadeh, R; Ebrahimi, H; Majidinia, M; Yousefi, B, 2014) |
| "Myocardial infarction was initiated by permanent ligation of the left anterior descending (LAD) coronary artery." | 1.40 | Dodecafluoropentane emulsion elicits cardiac protection against myocardial infarction through an ATP-Sensitive K+ channel dependent mechanism. ( Chen, QM; Larson, DF; Strom, J; Swyers, T; Unger, E; Wilson, D, 2014) |
| "Oxytocin (OXT) pretreatment protects the heart during ischemia-reperfusion injury by activating ATP-dependent potassium (K(ATP)) channels." | 1.38 | Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart? ( Das, B; Sarkar, C, 2012) |
| "Desflurane (6%) was administered during the first 5 min of reoxygenation either alone or in the presence of calphostin C (PKC inhibitor) or 5-hydroxydecanoate (5-HD) (mitoK(ATP) channel antagonist)." | 1.37 | Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes. ( Buléon, C; Galera, P; Gérard, JL; Hanouz, JL; Lemoine, S; Massetti, M; Zhu, L, 2011) |
| "Atpenin A5 (AA5) is a potent and specific complex II inhibitor, and herein we report that AA5 (1 nM) also activates the mK(ATP) channel and protects against simulated ischemia-reperfusion (IR) injury in isolated cardiomyocytes." | 1.35 | The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels. ( Brookes, PS; Wojtovich, AP, 2009) |
| "Hydrogen sulfide (H2S) is a gaseous mediator, produced by the metabolic pathways that regulate tissue concentrations of sulfur-containing amino acids." | 1.33 | Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels. ( Baxter, GF; Johansen, D; Ytrehus, K, 2006) |
| "Cardiac hypertrophy has been demonstrated to decreases the ATP-sensitive potassium channels (K(ATP)), the major protective mechanism following the energy depletion, a common condition seen during the reperfusion after open heart surgery." | 1.32 | Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels. ( Maeda, H; Rajesh, KG; Sasaguri, S; Suzuki, R; Xing, Y, 2004) |
| "Control animals had an average arrhythmia score of 10." | 1.31 | Opioid-induced cardioprotection against myocardial infarction and arrhythmias: mitochondrial versus sarcolemmal ATP-sensitive potassium channels. ( Fryer, RM; Gross, GJ; Hsu, AK; Nagase, H, 2000) |
| "Pretreatment with diazoxide (100 microM) with a 10-min washout period reduced %IS/LV to 7." | 1.31 | Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction. ( Genda, S; Kuno, A; Matsumoto, T; Miki, T; Miura, T; Nozawa, Y; Shimamoto, K; Tanno, M; Tsuchida, A, 2001) |
| "In anesthetized rats, reperfusion arrhythmias were induced by occluding the left main coronary artery for 5 min and subsequent reperfusion." | 1.30 | Suppression of reperfusion arrhythmias by preconditioning is inhibited by an ATP-sensitive potassium channel blocker, 5-hydroxydecanoate, but not by protein kinase C blockers in the rat. ( Hasegawa, T; Kita, H; Miura, T; Shimamoto, K; Tsuchida, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (9.09) | 18.2507 |
| 2000's | 63 (63.64) | 29.6817 |
| 2010's | 26 (26.26) | 24.3611 |
| 2020's | 1 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Bulion, VV | 1 |
| Selina, EN | 1 |
| Krylova, IB | 1 |
| Bai, S | 1 |
| Wang, X | 2 |
| Wu, H | 1 |
| Chen, T | 1 |
| Li, X | 2 |
| Zhang, L | 1 |
| Er, L | 1 |
| Du, R | 1 |
| Yokoyama, S | 1 |
| Nakagawa, I | 1 |
| Ogawa, Y | 1 |
| Morisaki, Y | 1 |
| Motoyama, Y | 1 |
| Park, YS | 1 |
| Saito, Y | 1 |
| Nakase, H | 1 |
| Shimanskaia, TV | 1 |
| Strutinskaia, NA | 1 |
| Vavilova, GL | 1 |
| Goshovskaia, IuV | 1 |
| Semenikhina, EN | 1 |
| Sagach, VF | 1 |
| Wang, J | 2 |
| Takahashi, K | 1 |
| Piao, H | 1 |
| Qu, P | 1 |
| Naruse, K | 1 |
| Prendes, MG | 1 |
| Hermann, R | 1 |
| Torresin, ME | 1 |
| Vélez, D | 1 |
| Savino, EA | 1 |
| Varela, A | 1 |
| Badalzadeh, R | 1 |
| Yousefi, B | 1 |
| Majidinia, M | 1 |
| Ebrahimi, H | 1 |
| Strom, J | 1 |
| Swyers, T | 1 |
| Wilson, D | 1 |
| Unger, E | 1 |
| Chen, QM | 1 |
| Larson, DF | 1 |
| Wang, C | 1 |
| Hu, SM | 1 |
| Xie, H | 1 |
| Qiao, SG | 1 |
| Liu, H | 1 |
| Liu, CF | 1 |
| Bu, HM | 1 |
| Yang, CY | 1 |
| Wang, ML | 1 |
| Ma, HJ | 2 |
| Sun, H | 1 |
| Zhang, Y | 4 |
| Imani, A | 1 |
| Khansari, M | 1 |
| Azizi, Y | 1 |
| Rakhshan, K | 1 |
| Faghihi, M | 1 |
| Donato, M | 1 |
| Goyeneche, MA | 1 |
| Garces, M | 1 |
| Marchini, T | 1 |
| Pérez, V | 1 |
| Del Mauro, J | 1 |
| Höcht, C | 1 |
| Rodríguez, M | 1 |
| Evelson, P | 1 |
| Gelpi, RJ | 1 |
| Meng, LM | 1 |
| Guo, H | 1 |
| Kong, QQ | 1 |
| Sivarajah, A | 2 |
| Collino, M | 1 |
| Yasin, M | 1 |
| Benetti, E | 1 |
| Gallicchio, M | 1 |
| Mazzon, E | 1 |
| Cuzzocrea, S | 1 |
| Fantozzi, R | 1 |
| Thiemermann, C | 5 |
| Kiss, A | 1 |
| Juhász, L | 1 |
| Huliák, I | 1 |
| Végh, A | 2 |
| Strutyns'kyĭ, RB | 1 |
| Pyvovar, SM | 1 |
| Tumanovs'ka, LV | 1 |
| Moĭbenko, OO | 1 |
| Wojtovich, AP | 1 |
| Brookes, PS | 1 |
| Maslov, LN | 2 |
| Lishmanov, YB | 1 |
| Oeltgen, PR | 1 |
| Barzakh, EI | 2 |
| Krylatov, AV | 2 |
| Govindaswami, M | 1 |
| Brown, SA | 1 |
| Yasuda, S | 1 |
| Kobayashi, H | 1 |
| Iwasa, M | 1 |
| Kawamura, I | 1 |
| Sumi, S | 1 |
| Narentuoya, B | 1 |
| Yamaki, T | 1 |
| Ushikoshi, H | 1 |
| Nishigaki, K | 1 |
| Nagashima, K | 1 |
| Takemura, G | 2 |
| Fujiwara, T | 1 |
| Fujiwara, H | 2 |
| Minatoguchi, S | 2 |
| Couvreur, N | 1 |
| Tissier, R | 1 |
| Pons, S | 1 |
| Chenoune, M | 1 |
| Waintraub, X | 1 |
| Berdeaux, A | 1 |
| Ghaleh, B | 1 |
| Quindry, JC | 2 |
| Schreiber, L | 1 |
| Hosick, P | 1 |
| Wrieden, J | 1 |
| Irwin, JM | 2 |
| Hoyt, E | 1 |
| Panneerselvam, M | 1 |
| Tsutsumi, YM | 1 |
| Bonds, JA | 1 |
| Horikawa, YT | 1 |
| Saldana, M | 1 |
| Dalton, ND | 1 |
| Head, BP | 1 |
| Patel, PM | 1 |
| Roth, DM | 1 |
| Patel, HH | 1 |
| Wu, YN | 1 |
| Yu, H | 1 |
| Zhu, XH | 1 |
| Yuan, HJ | 1 |
| Kang, Y | 1 |
| Jiao, JJ | 1 |
| Gao, WZ | 1 |
| Liu, YX | 1 |
| Lou, JS | 1 |
| Pan, HY | 2 |
| Gao, Q | 3 |
| Yao, H | 1 |
| Xia, Q | 4 |
| Chernysheva, GA | 1 |
| Krieg, T | 1 |
| Solenkova, NV | 1 |
| Lishmanov, AY | 1 |
| Cybulnikov, SY | 1 |
| Nuñez, IP | 1 |
| Fantinelli, J | 1 |
| Arbeláez, LF | 1 |
| Mosca, SM | 2 |
| Ma, H | 1 |
| Huang, X | 1 |
| Li, Q | 2 |
| Guan, Y | 1 |
| Yuan, F | 1 |
| Lemoine, S | 1 |
| Zhu, L | 1 |
| Buléon, C | 1 |
| Massetti, M | 1 |
| Gérard, JL | 1 |
| Galera, P | 1 |
| Hanouz, JL | 1 |
| Zhang, FJ | 1 |
| Ma, LL | 1 |
| Wang, WN | 1 |
| Qian, LB | 1 |
| Yang, MJ | 1 |
| Yu, J | 1 |
| Chen, G | 1 |
| Yu, LN | 1 |
| Yan, M | 1 |
| Ichinomiya, T | 1 |
| Cho, S | 1 |
| Higashijima, U | 1 |
| Matsumoto, S | 1 |
| Maekawa, T | 1 |
| Sumikawa, K | 1 |
| Das, B | 5 |
| Sarkar, C | 5 |
| Yoshida, A | 1 |
| Asanuma, H | 2 |
| Sasaki, H | 1 |
| Sanada, S | 2 |
| Yamazaki, S | 1 |
| Asano, Y | 1 |
| Shinozaki, Y | 2 |
| Mori, H | 2 |
| Shimouchi, A | 1 |
| Sano, M | 1 |
| Asakura, M | 2 |
| Minamino, T | 1 |
| Takashima, S | 2 |
| Sugimachi, M | 1 |
| Mochizuki, N | 1 |
| Kitakaze, M | 2 |
| Miller, L | 1 |
| McGinnis, G | 1 |
| Kliszczewicz, B | 1 |
| Landram, M | 1 |
| Urbiztondo, Z | 1 |
| Nanayakkara, G | 1 |
| Amin, R | 1 |
| Gross, GJ | 4 |
| Hsu, A | 1 |
| Nithipatikom, K | 1 |
| Pfeiffer, AW | 1 |
| Bobrova, I | 1 |
| Bissessar, E | 1 |
| Lian, C | 1 |
| Zhou, R | 1 |
| Li, T | 1 |
| Xiang, X | 1 |
| Liu, B | 1 |
| Hausenloy, DJ | 1 |
| Maddock, HL | 1 |
| Baxter, GF | 2 |
| Yellon, DM | 1 |
| Schwartz, LM | 1 |
| Welch, TS | 1 |
| Crago, MS | 1 |
| Parratt, JR | 1 |
| Headrick, JP | 2 |
| Willems, L | 1 |
| Ashton, KJ | 1 |
| Holmgren, K | 1 |
| Peart, J | 1 |
| Matherne, GP | 2 |
| Chen, X | 1 |
| Wang, N | 1 |
| Arai, M | 1 |
| Lu, C | 1 |
| Uno, Y | 1 |
| Misao, Y | 1 |
| Ala-Rämi, A | 1 |
| Ylitalo, KV | 1 |
| Hassinen, IE | 1 |
| Jones, SP | 1 |
| Greer, JJ | 1 |
| Kakkar, AK | 1 |
| Ware, PD | 1 |
| Turnage, RH | 1 |
| Hicks, M | 1 |
| van Haperen, R | 1 |
| de Crom, R | 1 |
| Kawashima, S | 1 |
| Yokoyama, M | 1 |
| Lefer, DJ | 1 |
| Shen, YL | 1 |
| Chen, YY | 2 |
| Wu, XD | 1 |
| Bruce, IC | 2 |
| Rajesh, KG | 1 |
| Sasaguri, S | 1 |
| Suzuki, R | 1 |
| Xing, Y | 1 |
| Maeda, H | 1 |
| Cao, CM | 1 |
| Chen, M | 1 |
| Wong, TM | 1 |
| Sarre, A | 1 |
| Lange, N | 1 |
| Kucera, P | 1 |
| Raddatz, E | 1 |
| Kimura, S | 1 |
| Zhang, GX | 1 |
| Nishiyama, A | 1 |
| Shokoji, T | 1 |
| Yao, L | 1 |
| Fan, YY | 1 |
| Rahman, M | 1 |
| Suzuki, T | 1 |
| Maeta, H | 1 |
| Abe, Y | 1 |
| Zhu, YH | 1 |
| Brown, DA | 1 |
| Chicco, AJ | 1 |
| Jew, KN | 1 |
| Johnson, MS | 1 |
| Lynch, JM | 1 |
| Watson, PA | 1 |
| Moore, RL | 1 |
| Yoshida, H | 1 |
| Kusama, Y | 1 |
| Kodani, E | 1 |
| Yasutake, M | 1 |
| Takano, H | 1 |
| Atarashi, H | 1 |
| Kishida, H | 1 |
| Takano, T | 1 |
| Johansen, D | 1 |
| Ytrehus, K | 1 |
| Masui, K | 1 |
| Kashimoto, S | 1 |
| Furuya, A | 1 |
| Oguchi, T | 1 |
| Joyeux-Faure, M | 1 |
| Ramond, A | 1 |
| Béguin, PC | 1 |
| Belaïdi, E | 1 |
| Godin-Ribuot, D | 1 |
| Ribuot, C | 1 |
| Qiu, S | 1 |
| Lu, Y | 1 |
| Luo, JH | 1 |
| Gok, S | 2 |
| Vural, K | 2 |
| Sekuri, C | 2 |
| Onur, R | 1 |
| Tezcan, A | 2 |
| Izanli, A | 2 |
| Vatansever, S | 1 |
| Cilaker, S | 1 |
| Obata, T | 1 |
| McDonald, MC | 1 |
| Lu, J | 1 |
| Zang, WJ | 1 |
| Yu, XJ | 1 |
| Jia, B | 1 |
| Chorvatova, A | 1 |
| Sun, L | 1 |
| Katakam, PV | 1 |
| Jordan, JE | 1 |
| Snipes, JA | 1 |
| Tulbert, CD | 1 |
| Miller, AW | 1 |
| Busija, DW | 1 |
| Xu, D | 1 |
| Li, Y | 2 |
| Davey, AK | 1 |
| Zhang, S | 1 |
| Evans, AM | 1 |
| Shinohara, T | 1 |
| Takahashi, N | 1 |
| Kohno, H | 1 |
| Yamanaka, K | 1 |
| Ooie, T | 1 |
| Wakisaka, O | 1 |
| Murozono, Y | 1 |
| Taniguchi, Y | 1 |
| Torigoe, Y | 1 |
| Hara, M | 1 |
| Shimada, T | 1 |
| Saikawa, T | 1 |
| Yoshimatsu, H | 1 |
| Chen, CH | 1 |
| Liu, K | 1 |
| Chan, JY | 1 |
| Rodrigo, GC | 1 |
| Samani, NJ | 1 |
| Colantuono, G | 1 |
| Tiravanti, EA | 1 |
| Di Venosa, N | 1 |
| Cazzato, A | 1 |
| Rastaldo, R | 1 |
| Cagiano, R | 1 |
| D'Agostino, D | 1 |
| Federici, A | 1 |
| Fiore, T | 1 |
| Zheng, MZ | 1 |
| Jiang, JP | 1 |
| Lucchinetti, E | 1 |
| Jamnicki, M | 1 |
| Fischer, G | 1 |
| Zaugg, M | 1 |
| Kaneda, K | 1 |
| Miyamae, M | 1 |
| Sugioka, S | 1 |
| Okusa, C | 1 |
| Inamura, Y | 1 |
| Domae, N | 1 |
| Kotani, J | 1 |
| Figueredo, VM | 1 |
| Matejíková, J | 1 |
| Kucharská, J | 1 |
| Pintérová, M | 1 |
| Pancza, D | 1 |
| Ravingerová, T | 1 |
| Pasdois, P | 1 |
| Beauvoit, B | 1 |
| Tariosse, L | 1 |
| Vinassa, B | 1 |
| Bonoron-Adèle, S | 1 |
| Dos Santos, P | 1 |
| Lee, SH | 1 |
| Yang, MK | 1 |
| Lim, JH | 1 |
| Seo, HW | 1 |
| Yi, KY | 1 |
| Yoo, SE | 1 |
| Lee, BH | 1 |
| Won, HS | 1 |
| Lee, CS | 1 |
| Choi, WS | 1 |
| Shin, HS | 1 |
| Ji, Y | 1 |
| Pang, QF | 1 |
| Xu, G | 1 |
| Wang, L | 2 |
| Wang, JK | 1 |
| Zeng, YM | 1 |
| Moritani, K | 1 |
| Miyazaki, T | 1 |
| Miyoshi, S | 1 |
| Asanagi, M | 1 |
| Zhao, LS | 1 |
| Mitamura, H | 1 |
| Ogawa, S | 1 |
| Yao, Z | 2 |
| Hide, EJ | 2 |
| Ney, P | 1 |
| Piper, J | 2 |
| Vane, JR | 1 |
| Sargent, CA | 1 |
| Wilde, MW | 1 |
| Dzwonczyk, S | 2 |
| Tuttle, JG | 1 |
| Murray, HN | 1 |
| Atwal, K | 1 |
| Grover, GJ | 2 |
| Elliott, GT | 1 |
| Mei, DA | 1 |
| Kita, H | 1 |
| Miura, T | 2 |
| Tsuchida, A | 2 |
| Hasegawa, T | 1 |
| Shimamoto, K | 2 |
| Tracey, WR | 1 |
| Magee, W | 1 |
| Masamune, H | 1 |
| Oleynek, JJ | 1 |
| Hill, RJ | 1 |
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| Fryer, RM | 1 |
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| Sleph, PG | 1 |
99 other studies available for 5-hydroxydecanoate and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
[Protective effect of uridine on metabolic processes in rat myocardum during its ischemia/reperfusion damage].
Topics: Adenosine Triphosphate; Animals; Antioxidants; Decanoic Acids; Glutathione; Hydroxy Acids; Lipid Per | 2019 |
Cardioprotective effect of anisodamine against ischemia/reperfusion injury through the mitochondrial ATP-sensitive potassium channel.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Decanoic Acids; Energy Me | 2021 |
Ischemic postconditioning prevents surge of presynaptic glutamate release by activating mitochondrial ATP-dependent potassium channels in the mouse hippocampus.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; | 2019 |
[Cyclosporin A-sensitive mitochondrial pore as a target of cardioprotective action of hydrogen sulfide donor].
Topics: Animals; Calcium; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Heart; Hydrogen Sulfide; Hydroxy | 2013 |
9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Biomarkers; Cardiotonic Agents; Decanoic Acids; Enzyme Inhibitors; | 2013 |
Role of mitochondrial permeability transition pore and mitochondrial ATP-sensitive potassium channels in the protective effects of ischemic preconditioning in isolated hearts from fed and fasted rats.
Topics: Animals; Cardiotonic Agents; Decanoic Acids; Deoxyglucose; Diazoxide; Fasting; Female; Hydroxy Acids | 2014 |
Anti-arrhythmic effect of diosgenin in reperfusion-induced myocardial injury in a rat model: activation of nitric oxide system and mitochondrial KATP channel.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Decanoic Acids; Diosgenin | 2014 |
Dodecafluoropentane emulsion elicits cardiac protection against myocardial infarction through an ATP-Sensitive K+ channel dependent mechanism.
Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Decanoic Acids; Fluorocarbons; Heart; Hydroxy Aci | 2014 |
Role of mitochondrial ATP-sensitive potassium channel-mediated PKC-ε in delayed protection against myocardial ischemia/reperfusion injury in isolated hearts of sevoflurane-preconditioned rats.
Topics: Animals; Anti-Arrhythmia Agents; Blotting, Western; Caspase 8; Decanoic Acids; Heart; Hemodynamics; | 2015 |
K(ATP) channels and MPTP are involved in the cardioprotection bestowed by chronic intermittent hypobaric hypoxia in the developing rat.
Topics: Animals; Atmospheric Pressure; Atractyloside; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Diaz | 2015 |
Stimulation of Oxytocin Receptor during Early Reperfusion Period Protects the Heart against Ischemia/Reperfusion Injury: the Role of Mitochondrial ATP-Sensitive Potassium Channel, Nitric Oxide, and Prostaglandins.
Topics: Animals; Decanoic Acids; Hydroxy Acids; KATP Channels; Male; Myocardial Reperfusion Injury; Nitric O | 2015 |
Myocardial triggers involved in activation of remote ischaemic preconditioning.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Heart; Hindlimb; Hydrogen Peroxide; Hydroxy Acids; | 2016 |
The cardioprotective effect of naringenin against ischemia-reperfusion injury through activation of ATP-sensitive potassium channel in rat.
Topics: Animals; Cardiotonic Agents; Decanoic Acids; Flavanones; Glyburide; Heart; Hydroxy Acids; KATP Chann | 2016 |
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Stero | 2009 |
Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Decanoic Acids; Dogs; Femal | 2008 |
[Cardioprotective effects of flokalin: relative role of activation of sarcolemmal and mitochondrial adenosine triphosphate-dependent potassium channels].
Topics: Animals; Cardiotonic Agents; Decanoic Acids; Guinea Pigs; Hydroxy Acids; In Vitro Techniques; Male; | 2008 |
The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels.
Topics: Animals; Anti-Arrhythmia Agents; Cytoprotection; Decanoic Acids; Electron Transport Complex II; Hydr | 2009 |
Activation of peripheral delta2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nervous System; Benzophenanthridine | 2009 |
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Topics: Androstadienes; Anilides; Animals; Blood Glucose; Blotting, Western; Decanoic Acids; Disease Models, | 2009 |
The ceiling effect of pharmacological postconditioning with the phytoestrogen genistein is reversed by the GSK3beta inhibitor SB 216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione] through mitochondrial ATP-dependent potassium c
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Decanoic Acids; Estradiol; Genistein; Glycogen Synt | 2009 |
Mitochondrial KATP channel inhibition blunts arrhythmia protection in ischemic exercised hearts.
Topics: Animals; Arrhythmias, Cardiac; Benzamides; Catalase; Decanoic Acids; Disease Models, Animal; Electro | 2010 |
Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation.
Topics: Animals; Cacao; Catechin; Decanoic Acids; Dose-Response Relationship, Drug; Hydroxy Acids; Male; Mic | 2010 |
Noninvasive delayed limb ischemic preconditioning attenuates myocardial ischemia-reperfusion injury in rats by a mitochondrial K(ATP) channel-dependent mechanism.
Topics: Animals; Arrhythmias, Cardiac; Decanoic Acids; Glutathione Peroxidase; Hydroxy Acids; Ischemic Preco | 2011 |
[The protective role and the mechanisms of puerarin on isolated rat heart during ischemia/reperfusion].
Topics: Animals; Decanoic Acids; Hydroxy Acids; Isoflavones; Male; Mitochondria, Heart; Mitochondrial Membra | 2006 |
Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.
Topics: Animals; Benzophenanthridines; Benzylidene Compounds; Decanoic Acids; Glyburide; Hydroxy Acids; Isch | 2010 |
Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.
Topics: Animals; Calcium; Cardiotonic Agents; Decanoic Acids; Diazoxide; Disease Models, Animal; Guanidines; | 2011 |
ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat.
Topics: Animals; Atractyloside; Biflavonoids; Cardiotonic Agents; Catechin; Decanoic Acids; Glyburide; Heart | 2011 |
Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes.
Topics: Aged; Anesthetics, Inhalation; Blotting, Western; Decanoic Acids; Desflurane; Diabetes Mellitus, Typ | 2011 |
Hypercholesterolemia abrogates sevoflurane-induced delayed preconditioning against myocardial infarct in rats by alteration of nitric oxide synthase signaling.
Topics: Amidines; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; bcl-Associated Death Protein; Be | 2012 |
High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Glucose; Decanoic Acids; Diazoxide; Do | 2012 |
Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart?
Topics: Anesthesia; Animals; Decanoic Acids; Electrocardiography; Energy Metabolism; Enzyme Inhibitors; Hear | 2012 |
H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.
Topics: Animals; Apoptosis; Cardiotonic Agents; Decanoic Acids; Dogs; Hydrogen; Hydroxy Acids; In Situ Nick- | 2012 |
Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis.
Topics: Animals; Anti-Arrhythmia Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Deca | 2012 |
Acute and chronic cardioprotection by the enkephalin analogue, Eribis peptide 94, is mediated via activation of nitric oxide synthase and adenosine triphosphate-regulated potassium channels.
Topics: Animals; Benzamides; Cardiotonic Agents; Decanoic Acids; Enkephalins; Hydroxy Acids; KATP Channels; | 2012 |
Pretreatment with xenon protected immature rabbit heart from ischaemia/reperfusion injury by opening of the mitoKATP channel.
Topics: Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Decanoic Acids; Hydroxy Acids; Male; Mitoc | 2013 |
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?
Topics: Adenosine; Analysis of Variance; Animals; Atractyloside; Calcineurin Inhibitors; Cyclosporine; Decan | 2002 |
Cardioprotection by multiple preconditioning cycles does not require mitochondrial K(ATP) channels in pigs.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiotonic Agents; Decanoi | 2002 |
The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Decanoic Acids; Diaz | 2002 |
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Aging; Alkaloids; Animals; Arrhythmias, Cardiac; Benzo | 2003 |
Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Blood Pressure; Decanoic Acids; | 2003 |
Mitochondrial K ATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac | 2003 |
Quinaprilat reduces myocardial infarct size involving nitric oxide production and mitochondrial KATP channel in rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Decanoic Acids; Heart Ven | 2003 |
Ischaemic preconditioning and a mitochondrial KATP channel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; | 2003 |
Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury.
Topics: Alkenes; Animals; Cattle; Decanoic Acids; Echocardiography; Heart; Hemodynamics; Humans; Hydroxy Aci | 2004 |
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Ion Channel Gating; Ische | 2004 |
Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Decanoic Acids; Disease Models, Animal; Glyburide; He | 2004 |
Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning.
Topics: Animals; ATP-Binding Cassette Transporters; Benzimidazoles; Cell Survival; Coronary Circulation; Dec | 2005 |
mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Chick Embryo; Chickens; Decanoic Acids; Diaz | 2005 |
Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.
Topics: Acetophenones; Angiotensin II; Animals; Cardiotonic Agents; Decanoic Acids; Enzyme Activation; Enzym | 2005 |
Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model?
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; ATP-Binding Cassett | 2005 |
Overexpression of heat-shock protein 20 in rat heart myogenic cells confers protection against simulated ischemia/reperfusion injury.
Topics: Adenoviridae; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Decanoic Acids; HSP20 Heat-S | 2005 |
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat.
Topics: Animals; ATP-Binding Cassette Transporters; Benzamides; Calcium; Decanoic Acids; Female; Heart; Hydr | 2005 |
Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms.
Topics: Alkaloids; Animals; Benzophenanthridines; Bradykinin; Coronary Circulation; Decanoic Acids; Hydroxy | 2005 |
Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiac Output; Decanoic Acids; Glyburide; | 2006 |
Isoflurane and sevoflurane during reperfusion prevent recovery from ischaemia in mitochondrial KATP channel blocker pretreated hearts.
Topics: Anesthetics, Inhalation; Animals; Decanoic Acids; Hemodynamics; Hydroxy Acids; Ischemic Precondition | 2006 |
Early pharmacological preconditioning by erythropoietin mediated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart.
Topics: Amidines; Animals; Benzylamines; Decanoic Acids; Enzyme Inhibitors; Erythropoietin; Heart; Hydroxy A | 2006 |
Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart.
Topics: Animals; Atractyloside; Cardiotonic Agents; Decanoic Acids; Heart; Hydroxy Acids; In Vitro Technique | 2006 |
Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischemia-reperfusion model in isolated rat hearts.
Topics: Animals; Arrhythmias, Cardiac; Benzamides; Coronary Circulation; Decanoic Acids; Dose-Response Relat | 2006 |
The role of ATP sensitive K+ channels and of nitric oxide synthase on myocardial ischemia/reperfusion-induced apoptosis.
Topics: Animals; Apoptosis; Benzamides; Decanoic Acids; Hydroxy Acids; Immunoenzyme Techniques; In Situ Nick | 2006 |
Blocking cardiac ATP-sensitive K+ channels reduces hydroxyl radicals caused by potassium chloride-induced depolarization in the rat myocardium.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Glyburide; Hydroxy Acids; Hydroxybenzoates; Hydroxy | 2006 |
The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Topics: Alkynes; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Decanoic Acids; Endotoxins; Enzyme | 2006 |
Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Cell Hypoxia; Cell Shape; Cells, Cultured; | 2006 |
Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance.
Topics: Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Immunoblotting; In Vitro Techniques; Insulin Resi | 2007 |
The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic Acids; Disease Models, Animal; Diterpe | 2007 |
Cardioprotective effects of stretch are mediated by activation of sarcolemmal, not mitochondrial, ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cell Shape; Cell Survival; Decanoic Acids; Energy Metab | 2007 |
Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against ischemia-reperfusion in the rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Ulcer Agents; Cell Respiration; Cells, Cultured; Creatine Kina | 2007 |
Anesthetic preconditioning confers acute cardioprotection via up-regulation of manganese superoxide dismutase and preservation of mitochondrial respiratory enzyme activity.
Topics: Adenosine Triphosphate; Anesthetics; Animals; Decanoic Acids; Hydroxy Acids; Ischemic Preconditionin | 2008 |
Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes.
Topics: Animals; Calcium; Cell Size; Cell Survival; Cells, Cultured; Decanoic Acids; Heart Ventricles; Hydro | 2008 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Anima | 2008 |
[Effect of postconditioning on rat hearts suffered from long-term hypothermic preservation].
Topics: Animals; Cryopreservation; Decanoic Acids; Heart; Hydroxy Acids; In Vitro Techniques; Ischemic Preco | 2007 |
Preconditioning by isoflurane retains its protection against ischemia-reperfusion injury in postinfarct remodeled rat hearts.
Topics: Anesthetics, Inhalation; Animals; Cardiotonic Agents; Chromones; Coronary Vessels; Decanoic Acids; D | 2008 |
Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Benzophenanthridines; Blotting, Western; Cardiotonic Agents; Decan | 2008 |
Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species.
Topics: Acetylcysteine; Animals; Anti-Arrhythmia Agents; Antioxidants; Decanoic Acids; Diazoxide; Hydroxy Ac | 2009 |
Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers.
Topics: Animals; Cardiotonic Agents; Decanoic Acids; Diazoxide; Dicarbethoxydihydrocollidine; Fiber Optic Te | 2008 |
KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.
Topics: Animals; Aorta; Benzopyrans; Cardiotonic Agents; Decanoic Acids; Disease Models, Animal; Dose-Respon | 2008 |
Exogenous hydrogen sulfide postconditioning protects isolated rat hearts against ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Buffers; Coronary Circulation; Creatine Kinase; Decanoic Acids; Dose-Respon | 2008 |
Blockade of ATP-sensitive potassium channels by 5-hydroxydecanoate suppresses monophasic action potential shortening during regional myocardial ischemia.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bl | 1994 |
The ATP-dependent potassium channel: an endogenous cardioprotective mechanism.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Coronary Disease; Decanoic Acids; Disease | 1994 |
Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Arrhythmia Agents; Biotransformation; Blood Press | 1995 |
Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arterial Occlusive Diseases; Blood Pressure | 1995 |
Glyburide-reversible cardioprotective effects of calcium-independent phospholipase A2 inhibition in ischemic rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Coronary Circulation; Decanoic Acids; Dose-Response Relati | 1996 |
Monophosphoryl lipid A attenuates myocardial stunning in dogs: role of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Gas Analysis; Blood Pressure; Coronary Circulation; Decanoic | 1998 |
Suppression of reperfusion arrhythmias by preconditioning is inhibited by an ATP-sensitive potassium channel blocker, 5-hydroxydecanoate, but not by protein kinase C blockers in the rat.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Decanoic Acids; Hemod | 1998 |
Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation.
Topics: Adenosine; Adenylyl Cyclases; Animals; Anti-Arrhythmia Agents; Binding, Competitive; CHO Cells; Colf | 1998 |
JTV-519, a novel cardioprotective agent, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles.
Topics: Action Potentials; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel | 2000 |
Opioid-induced cardioprotection against myocardial infarction and arrhythmias: mitochondrial versus sarcolemmal ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; B | 2000 |
Cardioprotection by K(ATP) channels in wild-type hearts and hearts overexpressing A(1)-adenosine receptors.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Heart; Hydroxy Acids; In Vitro Techniques; Mice; Mi | 2000 |
Chronic ethanol-induced myocardial protection requires activation of mitochondrial K(ATP) channels.
Topics: Alcohol Drinking; Animals; Coronary Circulation; Creatine Kinase; Decanoic Acids; Ethanol; Hydroxy A | 2000 |
Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Collateral Circulation; Coronary Circulat | 2001 |
Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: role of K(ATP) channels.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Decanoic Acids; Diazoxide; Hydroxy Acids; Ion Channel Gati | 2001 |
Signal transduction of opioid-induced cardioprotection in ischemia-reperfusion.
Topics: Animals; ATP-Binding Cassette Transporters; Benzamides; Benzylidene Compounds; Cell Survival; Chick | 2001 |
Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Decanoic Acids; Diazoxide; Glyburide; Hydroxy | 2001 |
Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; | 2002 |
Delayed preconditioning induced by lipoteichoic acid from B. subtilis and S. aureus is not blocked by administration of 5-hydroxydecanoate.
Topics: Animals; Bacillus subtilis; Decanoic Acids; Hemodynamics; Hydroxy Acids; Ischemic Preconditioning, M | 2002 |
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice.
Topics: Animals; Benzamides; Decanoic Acids; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, M | 2002 |
Selective mitochondrial K(ATP) channel activation results in antiarrhythmic effect during experimental myocardial ischemia/reperfusion in anesthetized rabbits.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressur | 2002 |
Differential effects of sarcolemmal and mitochondrial K(ATP) channels activated by 17 beta-estradiol on reperfusion arrhythmias and infarct sizes in canine hearts.
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Benzamides; Blood Pressure; Decanoic Acids; Dogs; Elec | 2002 |
The role of mitochondrial and sarcolemmal K(ATP) channels in canine ethanol-induced preconditioning in vivo.
Topics: Adenosine Triphosphate; Animals; Benzamides; Coronary Circulation; Decanoic Acids; Dogs; Ethanol; He | 2002 |
Reduction of ischemic damage in isolated rat hearts by the potassium channel opener, RP 52891.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Decanoic Acids; Glyburide; Heart; Hydroxy Acids; | 1990 |