5-hydroxydecanoate has been researched along with Cerebral Ischemia in 8 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested whether Diaz preserves endothelium-dependent (hypercapnia) or -independent [iloprost (Ilo)] cerebrovascular dilator responses after ischemia-reperfusion (I/R) in newborn pigs and whether the effect of Diaz is sensitive to 5-hydroxydecanoate (5-HD), an inhibitor of mitoKATP channels." | 7.73 | Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets. ( Bari, F; Busija, DW; Domoki, F; Farkas, E; Kis, B; Nagy, K, 2005) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 5.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "The number of FJ-positive degenerating neurons in the CA1 area of the hippocampus, the cerebellum and the thalamic reticular nucleus of the ketogenic diet-fed rats with or without glibenclamide or 5-hydroxydecanoate pre-treatment before cardiac arrest-induced cerebral ischemia is zero." | 3.75 | Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration. ( Pham, L; Tai, KK; Truong, DD, 2009) |
| " We tested whether Diaz preserves endothelium-dependent (hypercapnia) or -independent [iloprost (Ilo)] cerebrovascular dilator responses after ischemia-reperfusion (I/R) in newborn pigs and whether the effect of Diaz is sensitive to 5-hydroxydecanoate (5-HD), an inhibitor of mitoKATP channels." | 3.73 | Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets. ( Bari, F; Busija, DW; Domoki, F; Farkas, E; Kis, B; Nagy, K, 2005) |
| "Obesity is associated with increased infarct volumes and adverse outcomes following ischemic stroke." | 1.40 | Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels. ( Chen, Y; Fang, X; Jiang, Y; Xu, J; Yang, Z; Zhang, Y, 2014) |
| "Pretreatment with diazoxide protected both Sur1KO and wild-type neurons, while 5-hydroxydecanoate augmented neurodegeneration in both strains of animals when administered before a 20-minute bout of ischemia." | 1.32 | Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels. ( Aguilar-Bryan, L; Barrios, R; Bryan, J; Goodman, JC; Muñoz, A; Nakazaki, M; Onetti, CG, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Z | 1 |
| Chen, Y | 1 |
| Zhang, Y | 1 |
| Jiang, Y | 1 |
| Fang, X | 1 |
| Xu, J | 1 |
| Watanabe, M | 1 |
| Katsura, K | 1 |
| Ohsawa, I | 1 |
| Mizukoshi, G | 1 |
| Takahashi, K | 1 |
| Asoh, S | 1 |
| Ohta, S | 1 |
| Katayama, Y | 1 |
| Tai, KK | 1 |
| Pham, L | 1 |
| Truong, DD | 1 |
| Robin, E | 1 |
| Simerabet, M | 1 |
| Hassoun, SM | 1 |
| Adamczyk, S | 1 |
| Tavernier, B | 1 |
| Vallet, B | 1 |
| Bordet, R | 1 |
| Lebuffe, G | 1 |
| Muñoz, A | 1 |
| Nakazaki, M | 1 |
| Goodman, JC | 1 |
| Barrios, R | 1 |
| Onetti, CG | 1 |
| Bryan, J | 1 |
| Aguilar-Bryan, L | 1 |
| Liu, D | 1 |
| Slevin, JR | 1 |
| Lu, C | 1 |
| Chan, SL | 1 |
| Hansson, M | 1 |
| Elmér, E | 1 |
| Mattson, MP | 1 |
| Domoki, F | 2 |
| Kis, B | 1 |
| Nagy, K | 1 |
| Farkas, E | 1 |
| Busija, DW | 2 |
| Bari, F | 2 |
| Perciaccante, JV | 1 |
| Veltkamp, R | 1 |
8 other studies available for 5-hydroxydecanoate and Cerebral Ischemia
| Article | Year |
|---|---|
Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: role of brain mitochondrial KATP channels.
Topics: Animals; Body Weight; Brain; Brain Injuries; Brain Ischemia; Decanoic Acids; Diazoxide; Diet, High-F | 2014 |
Involvement of mitoKATP channel in protective mechanisms of cerebral ischemic tolerance.
Topics: Animals; Anti-Arrhythmia Agents; Brain Ischemia; Cells, Cultured; Decanoic Acids; Diazoxide; Gerbill | 2008 |
Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.
Topics: Animals; Brain Ischemia; Decanoic Acids; Diet, Ketogenic; Fluoresceins; Glyburide; Heart Arrest; Hyd | 2009 |
Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel.
Topics: Animals; Behavior, Animal; Brain Ischemia; Calcium; Decanoic Acids; Hydroxy Acids; Infarction, Middl | 2011 |
Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cell Survival; Decanoic Acids; Diazoxide; Hippocamp | 2003 |
Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Death; Cell Hypoxia; Cells, Cultured; Cyanides; Decanoic Ac | 2003 |
Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Blood Pressure; Brain Ischemia; Cells, Cultured; Cerebrovascu | 2005 |
Mitochondrial potassium channel opener diazoxide preserves neuronal-vascular function after cerebral ischemia in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Brain Ischemia; Decanoic Acids; Diazoxide; Dose-Response Rela | 1999 |