5-hydroxydecanoate has been researched along with Cerebral Infarction, Middle Cerebral Artery in 6 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sevoflurane treatment also caused increased phosphorylation of p38 MAPK at 24 and 72 h after reperfusion." | 1.38 | Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation. ( Guo, Q; Wang, E; Wang, N; Xia, P; Ye, Z; Yuan, Y, 2012) |
| "Rats were exposed to 90 minutes of middle cerebral artery occlusion followed by 72 hours of reperfusion." | 1.38 | Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury. ( Deng, J; Dong, H; Li, Y; Li, Z; Luan, Q; Sun, J; Tong, L; Xiong, L, 2012) |
| "Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, E | 1 |
| Fujiki, M | 1 |
| Nagai, Y | 1 |
| Shiqi, K | 1 |
| Kubo, T | 1 |
| Ishii, K | 1 |
| Abe, T | 1 |
| Kobayashi, H | 1 |
| Robin, E | 1 |
| Simerabet, M | 1 |
| Hassoun, SM | 1 |
| Adamczyk, S | 1 |
| Tavernier, B | 1 |
| Vallet, B | 1 |
| Bordet, R | 1 |
| Lebuffe, G | 1 |
| Ye, Z | 1 |
| Guo, Q | 1 |
| Wang, N | 1 |
| Xia, P | 1 |
| Yuan, Y | 1 |
| Wang, E | 1 |
| Sun, J | 1 |
| Tong, L | 1 |
| Luan, Q | 1 |
| Deng, J | 1 |
| Li, Y | 1 |
| Li, Z | 1 |
| Dong, H | 1 |
| Xiong, L | 1 |
| Horiguchi, T | 1 |
| Kis, B | 1 |
| Rajapakse, N | 1 |
| Shimizu, K | 1 |
| Busija, DW | 1 |
| Lee, JJ | 1 |
| Li, L | 1 |
| Jung, HH | 1 |
| Zuo, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for 5-hydroxydecanoate and Cerebral Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.
Topics: Androstadienes; Animals; Brain; Brain Infarction; Central Nervous System Agents; Decanoic Acids; Dia | 2010 |
Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel.
Topics: Animals; Behavior, Animal; Brain Ischemia; Calcium; Decanoic Acids; Hydroxy Acids; Infarction, Middl | 2011 |
Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Infarction; Cell Count; Decanoic Acids; | 2012 |
Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury.
Topics: Animals; Anti-Arrhythmia Agents; Apoptosis; Brain Diseases; Decanoic Acids; Hydroxy Acids; Infarctio | 2012 |
Opening of mitochondrial ATP-sensitive potassium channels is a trigger of 3-nitropropionic acid-induced tolerance to transient focal cerebral ischemia in rats.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cerebral Cortex; Decanoic Acids; Glyburide; Hydrox | 2003 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |