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5-hydroxydecanoate and Cardiomegaly

5-hydroxydecanoate has been researched along with Cardiomegaly in 3 studies

5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Cardiac hypertrophy has been demonstrated to decreases the ATP-sensitive potassium channels (K(ATP)), the major protective mechanism following the energy depletion, a common condition seen during the reperfusion after open heart surgery."1.32Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels. ( Maeda, H; Rajesh, KG; Sasaguri, S; Suzuki, R; Xing, Y, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rajesh, KG1
Sasaguri, S1
Suzuki, R1
Xing, Y1
Maeda, H1
Xia, Y2
Rajapurohitam, V1
Cook, MA2
Karmazyn, M2
Javadov, S1
Gan, TX1
Pang, T1

Other Studies

3 other studies available for 5-hydroxydecanoate and Cardiomegaly

ArticleYear
Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels.
    International journal of cardiology, 2004, Volume: 96, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Decanoic Acids; Disease Models, Animal; Glyburide; He

2004
Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide.
    Journal of molecular and cellular cardiology, 2004, Volume: 37, Issue:5

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cardiomegal

2004
Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Animals, Newborn; Calcium; Cardiomegaly; Cells, Cultured; Decanoic Acids; Diazoxide; Hydrox

2007