5-hydroxydecanoate has been researched along with Cardiomegaly in 3 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac hypertrophy has been demonstrated to decreases the ATP-sensitive potassium channels (K(ATP)), the major protective mechanism following the energy depletion, a common condition seen during the reperfusion after open heart surgery." | 1.32 | Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels. ( Maeda, H; Rajesh, KG; Sasaguri, S; Suzuki, R; Xing, Y, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rajesh, KG | 1 |
| Sasaguri, S | 1 |
| Suzuki, R | 1 |
| Xing, Y | 1 |
| Maeda, H | 1 |
| Xia, Y | 2 |
| Rajapurohitam, V | 1 |
| Cook, MA | 2 |
| Karmazyn, M | 2 |
| Javadov, S | 1 |
| Gan, TX | 1 |
| Pang, T | 1 |
3 other studies available for 5-hydroxydecanoate and Cardiomegaly
| Article | Year |
|---|---|
Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Decanoic Acids; Disease Models, Animal; Glyburide; He | 2004 |
Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cardiomegal | 2004 |
Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Calcium; Cardiomegaly; Cells, Cultured; Decanoic Acids; Diazoxide; Hydrox | 2007 |