5-hydroxydecanoate has been researched along with Brain Infarction in 4 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with diazoxide significantly reduced infarct volume and brain edema formation after ASDH." | 1.39 | The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma. ( Nakagawa, I; Nakase, H; Nishimura, F; Park, YS; Tamura, K; Wajima, D, 2013) |
| "Sevoflurane treatment also caused increased phosphorylation of p38 MAPK at 24 and 72 h after reperfusion." | 1.38 | Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation. ( Guo, Q; Wang, E; Wang, N; Xia, P; Ye, Z; Yuan, Y, 2012) |
| "Pretreatment with diazoxide significantly reduced the infarct volume from 6." | 1.33 | MitoKATP-channel opener protects against neuronal death in rat venous ischemia. ( Alessandri, B; Heimann, A; Kempski, O; Nakagawa, I, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, E | 1 |
| Fujiki, M | 1 |
| Nagai, Y | 1 |
| Shiqi, K | 1 |
| Kubo, T | 1 |
| Ishii, K | 1 |
| Abe, T | 1 |
| Kobayashi, H | 1 |
| Ye, Z | 1 |
| Guo, Q | 1 |
| Wang, N | 1 |
| Xia, P | 1 |
| Yuan, Y | 1 |
| Wang, E | 1 |
| Nakagawa, I | 2 |
| Wajima, D | 1 |
| Tamura, K | 1 |
| Nishimura, F | 1 |
| Park, YS | 1 |
| Nakase, H | 1 |
| Alessandri, B | 1 |
| Heimann, A | 1 |
| Kempski, O | 1 |
4 other studies available for 5-hydroxydecanoate and Brain Infarction
| Article | Year |
|---|---|
The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.
Topics: Androstadienes; Animals; Brain; Brain Infarction; Central Nervous System Agents; Decanoic Acids; Dia | 2010 |
Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Infarction; Cell Count; Decanoic Acids; | 2012 |
The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma.
Topics: Animals; Brain Infarction; Decanoic Acids; Diazoxide; Disease Models, Animal; Hematoma, Subdural, Ac | 2013 |
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Infarction; Cell Death; Ce | 2005 |