5-hydroxydecanoate has been researched along with Anoxemia in 29 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| " To elucidate whether and how the mitoKATP channel protects against hypoxia-reoxygenation (H-R)-induced mitochondrial dysfunction in fish, we first determined the mitochondrial bioenergetic effects of two key modulators of the channel, diazoxide and 5-hydroxydecanoate (5-HD), using a wide range of doses." | 3.83 | Bioenergetic and volume regulatory effects of mitoKATP channel modulators protect against hypoxia-reoxygenation-induced mitochondrial dysfunction. ( Kamunde, C; Onukwufor, JO; Stevens, D, 2016) |
| " Seven minutes before hypoxia reoxygenation, muscles were exposed to 4 min of hypoxia and 7 min of reoxygenation or 15 min of sevoflurane at concentrations of 1, 2, and 3%." | 3.72 | Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro. ( Babatasi, G; Bricard, H; Ducouret, P; Gérard, JL; Haelewyn, B; Hanouz, JL; Khayat, A; Massetti, M; Terrien, X; Yvon, A, 2003) |
| "We characterized an anoxia/reoxygenation (A/R) model using freshly isolated adult rat cardiomyocytes." | 1.42 | Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis. ( Cao, S; Liu, X; Liu, Y; Sun, W; Yu, T; Zhang, L; Zhao, L, 2015) |
| "Desflurane (6%) was administered during the first 5 min of reoxygenation either alone or in the presence of calphostin C (PKC inhibitor) or 5-hydroxydecanoate (5-HD) (mitoK(ATP) channel antagonist)." | 1.37 | Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes. ( Buléon, C; Galera, P; Gérard, JL; Hanouz, JL; Lemoine, S; Massetti, M; Zhu, L, 2011) |
| "During anoxia, [Ca(2+)](c) increased 9." | 1.35 | Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle. ( Buck, LT; Cooray, M; Pamenter, ME; Shin, DS, 2008) |
| "Pretreatment with diazoxide protected both Sur1KO and wild-type neurons, while 5-hydroxydecanoate augmented neurodegeneration in both strains of animals when administered before a 20-minute bout of ischemia." | 1.32 | Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels. ( Aguilar-Bryan, L; Barrios, R; Bryan, J; Goodman, JC; Muñoz, A; Nakazaki, M; Onetti, CG, 2003) |
| "We evaluated responses to anoxia-reoxygenation in wild-type (WT) and transgenic (Trans) hearts with approximately 200-fold overexpression of A1ARs." | 1.31 | A1 adenosine receptor overexpression decreases stunning from anoxia-reoxygenation: role of the mitochondrial K(ATP) channel. ( Byford, AM; Cerniway, RJ; Headrick, JP; Lankford, AR; Matherne, GP; Morrison, RR; Van Wylen, DG, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 16 (55.17) | 29.6817 |
| 2010's | 10 (34.48) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Maslov, LN | 2 |
| Sementsov, AS | 1 |
| Naryzhnaya, NV | 1 |
| Derkachev, IA | 1 |
| Fu, F | 1 |
| Gusakova, SV | 1 |
| Sarybaev, A | 1 |
| Mironova, GD | 2 |
| Rozova, EV | 2 |
| Belosludtseva, NV | 2 |
| Man'kovskaya, IN | 1 |
| Mankovskaya, IN | 1 |
| Khmil, NV | 1 |
| Levin, SG | 1 |
| Shamsutdinova, AA | 1 |
| Godukhin, OV | 1 |
| Dong, L | 1 |
| Li, Y | 2 |
| Hu, H | 1 |
| Shi, L | 1 |
| Chen, J | 1 |
| Wang, B | 1 |
| Chen, C | 2 |
| Zhu, H | 1 |
| Li, Q | 2 |
| Zhang, L | 2 |
| Bu, HM | 1 |
| Yang, CY | 1 |
| Wang, ML | 1 |
| Ma, HJ | 1 |
| Sun, H | 1 |
| Zhang, Y | 1 |
| Cao, S | 1 |
| Liu, Y | 1 |
| Sun, W | 1 |
| Zhao, L | 1 |
| Liu, X | 1 |
| Yu, T | 1 |
| Onukwufor, JO | 1 |
| Stevens, D | 1 |
| Kamunde, C | 1 |
| Abdallah, Y | 1 |
| Wolf, C | 1 |
| Meuter, K | 1 |
| Piper, HM | 1 |
| Reusch, HP | 1 |
| Ladilov, Y | 1 |
| Paddenberg, R | 1 |
| Faulhammer, P | 1 |
| Goldenberg, A | 1 |
| Gries, B | 1 |
| Heinl, J | 1 |
| Kummer, W | 1 |
| Naryzhnaia, NV | 1 |
| Neckar, J | 2 |
| Lishmanov, IuB | 1 |
| Kolar, F | 3 |
| Lasukova, TV | 1 |
| Lemoine, S | 1 |
| Zhu, L | 1 |
| Buléon, C | 1 |
| Massetti, M | 2 |
| Gérard, JL | 2 |
| Galera, P | 1 |
| Hanouz, JL | 2 |
| Shu, Y | 1 |
| Li, YL | 1 |
| Zhang, LP | 1 |
| Chen, CS | 1 |
| Szárszoi, O | 1 |
| Koten, L | 1 |
| Papousek, F | 1 |
| Ost'ádal, B | 1 |
| Grover, GJ | 1 |
| Ostádalová, I | 1 |
| Ostádal, B | 1 |
| Jarkovská, D | 1 |
| Muñoz, A | 1 |
| Nakazaki, M | 1 |
| Goodman, JC | 1 |
| Barrios, R | 1 |
| Onetti, CG | 1 |
| Bryan, J | 1 |
| Aguilar-Bryan, L | 1 |
| MacCormack, TJ | 2 |
| Treberg, JR | 1 |
| Almeida-Val, VM | 1 |
| Val, AL | 1 |
| Driedzic, WR | 2 |
| Yvon, A | 1 |
| Haelewyn, B | 1 |
| Terrien, X | 1 |
| Babatasi, G | 1 |
| Khayat, A | 1 |
| Ducouret, P | 1 |
| Bricard, H | 1 |
| Zhu, HF | 1 |
| Dong, JW | 1 |
| Zhu, WZ | 1 |
| Ding, HL | 1 |
| Zhou, ZN | 1 |
| Sarre, A | 1 |
| Lange, N | 1 |
| Kucera, P | 1 |
| Raddatz, E | 1 |
| Colantuono, G | 1 |
| Tiravanti, EA | 1 |
| Di Venosa, N | 1 |
| Cazzato, A | 1 |
| Rastaldo, R | 1 |
| Cagiano, R | 1 |
| D'Agostino, D | 1 |
| Federici, A | 1 |
| Fiore, T | 1 |
| Pamenter, ME | 1 |
| Shin, DS | 1 |
| Cooray, M | 1 |
| Buck, LT | 1 |
| Baker, JE | 3 |
| Holman, P | 1 |
| Gross, GJ | 3 |
| Tanonaka, K | 1 |
| Taguchi, T | 1 |
| Koshimizu, M | 1 |
| Ando, T | 1 |
| Morinaka, T | 1 |
| Yogo, T | 1 |
| Konishi, F | 1 |
| Takeo, S | 1 |
| Eells, JT | 1 |
| Henry, MM | 1 |
| Kong, X | 1 |
| Tweddell, JS | 1 |
| Korge, P | 1 |
| Honda, HM | 1 |
| Weiss, JN | 1 |
| Cerniway, RJ | 1 |
| Morrison, RR | 1 |
| Byford, AM | 1 |
| Lankford, AR | 1 |
| Headrick, JP | 1 |
| Van Wylen, DG | 1 |
| Matherne, GP | 1 |
29 other studies available for 5-hydroxydecanoate and Anoxemia
| Article | Year |
|---|---|
The Role of Mitochondrial K
Topics: Adenosine Triphosphate; Animals; Glyburide; Hypoxia; KATP Channels; Male; Myocardial Infarction; Rat | 2022 |
Dynamic Restructuring of the Myocardial Mitochondria in Response to Uridine Modulation of the Activity of Mitochondrial ATP-Dependent Potassium Channel under Conditions of Acute Hypoxic Hypoxia.
Topics: Animals; Cell Hypoxia; Decanoic Acids; Hydroxy Acids; Hypoxia; Male; Mitochondria, Heart; Myocardium | 2019 |
Uridine as a protector against hypoxia-induced lung injury.
Topics: Animals; Decanoic Acids; Hydroxy Acids; Hypoxia; Lung Injury; Male; Microscopy, Electron; Mitochondr | 2019 |
Comparison of effects of ATP-gated potassium channel blockers on activity variations of rat CA1 pyramidal neurons in hippocampal slices triggered by short-term hypoxia.
Topics: Animals; Decanoic Acids; Glyburide; Hippocampus; Hydroxy Acids; Hypoxia; Male; Potassium Channel Blo | 2013 |
Potential therapeutic targets for hypoxia-induced pulmonary artery hypertension.
Topics: Animals; Blood Pressure; Cell Proliferation; Chemokine CCL2; Decanoic Acids; Hydroxy Acids; Hyperten | 2014 |
K(ATP) channels and MPTP are involved in the cardioprotection bestowed by chronic intermittent hypobaric hypoxia in the developing rat.
Topics: Animals; Atmospheric Pressure; Atractyloside; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Diaz | 2015 |
Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis.
Topics: Acyl-CoA Dehydrogenase; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Decanoic Acids; Dia | 2015 |
Bioenergetic and volume regulatory effects of mitoKATP channel modulators protect against hypoxia-reoxygenation-induced mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Animals; Buffers; Cell Respiration; Decanoic Acids; Diazoxide; Energy Metabo | 2016 |
Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture.
Topics: Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Hypoxia; Ischemic Preconditioning, Myocardial; KA | 2010 |
Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) on hypoxic pulmonary vasoconstriction.
Topics: Animals; Arteries; Coronary Vessels; Decanoic Acids; Glyburide; Heart; Hydroxy Acids; Hypoxia; Immun | 2009 |
[The role of sarcolemmal and mitochondrial K(ATP)-channels in realization of the cardioprotection and antiarrhythmic effect of different regimens of hypobaric adaptation].
Topics: Adaptation, Physiological; Altitude; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic A | 2009 |
Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes.
Topics: Aged; Anesthetics, Inhalation; Blotting, Western; Decanoic Acids; Desflurane; Diabetes Mellitus, Typ | 2011 |
[The effect of 5-HD on expression of PKC-alpha in rats of chronic hypoxic pulmonary hypertension].
Topics: Animals; Decanoic Acids; Hydroxy Acids; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vasc | 2011 |
Effects of mitochondrial K(ATP) modulators on cardioprotection induced by chronic high altitude hypoxia in rats.
Topics: Altitude; Analysis of Variance; Animals; Benzopyrans; Chronic Disease; Decanoic Acids; Diazoxide; Hy | 2002 |
Ischemic preconditioning in chronically hypoxic neonatal rat heart.
Topics: Animals; Animals, Newborn; Body Weight; Decanoic Acids; Heart; Hematocrit; Hydroxy Acids; Hypoxia; I | 2002 |
Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cell Survival; Decanoic Acids; Diazoxide; Hippocamp | 2003 |
Mitochondrial K(ATP) channels and sarcoplasmic reticulum influence cardiac force development under anoxia in the Amazonian armored catfish Liposarcus pardalis.
Topics: Adenosine Triphosphate; Animals; Catfishes; Decanoic Acids; Hydroxy Acids; Hypoxia; In Vitro Techniq | 2003 |
Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro.
Topics: Aged; Anesthetics, Inhalation; ATP-Binding Cassette Transporters; Benzamides; Decanoic Acids; Heart | 2003 |
ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Calcium; Decanoic Acids; Glyburide; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hypoxia; | 2003 |
mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Chick Embryo; Chickens; Decanoic Acids; Diaz | 2005 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Anima | 2008 |
Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle.
Topics: Adenosine Triphosphate; Animals; Calcium; Cerebral Cortex; Cromakalim; Decanoic Acids; Diazoxide; Gl | 2008 |
Preconditioning in immature rabbit hearts: role of KATP channels.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Decanoic Acids; Hydroxy A | 1999 |
Role of an ATP-sensitive potassium channel opener, YM934, in mitochondrial energy production in ischemic/reperfused heart.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzoxazines; Creatine Kinase; Cyclic N-Oxi | 1999 |
Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics?
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Animals, Newborn; Benzopyrans; Cell Hypo | 2000 |
Sarcolemmal and mitochondrial K(atp)channels mediate cardioprotection in chronically hypoxic hearts.
Topics: Animals; Anti-Arrhythmia Agents; Benzamides; Decanoic Acids; Heart; Hemodynamics; Hydroxy Acids; Hyp | 2001 |
Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning.
Topics: Animals; Cell Membrane Permeability; Decanoic Acids; Diazoxide; Enzyme Activation; Hydroxy Acids; Hy | 2002 |
Mitochondrial ATP-sensitive K+ channels influence force development and anoxic contractility in a flatfish, yellowtail flounder Limanda ferruginea, but not Atlantic cod Gadus morhua heart.
Topics: Aerobiosis; Animals; ATP-Binding Cassette Transporters; Decanoic Acids; Diazoxide; Fishes; Flounder; | 2002 |
A1 adenosine receptor overexpression decreases stunning from anoxia-reoxygenation: role of the mitochondrial K(ATP) channel.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Female; Heart; Hydroxy Acids; Hypoxia; In Vitro Tec | 2002 |