5-hydroxydecanoate has been researched along with Anesthesia in 8 studies
5-hydroxydecanoic acid: Potassium Channel Blocker; RN refers to parent cpd
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we sought to investigate the effects of administration of ATP-sensitive K(+) channel (K(ATP)) openers (nicorandil and minoxidil), a specific mitochondrial K(ATP) channel blocker (5-hydroxydecanoate (5-HD)) and a specific sarcolemmal K(ATP) channel blocker (HMR 1883; (1-[5-[2-(5-chloro-o-anisamido)ethyl]-2-methoxyphenyl]sulfonyl-3-methylthiourea) prior to coronary occlusion as well as prior to post-ischemic reperfusion on survival rate, ischemia-induced and reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.73 | Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model? ( Das, B; Sarkar, C, 2005) |
| "We investigated the effects of administration of non-hypotensive doses of ATP-sensitive K+ channel (K(ATP)) openers (nicorandil and aprikalim), and a specific mitochondrial K(ATP) channel blocker (5-hydroxydecanoate) prior to and during coronary occlusion as well as prior to and during post-ischemic reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and myocardial infarct size in anesthetized albino rabbits." | 3.71 | Selective mitochondrial K(ATP) channel activation results in antiarrhythmic effect during experimental myocardial ischemia/reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2002) |
| "Oxytocin (OXT) pretreatment protects the heart during ischemia-reperfusion injury by activating ATP-dependent potassium (K(ATP)) channels." | 1.38 | Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart? ( Das, B; Sarkar, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grossini, E | 1 |
| Pollesello, P | 1 |
| Bellofatto, K | 1 |
| Sigaudo, L | 1 |
| Farruggio, S | 1 |
| Origlia, V | 1 |
| Mombello, C | 1 |
| Mary, DA | 1 |
| Valente, G | 1 |
| Vacca, G | 1 |
| Baharvand, B | 1 |
| Dehaj, ME | 1 |
| Rasoulian, B | 1 |
| Namdari, M | 1 |
| Shikhani, Y | 1 |
| Kiani, AA | 1 |
| Das, B | 3 |
| Sarkar, C | 3 |
| Pagliaro, P | 1 |
| Chiribiri, A | 1 |
| Rastaldo, R | 1 |
| Mancardi, D | 1 |
| Penna, C | 1 |
| Gattullo, D | 1 |
| Losano, G | 1 |
| Vajda, S | 1 |
| Baczkó, I | 1 |
| Leprán, I | 1 |
| Karanth, KS | 1 |
| Grover, GJ | 1 |
| Sleph, PG | 1 |
| Dzwonczyk, S | 1 |
8 other studies available for 5-hydroxydecanoate and Anesthesia
| Article | Year |
|---|---|
Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats.
Topics: Anesthesia; Animals; Apoptosis; bcl-2-Associated X Protein; Biopsy; Blood Flow Velocity; Caspase 3; | 2014 |
Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzophenanthridines; Calcitonin | 2009 |
Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart?
Topics: Anesthesia; Animals; Decanoic Acids; Electrocardiography; Energy Metabolism; Enzyme Inhibitors; Hear | 2012 |
Ischemic preconditioning changes the pattern of coronary reactive hyperemia regardless of mitochondrial ATP-sensitive K(+) channel blockade.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Decanoic | 2002 |
Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model?
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; ATP-Binding Cassett | 2005 |
Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Anesthesia; Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Blood Pressure | 2007 |
Selective mitochondrial K(ATP) channel activation results in antiarrhythmic effect during experimental myocardial ischemia/reperfusion in anesthetized rabbits.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressur | 2002 |
Pharmacologic profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Benzopyrans; Blood Pressure; Cardiovascular Agents; Cor | 1990 |