5-hydroxy-1-methylhydantoin and Uremia

5-hydroxy-1-methylhydantoin has been researched along with Uremia* in 1 studies

Other Studies

1 other study(ies) available for 5-hydroxy-1-methylhydantoin and Uremia

Article	Year
Creatol (5-hydroxycreatinine), a new toxin candidate in uremic patients. Experientia, 1990, May-15, Volume: 46, Issue:5 Both 5-hydroxy-1-methylhydantoin (3) and the hitherto unrecognized 5-hydroxycreatinine (2-amino-5-hydroxy-1-methyl-imidazol-4(5H)-one or creatol) (6) can be isolated from the urine of uremic patients, in whom these compounds probably arise as oxidative metabolites of creatinine (1). The enhanced production of the well-known uremic toxin, methylguanidine (8), from creatinine (1) in such patients, almost certainly occurs via the newly recognized metabolite. Topics: Chemical Phenomena; Chemistry; Creatinine; Female; Humans; Hydantoins; Magnetic Resonance Spectroscopy; Male; Methylguanidine; Toxins, Biological; Uremia	1990

Article

Year

Creatol (5-hydroxycreatinine), a new toxin candidate in uremic patients.

Experientia, 1990, May-15, Volume: 46, Issue:5

Both 5-hydroxy-1-methylhydantoin (3) and the hitherto unrecognized 5-hydroxycreatinine (2-amino-5-hydroxy-1-methyl-imidazol-4(5H)-one or creatol) (6) can be isolated from the urine of uremic patients, in whom these compounds probably arise as oxidative metabolites of creatinine (1). The enhanced production of the well-known uremic toxin, methylguanidine (8), from creatinine (1) in such patients, almost certainly occurs via the newly recognized metabolite.

Topics: Chemical Phenomena; Chemistry; Creatinine; Female; Humans; Hydantoins; Magnetic Resonance Spectroscopy; Male; Methylguanidine; Toxins, Biological; Uremia

1990