5-fluorouridine has been researched along with Colonic Neoplasms in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Callan, B; Callan, JF; Gao, J; Griffith, DM; Logan, KA; Love, M; McHale, AP; McKaig, T; Nesbitt, H; Taylor, M | 1 |
| Bonaterra, GA; Farhat, A; Kinscherf, R; Malecki, E; Rosemeyer, H; Röthlein, D; Schmitt, J; Wolf, M | 1 |
| Banerjee, D; Bertino, JR; Cheng, YC; Gorlick, R; Humeniuk, R; Kemeny, N; Menon, LG; Mishra, PJ; Pizzorno, G; Rode, W; Sowers, R | 1 |
| HAHN, RG; MOERTEL, CG; REITEMEIER, RJ | 1 |
| Canaparo, R; Casale, F; Costa, M; Eandi, M; Fornari, G; Mairone, L; Muntoni, E; Pepa, CD; Serpe, L; Zara, GP | 1 |
| Agarwal, R; Ardalan, B; Patel, M | 1 |
| Cricca, S; de Bruin, M; Laan, AC; Peters, GJ; Temmink, OH; Turksma, AW | 1 |
| Gustavsson, B; Hafström, L | 1 |
| Houghton, JA; Houghton, PJ | 1 |
| Benvenuto, J; Drewinko, B; Freireich, EJ; Ho, DH; Loo, TL; Yang, LY | 1 |
| Glazer, RI; Hartman, KD | 1 |
| Glazer, RI; Lloyd, LS | 1 |
| Chen, TB; Huzak, M; Macura, S; Vuk-Pavlović, S | 1 |
| Allegra, CJ; Chu, E | 1 |
| Bajzer, Z; Chen, TB; Macura, S; Vuk-Pavlovic, S | 1 |
| Hoshi, A; Iigo, M; Nishikata, K | 1 |
| Goldenberg, DM; Sharkey, RM; Shih, LB; Xuan, H | 1 |
| De Clercq, E; Iigo, M; Nakajima, Y; Nishikata, K; Szabolcs, A; Szinai, I; Veres, Z | 1 |
| Inaba, M; Mitsuhashi, J; Ozawa, S | 1 |
| Chisholm, EM; Finan, PJ; Giles, GR; Woodhouse, L | 2 |
| Aigner, KR; Danenberg, PV; Link, KH; Peschau, K; Schwemmle, K; Warthona, M | 1 |
1 review(s) available for 5-fluorouridine and Colonic Neoplasms
| Article | Year |
|---|---|
Treatment of cultured human colon carcinoma cells with fluorinated pyrimidines.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Culture Media; Drug Evaluation, Preclinical; Fluorouracil; Humans; Tegafur; Thymidine; Uridine | 1980 |
1 trial(s) available for 5-fluorouridine and Colonic Neoplasms
| Article | Year |
|---|---|
Plasma concentrations of 5-fluorouracil and its metabolites in colon cancer patients.
Topics: Adult; Aged; Area Under Curve; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Kinetics; Leucovorin; Male; Middle Aged; Uridine | 2004 |
20 other study(ies) available for 5-fluorouridine and Colonic Neoplasms
| Article | Year |
|---|---|
A single microbubble formulation carrying 5-fluorouridine, Irinotecan and oxaliplatin to enable FOLFIRINOX treatment of pancreatic and colon cancer using ultrasound targeted microbubble destruction.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Mice; Microbubbles; Oxaliplatin; Pancreatic Neoplasms; Treatment Outcome; Uridine | 2021 |
Synthesis of 5-fluorouridine nucleolipid derivatives and their cytostatic/cytotoxic activities on human HT-29 colon carcinoma cells.
Topics: Antineoplastic Agents; Cell Survival; Colonic Neoplasms; HT29 Cells; Humans; Microscopy, Confocal; Uridine | 2013 |
Decreased levels of UMP kinase as a mechanism of fluoropyrimidine resistance.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Nucleoside-Phosphate Kinase; RNA Interference; Uridine | 2009 |
COMPARISON OF 5-FLUOROURACIL (NSC-19893) AND 2'-DEOXY-5-FLUOROURIDINE (NSC-27640) IN TREATMENT OF PATIENTS WITH ADVANCED ADENOCARCINOMA OF COLON OR RECTUM.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Deoxyuridine; Drug Therapy; Fluorouracil; Humans; Nucleosides; Palliative Care; Rectal Neoplasms; Rectum; Toxicology; Uridine | 1965 |
Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Irinotecan; Nucleic Acids; Organoplatinum Compounds; Oxaliplatin; Uridine | 2004 |
Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.
Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Floxuridine; Humans; Kinetics; Pyrimidines; Substrate Specificity; Thymidine Phosphorylase; Uridine; Uridine Phosphorylase | 2007 |
Adjuvant and palliative treatment of colorectal cancer with fluorinated pyrimidines. A pharmacological and clinical review.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Fluorine; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Prognosis; Pyrimidines; Rectal Neoplasms; Uridine | 1981 |
On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Male; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous; Uridine | 1980 |
In vitro translation of messenger RNA following exposure of human colon carcinoma cells in culture to 5-fluorouracil and 5-fluorouridine.
Topics: Cell Line; Centrifugation, Density Gradient; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Humans; Protein Biosynthesis; RNA, Messenger; Uridine | 1983 |
Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture.
Topics: Cell Nucleus; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Neoplasms, Experimental; RNA, Neoplasm; Uridine | 1982 |
Somatostatin analogue octreotide modulates metabolism and effects of 5-fluorouracil and 5-fluorouridine in human colon cancer spheroids.
Topics: Adenocarcinoma; Amino Acid Sequence; Cell Cycle; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorine; Fluorouracil; G1 Phase; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Octreotide; Receptors, Somatostatin; Resting Phase, Cell Cycle; RNA, Ribosomal; S Phase; Tumor Cells, Cultured; Uridine | 1994 |
The role of thymidylate synthase in cellular regulation.
Topics: Antineoplastic Agents; Blotting, Southern; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Fluorodeoxyuridylate; Gene Expression Regulation, Neoplastic; Humans; Polymerase Chain Reaction; Precipitin Tests; Protein Biosynthesis; RNA-Binding Proteins; RNA, Messenger; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured; Uridine; Uridine Monophosphate | 1996 |
Differences in metabolism of 5-fluorouracil and 5-fluorouridine and regulation by glucosamine in human colon cancer multicell tumor spheroids.
Topics: Body Fluid Compartments; Colonic Neoplasms; Fluorouracil; Glucosamine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Nonlinear Dynamics; Phosphates; Spheroids, Cellular; Uridine | 1999 |
In vivo antitumor effects of fluoropyrimidines on colon adenocarcinoma 38 and enhancement by leucovorin.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Cell Division; Colonic Neoplasms; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leucovorin; Male; Mice; Mice, Inbred Strains; Thymidylate Synthase; Uridine | 1992 |
A fluorouridine-anti-CEA immunoconjugate is therapeutically effective in a human colonic cancer xenograft model.
Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Cell Survival; Colonic Neoplasms; Dextrans; Drug Carriers; Humans; Immunoglobulin Fc Fragments; Mice; Mice, Nude; Neoplasm Transplantation; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured; Uridine | 1990 |
Differential effects of 2,2'-anhydro-5-ethyluridine, a uridine phosphorylase inhibitor, on the antitumor activity of 5-fluorouridine and 5-fluoro-2'-deoxyuridine.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Interactions; Floxuridine; Fluorouracil; Humans; Kinetics; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Pentosyltransferases; Thymidine Phosphorylase; Tumor Cells, Cultured; Uridine; Uridine Phosphorylase | 1990 |
Kinetic analysis of 5-fluorouracil action against various cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Colonic Neoplasms; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Kidney Neoplasms; Leukemia P388; Mice; RNA, Ribosomal; S Phase; Time Factors; Uridine | 1990 |
Incorporation of intermediary products of 5-FU anabolism into colorectal cancer.
Topics: Aged; Colon; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Intestinal Mucosa; Male; Rectal Neoplasms; Uridine | 1986 |
The relationship between plasma pharmacokinetics and tissue metabolites of 5-fluorouracil (5-FU) in patients with colorectal cancer.
Topics: Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Kinetics; Male; Middle Aged; Rectal Neoplasms; Uridine | 1987 |
Concentration and time dependence of the toxicity of fluorinated pyrimidines to HT 29 colorectal carcinoma cells.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Rectal Neoplasms; Time Factors; Tumor Cells, Cultured; Uridine | 1988 |