5-fluoropyrimidine has been researched along with Colorectal Neoplasms in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Abdhaghighi, MJ; Jalali, H; Janbabaei, G; Negarandeh, R; Nosrati, A; Saghafi, F; Salehifar, E | 1 |
| Dong, J; Gui, Y; Hou, W; Hu, S; Li, Y; Li, Z; Tian, P; Wang, S; Wang, X; Zhang, Y; Zhou, T | 1 |
| Arrowsmith, ER; Bajetta, E; Del Prete, SA; Fuchs, CS; Hwang, J; Jin, J; Malek, K; Ng, K; Ryan, DP; Sedova, M; Sharma, S; Tabernero, J | 1 |
| Barrett, A; Chu, GS; Epurescu, D; Jennings, BA; Keane, M; Loke, YK; Skinner, J; Turner, R; Willis, G | 1 |
| Adams, R; Bridgewater, J; Fisher, D; Grenader, T; Kaplan, R; Maughan, T; Nash, S | 1 |
| Bocci, G; Kerbel, RS | 1 |
| Bacon, O; Barat, A; Belle, S; Betge, J; Byrne, AT; Cordes, M; Ebert, MP; Gaiser, T; Härtel, N; Hennessy, B; Hielscher, T; Hofheinz, RD; Kay, EW; Kripp, M; Lambrechts, D; Murphy, V; Neerincx, M; Prehn, JH; Schulte, N; Van Grieken, NC; Verheul, HM; Ylstra, B; Zhan, T | 1 |
| Cavalli, F; Saletti, P; Sessa, C | 1 |
| Bao, HY; Chen, J; Deng, J; Fang, WJ; Huang, S; Mou, HB; Shen, P; Shi, GM; Xu, N; Yu, LF; Zhang, XC | 1 |
| Boku, N; Machida, N; Toda, Y | 1 |
| Ng, S; O'bichere, A; Platell, C; Tebbutt, N | 1 |
| Calin, GA; Dubois, RN; Ellis, LM; Eng, C; Gu, J; Hawk, ET; Hildebrandt, MA; Huang, M; Lin, J; Lin, M; Wang, D; Wu, X | 1 |
| Banerjee, D; Bertino, JR | 1 |
| Chu, QS; Damle, B; DeCillis, AP; Denis, L; Hammond, LA; Letrent, SP; Molpus, K; Ochoa, L; Rha, SY; Roedig, B; Rowinsky, EK; Schwartz, G | 1 |
| Adleff, V; Budai, B; Czeglédi, F; Gyergyay, F; Hitre, E; Kralovánszky, J; Láng, I | 1 |
| Barbado, M; Boisdron-Celle, M; Gamelin, E; Lorimier, G; Morel, A; Preisser, L; Verriele, V | 1 |
| Bridgewater, J; Glynne-Jones, R; Harrison, M; Propper, D; Stebbing, J | 1 |
| Schwartz, EL; Wadler, S | 1 |
| Misset, JL | 1 |
| Baker, SD; Burks, K; Donehower, RC; Grochow, LB; O'Reilly, S; Rowinsky, EK | 1 |
| Abe, J; Asada, Y; Fujisawa, K; Iida, Y; Kasahara, Y; Mitsui, T; Miura, S; Munemoto, Y; Saito, H | 1 |
| Machover, D | 1 |
4 review(s) available for 5-fluoropyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect.
Topics: Administration, Metronomic; Alkylating Agents; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Female; Forecasting; Humans; Immunity, Cellular; Pyrimidines; Randomized Controlled Trials as Topic; Tubulin Modulators | 2016 |
[The role of oral fluoropyrimidines in colorectal cancer treatment--a review].
Topics: Administration, Oral; Antineoplastic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Humans; Pyrimidines; Quality of Life | 2010 |
Is the measurement of thymidylate synthase to determine suitability for treatment with 5-fluoropyrimidines ready for prime time?
Topics: Blotting, Western; Colorectal Neoplasms; Disease Progression; Hepatic Artery; Humans; Neoplasms; Pyrimidines; Thymidylate Synthase | 2003 |
Developments of the fluoropyrimidines as inhibitors of thymidylate synthetase: pharmacologic and clinical aspects.
Topics: Animals; Antineoplastic Agents; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Organoplatinum Compounds; Prodrugs; Pyrimidines; Thymidylate Synthase | 1991 |
8 trial(s) available for 5-fluoropyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
Phase II study of everolimus in patients with metastatic colorectal adenocarcinoma previously treated with bevacizumab-, fluoropyrimidine-, oxaliplatin-, and irinotecan-based regimens.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Disease-Free Survival; DNA Mutational Analysis; Drug Resistance, Neoplasm; Everolimus; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Phosphatidylinositol 3-Kinases; Prospective Studies; Proto-Oncogene Proteins B-raf; Pyrimidines; Sirolimus; Treatment Outcome | 2013 |
Evaluating predictive pharmacogenetic signatures of adverse events in colorectal cancer patients treated with fluoropyrimidines.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Mutation; Pharmacogenetics; Pyrimidines; Retrospective Studies | 2013 |
Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Pyrimidines; Survival Rate; Young Adult | 2016 |
Phase II study of FOLFIRI regimen in patients with advanced colorectal cancer refractory to fluoropyrimidine and oxaliplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; China; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nausea; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Survival; Vomiting; Young Adult | 2011 |
Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Orotate Phosphoribosyltransferase; Oxonic Acid; Pyridines; Pyrimidines; Stomach Neoplasms; Tegafur; Time Factors | 2004 |
A phase II study to determine the ability of gefitinib to reverse fluoropyrimidine resistance in metastatic colorectal cancer (the INFORM study).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Male; Middle Aged; Pyrimidines; Quinazolines | 2008 |
High-dose topotecan with granulocyte-colony stimulating factor in fluoropyrimidine-refractory colorectal cancer: a phase II and pharmacodynamic study.
Topics: Adult; Aged; Colorectal Neoplasms; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukocyte Count; Male; Middle Aged; Neutrophils; Pyrimidines; Topotecan; Treatment Failure | 1998 |
Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: Association between host or tumor factors and survival.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemotherapy, Adjuvant; Colorectal Neoplasms; Complement C3; Complement C4; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Mitomycin; Neoplasm Proteins; Phytohemagglutinins; Polysaccharides; Postoperative Period; Prognosis; Proportional Hazards Models; Pyrimidines; Survival Analysis; Survival Rate | 2002 |
10 other study(ies) available for 5-fluoropyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
Evaluation of adverse effects of chemotherapy regimens of 5-fluoropyrimidines derivatives and their association with DPYD polymorphisms in colorectal cancer patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Cross-Sectional Studies; Dihydrouracil Dehydrogenase (NADP); Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pyrimidines | 2020 |
Efficacy of Chinese herbal injections combined with fluoropyrimidine and oxaliplatin-based chemotherapy for advanced colorectal cancer: A protocol for systematic review and meta-analysis of randomized controlled trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Drugs, Chinese Herbal; Humans; Injections; Meta-Analysis as Topic; Neoplasm Staging; Oxaliplatin; Phytotherapy; Pyrimidines; Randomized Controlled Trials as Topic; Research Design; Systematic Reviews as Topic; Treatment Outcome | 2020 |
Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyrimidines; Retrospective Studies; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography | 2016 |
Commentary 2008: 25 or 50 years later?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Colorectal Neoplasms; Fluorouracil; Humans; Liver Neoplasms, Experimental; Medical Oncology; Pyrimidines | 2008 |
Changing management and survival in patients with stage IV colorectal cancer.
Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Antineoplastic Agents; Australia; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Colostomy; Deoxycytidine; Female; Fluorouracil; Humans; Irinotecan; Male; Multivariate Analysis; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Proportional Hazards Models; Pyrimidines; Radiotherapy, Adjuvant; Survival Rate | 2011 |
Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients.
Topics: Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; Disease-Free Survival; Female; Genotype; Humans; Male; MicroRNAs; Middle Aged; Neoplasm Staging; Polymorphism, Single Nucleotide; Prognosis; Pyrimidines; Recurrence; Treatment Outcome | 2012 |
[The clinical importance of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the 5-fluoropyrimidine-based therapy of metastatic colorectal tumours].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Colorectal Neoplasms; Cytosine; Female; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Predictive Value of Tests; Prognosis; Pyrimidines; Survival Analysis; Thymine | 2004 |
Tumor quantification of several fluoropyrimidines resistance gene expression with a unique quantitative RT-PCR method. Implications for pretherapeutic determination of tumor resistance phenotype.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma; Colorectal Neoplasms; DNA Primers; DNA, Complementary; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Oligonucleotide Array Sequence Analysis; Phenotype; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Role of interferon as a modulator of fluoropyrimidines: reply to a recent editorial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Interferon-alpha; Interferon-beta; Pyrimidines | 1997 |
[Chemotherapy of advanced colorectal cancers after failure of a treatment with fluoropyrimidine].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Enzyme Inhibitors; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Thymidylate Synthase; Treatment Failure | 1997 |