Page last updated: 2024-09-03

5-fluorodihydrouracil and Colorectal Cancer

5-fluorodihydrouracil has been researched along with Colorectal Cancer in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amadori, D; Amatori, F; Danesi, R; Del Tacca, M; Di Paolo, A; Flamini, E; Ibrahim, T; Mercatali, L; Ravaioli, E; Sacanna, E1
Amstutz, U; Büchel, B; Bühr, C; Largiadèr, CR; Rhyn, P; Schürch, S1
Bocci, G; Ciccolini, J; Danesi, R; Di Paolo, A; Iliadis, A; Lacarelle, B; Marouani, H; Woloch, C1
Amadori, D; Cionini, L; Danesi, R; Del Tacca, M; Di Paolo, A; Falcone, A; Ibrahim, T; Mini, E; Vannozzi, F1
Amatori, F; Bocci, G; Danesi, R; Del Tacca, M; Di Donato, S; Di Paolo, A; Falcone, A; Federici, F; Iannopollo, M; Lastella, M; Lencioni, M; Orlandini, C; Ricci, S1
Allegrini, G; Barsanti, G; Battistoni, M; Bocci, G; Conte, PF; Danesi, R; Del Tacca, M; Di Paolo, AD; Falcone, A; Innocenti, F; Melosi, A1

Trials

2 trial(s) available for 5-fluorodihydrouracil and Colorectal Cancer

ArticleYear
Time-dependent pharmacokinetics of 5-fluorouracil and association with treatment tolerability in the adjuvant setting of colorectal cancer.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged

2012
Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidoreductases

2000

Other Studies

4 other study(ies) available for 5-fluorodihydrouracil and Colorectal Cancer

ArticleYear
LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Chromatography, Liquid; Colorectal Neoplasms; Drug Monitoring; Drug Stability; Female; Fluorouracil; Humans; Linear Models; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Uracil

2013
Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:15

    Topics: Aged; Biomarkers; Chemotherapy, Adjuvant; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Humans; Logistic Models; Male; Middle Aged; Models, Biological; Nausea; Retrospective Studies; Vomiting

2012
Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Administration Schedule; Drug Monitoring; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Middle Aged; Predictive Value of Tests; Regression Analysis

2002
5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, May-01, Volume: 14, Issue:9

    Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Multivariate Analysis; Retrospective Studies

2008