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5-ethynyl-1-ribofuranosylimidazole-4-carboxamide and Leukemia L 1210

5-ethynyl-1-ribofuranosylimidazole-4-carboxamide has been researched along with Leukemia L 1210 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balzarini, J; Bohman, C; De Clercq, E; Fridland, A; Herdewijn, P; Horská, K; Karlsson, A; Van Aerschot, A; Votruba, I; Wang, L1
Balzarini, J; De Clercq, E; Knauss, E; Matsuda, A; Stet, L; Wiebe, L1
Matsuda, A; Minakawa, N1
Matsuda, A; Minakawa, N; Sasaki, T; Takeda, T; Ueda, T1
Matsuda, A; Minakawa, N; Sasaki, T; Ueda, T1

Other Studies

5 other study(ies) available for 5-ethynyl-1-ribofuranosylimidazole-4-carboxamide and Leukemia L 1210

ArticleYear
Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
    The Journal of biological chemistry, 1993, Nov-25, Volume: 268, Issue:33

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Division; Deoxyguanine Nucleotides; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Leukemia L1210; Lymphocytes; Mice; Mycophenolic Acid; Purine Nucleotides; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured

1993
Metabolism of EICAR (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide), a potent inhibitor of inosinate dehydrogenase.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Animals; Antineoplastic Agents; IMP Dehydrogenase; Kinetics; Leukemia L1210; Mice; Ribonucleosides; Tritium; Tumor Cells, Cultured

1998
Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
    Current medicinal chemistry, 1999, Volume: 6, Issue:7

    Topics: Animals; Antineoplastic Agents; Catalysis; Drug Design; Fluorouracil; Humans; IMP Dehydrogenase; Inhibitory Concentration 50; Leukemia L1210; Models, Chemical; Ribavirin; Ribonucleosides; Structure-Activity Relationship; Tumor Cells, Cultured

1999
Nucleosides and nucleotides. 96. Synthesis and antitumor activity of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Humans; Leukemia L1210; Leukemia P388; Mice; Ribonucleosides; Structure-Activity Relationship

1991
The design, synthesis and antileukemic activity of 5-alkynyl-1-beta-D-ribofuranosylimidazole-4-carboxamides.
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:7

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Ribonucleosides; Tumor Cells, Cultured

1988