5-dimethylamiloride has been researched along with Disease Models, Animal in 7 studies
5-dimethylamiloride: has anti-HIV-1 activity
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Benzolamide dose-dependently inhibited CO(2)-induced hyperemia and at 100 nmol/L inhibited CO(2)-induced intracellular acidification." | 3.73 | Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum. ( Akiba, Y; Engel, E; Ghayouri, S; Guth, PH; Kaunitz, JD; Mizumori, M; Swenson, ER; Takeuchi, T, 2006) |
| "The inhibition of Na(+)-H+ exchange (NHE) with amiloride analogues in vitro has been shown to prevent reperfusion arrhythmias and additional cell necrosis." | 3.69 | Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. ( Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Behan, AT | 1 |
| Breen, B | 1 |
| Hogg, M | 1 |
| Woods, I | 1 |
| Coughlan, K | 1 |
| Mitchem, M | 1 |
| Prehn, JH | 1 |
| Akiba, Y | 1 |
| Ghayouri, S | 1 |
| Takeuchi, T | 1 |
| Mizumori, M | 1 |
| Guth, PH | 1 |
| Engel, E | 1 |
| Swenson, ER | 1 |
| Kaunitz, JD | 1 |
| Gunawardana, SC | 1 |
| Head, WS | 1 |
| Piston, DW | 1 |
| Fukuta, M | 1 |
| Wakida, Y | 1 |
| Iwa, T | 1 |
| Uesugi, M | 1 |
| Kobayashi, T | 1 |
| Salinas, P | 1 |
| Gil-Loyzaga, P | 1 |
| Barrigon, S | 1 |
7 other studies available for 5-dimethylamiloride and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration.
Topics: Acid Sensing Ion Channels; Acids; Amiloride; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cell | 2013 |
Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum.
Topics: Amiloride; Animals; Benzolamide; Blood Flow Velocity; Capsaicin; Carbon Dioxide; Carbonic Anhydrase | 2006 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease | 2008 |
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Co | 1996 |
Ultrastructural evidence of the protective effect of Na+/H+ exchange inhibition on the in vitro damage induced by ischaemia reperfusion in the interventricular septum of the rabbit heart.
Topics: Amiloride; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; | 2000 |