5-carboxamidotryptamine has been researched along with Muscle Contraction in 43 studies
5-carboxamidotryptamine: agonist of 5-HT receptor; structure given in first source
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Intrathecal injection of 5-methoxy-N,N'-dimethyltryptamine (5-MeODMT), (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) or 2,5-dimethoxy-alpha,4-dimethylbenzene ethamine hydrochloride (DOM) produced dose-related back muscle contractions (BMC) and wet dog shakes (WDS) which were both markedly attenuated by intraperitoneal pretreatment with either ritanserin (1 mg kg-1), ketanserin (0." | 3.68 | Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats. ( Fone, KC; Marsden, CA; Robinson, AJ, 1991) |
| "Subarachnoid hemorrhage was induced in male Sprague-Dawley rats by the injection of 250 μl of autologous blood into the basal cisterns." | 1.37 | Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats. ( Edvinsson, L; Larsen, CC; Povlsen, GK; Rasmussen, MN, 2011) |
| "Pretreatment with ketanserin (10 microM), a 5-HT2 antagonist, tropisetron (1 microM), a 5-HT3/4 antagonist, SDZ 216-525 (1 to 10 microM) and pindobind (10 microM), both selective 5-HT1A antagonists, or capsaicin (10 microM), which depletes sensory nerves from neuropeptides, had no effect on the inhibition of the cholinergic contraction by 8-OH-DPAT (10 to 30 microM)." | 1.30 | The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro. ( De Leyn, P; Demedts, MG; Deneffe, G; Dupont, LJ; Pype, JL; Verleden, GM, 1998) |
| "Sumatriptan did not cause relaxation." | 1.28 | Sumatriptan contracts large coronary arteries of beagle dogs through 5-HT1-like receptors. ( Kaumann, AJ; Parsons, AA; Raval, P; Stutchbury, C, 1992) |
| "5." | 1.28 | Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery. ( Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (16.28) | 18.7374 |
| 1990's | 24 (55.81) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wainscott, DB | 1 |
| Cohen, ML | 2 |
| Schenck, KW | 1 |
| Audia, JE | 1 |
| Nissen, JS | 1 |
| Baez, M | 2 |
| Kursar, JD | 2 |
| Lucaites, VL | 1 |
| Nelson, DL | 1 |
| Bolognesi, ML | 1 |
| Budriesi, R | 1 |
| Cavalli, A | 1 |
| Chiarini, A | 1 |
| Gotti, R | 1 |
| Leonardi, A | 1 |
| Minarini, A | 1 |
| Poggesi, E | 1 |
| Recanatini, M | 1 |
| Rosini, M | 1 |
| Tumiatti, V | 1 |
| Melchiorre, C | 1 |
| Perrone, R | 3 |
| Berardi, F | 3 |
| Colabufo, NA | 3 |
| Lacivita, E | 3 |
| Leopoldo, M | 3 |
| Tortorella, V | 2 |
| Contino, M | 2 |
| Niso, M | 1 |
| Larsen, CC | 1 |
| Povlsen, GK | 1 |
| Rasmussen, MN | 1 |
| Edvinsson, L | 1 |
| Rekik, M | 1 |
| Lluel, P | 1 |
| Palea, S | 1 |
| Jähnichen, S | 1 |
| Radtke, OA | 1 |
| Pertz, HH | 1 |
| Janssen, P | 1 |
| Prins, NH | 1 |
| Peeters, PJ | 1 |
| Zuideveld, KP | 1 |
| Lefebvre, RA | 2 |
| Delesalle, C | 1 |
| Deprez, P | 1 |
| Schuurkes, JA | 1 |
| Beg, SS | 1 |
| Hansen-Schwartz, JA | 1 |
| Vikman, PJ | 1 |
| Xu, CB | 1 |
| Edvinsson, LI | 1 |
| Mizuno, R | 1 |
| Ohhashi, T | 1 |
| Miyamoto, A | 1 |
| Sakota, T | 1 |
| Nishio, A | 1 |
| Buchheit, KH | 1 |
| Buhl, T | 1 |
| Choppin, A | 2 |
| O'Connor, SE | 2 |
| Cushing, DJ | 1 |
| Schenck, K | 1 |
| Carter, D | 1 |
| Champney, M | 1 |
| Hwang, B | 1 |
| Eglen, RM | 1 |
| Fujiwara, T | 1 |
| Chiba, S | 1 |
| Valentin, JP | 1 |
| Bonnafous, R | 1 |
| John, GW | 1 |
| Sevcík, J | 1 |
| Ruzicka, V | 1 |
| Slánsky, J | 1 |
| Masek, K | 1 |
| Ellwood, AJ | 1 |
| Curtis, MJ | 1 |
| Teng, GQ | 1 |
| Williams, J | 1 |
| Zhang, L | 1 |
| Purdy, R | 1 |
| Pearce, WJ | 1 |
| Dupont, LJ | 1 |
| Pype, JL | 1 |
| Demedts, MG | 1 |
| De Leyn, P | 1 |
| Deneffe, G | 1 |
| Verleden, GM | 1 |
| Hemedah, M | 1 |
| Coupar, IM | 1 |
| Mitchelson, FJ | 1 |
| Gidener, S | 1 |
| Gümüştekin, M | 1 |
| Kirkali, Z | 1 |
| Kitazawa, T | 1 |
| Yamada, Y | 1 |
| Iwano, H | 1 |
| Yokota, H | 1 |
| Yuasa, A | 1 |
| Taneike, T | 1 |
| Maassen VanDenBrink, A | 1 |
| Reekers, M | 1 |
| Bax, WA | 1 |
| Saxena, PR | 2 |
| Lucchelli, A | 1 |
| Santagostino-Barbone, MG | 1 |
| D'Agostino, G | 1 |
| Masoero, E | 1 |
| Tonini, M | 1 |
| Parsons, AA | 3 |
| Stutchbury, C | 1 |
| Raval, P | 1 |
| Kaumann, AJ | 1 |
| Tadipatri, S | 1 |
| van Heuven-Nolsen, D | 1 |
| Feniuk, W | 3 |
| Gürdal, H | 1 |
| Tulunay, FC | 1 |
| Fone, KC | 1 |
| Robinson, AJ | 1 |
| Marsden, CA | 1 |
| Templeton, AG | 1 |
| McGrath, JC | 2 |
| Whittle, MJ | 2 |
| Hill, JM | 1 |
| Kaufman, MP | 1 |
| Boeckxstaens, GE | 1 |
| Pelckmans, PA | 1 |
| Rampart, M | 1 |
| Bogers, JJ | 1 |
| Verbeuren, TJ | 1 |
| Herman, AG | 1 |
| Van Maercke, YM | 1 |
| Trevethick, MA | 1 |
| Humphrey, PP | 2 |
| MacLennan, SJ | 1 |
| Whalley, ET | 2 |
| Demolle, D | 1 |
| Van Coevorden, A | 1 |
| Boeynaems, JM | 1 |
| Perren, MJ | 1 |
| Watts, AD | 1 |
| Kalkman, HO | 1 |
| Engel, G | 1 |
| Hoyer, D | 1 |
43 other studies available for 5-carboxamidotryptamine and Muscle Contraction
| Article | Year |
|---|---|
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; | 1993 |
WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; CHO Cells; Clonin | 1999 |
Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
Topics: Animals; Brain; Cell Line; Cricetinae; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Isoxazoles; | 2003 |
Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Topics: Amides; Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Muscle Contraction; Muscle | 2004 |
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pi | 2007 |
Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats.
Topics: Animals; Behavior, Animal; Butadienes; Cerebral Arteries; Endothelin B Receptor Antagonists; Immunoh | 2011 |
5-Hydroxytryptamine potentiates neurogenic contractions of rat isolated urinary bladder through both 5-HT(7) and 5-HT(2C) receptors.
Topics: Animals; Electric Stimulation; Female; In Vitro Techniques; Muscle Contraction; Nervous System; Rats | 2011 |
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation | 2004 |
5-HT7 receptor efficacy distribution throughout the canine stomach.
Topics: Alternative Splicing; Animals; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Gastric Mu | 2004 |
Contractile effects of 5-hydroxytryptamine and 5-carboxamidotryptamine in the equine jejunum.
Topics: Animals; Dose-Response Relationship, Drug; Horses; Jejunum; Muscle Contraction; Serotonin; Serotonin | 2006 |
Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats.
Topics: Algorithms; Animals; Autoradiography; Basilar Artery; Blotting, Western; Capillaries; Cerebral Arter | 2007 |
5-Hydroxytryptamine-induced NO-dependent relaxation in isolated strips of monkey popliteal lymph nodes.
Topics: Animals; Arginine; Aspirin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanseri | 1995 |
Characterization of 5-hydroxytryptamine receptors on the isolated pig basilar artery by functional and radioligand binding studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basilar Artery; Binding, Competitive; Dose-Response | 1994 |
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding | 1994 |
Presence of vasoconstrictor 5HT1-like receptors revealed by precontraction of rabbit isolated mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; In Vitro Techniques; Ma | 1995 |
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.
Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coron | 1994 |
Pre-contraction with histamine and U46619 unmasks a 5-HT1-like receptor in rabbit renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Dose-Response Relations | 1993 |
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter | 1995 |
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models, | 1995 |
Influence of the endothelium and nitric oxide on the contractile responses evoked by 5-HT1D receptor agonists in the rabbit isolated saphenous vein.
Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascu | 1996 |
Which type of 5-hydroxytryptamine receptor mediates relaxation of the longitudinal muscle of guinea pig proximal colon in vitro?
Topics: Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indoles; Ketanse | 1996 |
Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Endot | 1997 |
Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Carotid Artery, Common; Cerebral Arteries; F | 1998 |
The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Capsai | 1998 |
[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum.
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship | 1999 |
Pharmacological analysis of 5-hydroxytryptamine effects on human isolated ureter.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Age | 1999 |
Smooth muscle layer-dependent distribution of 5-hydroxytryptamine(7) receptor in the porcine myometrium.
Topics: 5-Methoxytryptamine; Animals; Cyclic AMP; Female; Muscle Contraction; Muscle, Smooth; Myometrium; Re | 2000 |
Human isolated coronary artery contraction to sumatriptan characterised by the selective 5-HT1B/1D receptor antagonist GR55562.
Topics: Benzamides; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Humans | 2000 |
The interaction of antidepressant drugs with enteric 5-HT7 receptors.
Topics: Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Il | 2000 |
Sumatriptan contracts large coronary arteries of beagle dogs through 5-HT1-like receptors.
Topics: Animals; Arteries; Coronary Vessels; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indol | 1992 |
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)te | 1991 |
Heterogeneous inhibitory effect of nitrendipine on 5-HT-responses in rabbit vascular tissues.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; In Vitro Techniques; Ketanserin; Kinetics; Muscle Contra | 1991 |
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, S | 1991 |
The role of endogenous thromboxane in contractions to U46619, oxygen, 5-HT and 5-CT in the human isolated umbilical artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Female; Hept | 1991 |
Intrathecal serotonin attenuates the pressor response to static contraction.
Topics: Animals; Blood Pressure; Cats; Heart Rate; Injections, Spinal; Mianserin; Muscle Contraction; Recept | 1991 |
Pharmacological characterization of 5-hydroxytryptamine receptors in the canine terminal ileum and ileocolonic junction.
Topics: Animals; Colon; Culture Techniques; Dogs; Female; Ileum; Indoles; Intestinal Mucosa; Ketanserin; Mal | 1990 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; D | 1986 |
5-HT1-like receptors requiring functional cyclo-oxygenase and 5-HT2 receptors independent of cyclo-oxygenase mediate contraction of the human umbilical artery.
Topics: Atmospheric Pressure; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascu | 1989 |
Characterization of the 5-hydroxytryptamine receptor which mediates contraction of the human isolated basilar artery.
Topics: Basilar Artery; Female; Humans; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smoo | 1989 |
Evidence for the presence of 5-HT1-like receptors in rabbit isolated basilar arteries.
Topics: Animals; Basilar Artery; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Indoles; Male; Muscl | 1989 |
Stimulation of aortic smooth muscle prostacyclin by serotonin: role of distinct receptors in contractile and synthetic states.
Topics: Animals; Aorta, Thoracic; Cattle; Cells, Cultured; Epoprostenol; Ketanserin; Methiothepin; Muscle Co | 1989 |
A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists.
Topics: Animals; Aorta; Dogs; In Vitro Techniques; Ketanserin; Methoxamine; Muscle Contraction; Muscle, Smoo | 1985 |
Inhibition of 5-carboxamidotryptamine-induced relaxation of guinea-pig ileum correlates with [125I]LSD binding.
Topics: Animals; Binding, Competitive; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contrac | 1986 |