5-aminoisoquinolinone has been researched along with Reperfusion Injury in 7 studies
5-aminoisoquinolinone: structure in first source
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to investigate the effects of 5-aminoisoquinolinone (5-AIQ), a water-soluble potent inhibitor of poly-(ADP-ribose) polymerase (PARP) in a rat model of liver ischemia-reperfusion injury." | 3.71 | The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat. ( Cuzzocrea, S; McDonald, MC; Mota-Filipe, H; Pinto, R; Sepodes, B; Thiemermann, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hendryk, S | 1 |
| Czuba, ZP | 1 |
| Jedrzejowska-Szypulka, H | 1 |
| Szliszka, E | 1 |
| Phillips, VA | 1 |
| Threadgill, MD | 2 |
| Krol, W | 1 |
| Mota-Filipe, H | 2 |
| Sepodes, B | 1 |
| McDonald, MC | 2 |
| Cuzzocrea, S | 3 |
| Pinto, R | 1 |
| Thiemermann, C | 3 |
| Chatterjee, PK | 1 |
| Chatterjee, BE | 1 |
| Pedersen, H | 1 |
| Sivarajah, A | 1 |
| Brown, PA | 1 |
| Stewart, KN | 1 |
| Khandoga, A | 1 |
| Biberthaler, P | 1 |
| Enders, G | 1 |
| Krombach, F | 1 |
| Mariscalco, MM | 1 |
| Di Paola, R | 1 |
| Genovese, T | 1 |
| Caputi, AP | 1 |
| Threadgill, M | 1 |
| Roesner, JP | 1 |
| Vagts, DA | 1 |
| Iber, T | 1 |
| Eipel, C | 1 |
| Vollmar, B | 1 |
| Nöldge-Schomburg, GF | 1 |
7 other studies available for 5-aminoisoquinolinone and Reperfusion Injury
| Article | Year |
|---|---|
Influence of 5-aminoisoquinolin-1-one (5-AIQ) on neutrophil chemiluminescence in rats with transient and prolonged focal cerebral ischemia and after reperfusion.
Topics: Animals; Brain Ischemia; Disease Models, Animal; DNA Breaks; Free Radicals; Isoquinolines; Luminesce | 2008 |
The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.
Topics: Animals; Cell Survival; Cells, Cultured; gamma-Glutamyltransferase; Humans; Immunohistochemistry; In | 2002 |
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.
Topics: Anesthesia; Animals; Cell Death; Cells, Cultured; Glomerular Filtration Rate; Hydrogen Peroxide; Iso | 2004 |
5-Aminoisoquinolinone, a novel inhibitor of poly(adenosine disphosphate-ribose) polymerase, reduces microvascular liver injury but not mortality rate after hepatic ischemia-reperfusion.
Topics: Animals; Apoptosis; Female; Isoquinolines; Liver; Mice; Mice, Inbred BALB C; Necrosis; Poly(ADP-ribo | 2004 |
Hepatic microcirculation in ischemia/reperfusion: is there a role for poly(adenosine 5'-diphosphate-ribose) polymerases?
Topics: Animals; Isoquinolines; Liver; Liver Circulation; Microcirculation; Poly(ADP-ribose) Polymerase Inhi | 2004 |
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Celiac Artery; Disease Models, Animal; Intercellular Adhesion Molecule-1; Intestine, Small; | 2004 |
Protective effects of PARP inhibition on liver microcirculation and function after haemorrhagic shock and resuscitation in male rats.
Topics: Animals; Isoquinolines; Liver; Male; Microcirculation; Microscopy, Fluorescence; Poly(ADP-ribose) Po | 2006 |