5,8,11,14-eicosatetraynoic acid has been researched along with Muscle Relaxation in 7 studies
5,8,11,14-Eicosatetraynoic Acid: A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eicosatetraynoic acid (50 microM), nordihydroguairetic acid (50 microM) and QUIN (10 microM) do not exert significant inhibitory effects at the level of smooth muscle relaxation mechanisms as isoproterenol-induced relaxation was resistant to inhibition by these agents." | 3.66 | Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. ( Peach, MJ; Singer, HA, 1983) |
| "Indomethacin pretreatment (14 microM, 30 min) potentiated the relaxation response in intact rings." | 1.27 | Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid. ( Peach, MJ; Singer, HA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furchgott, RF | 1 |
| Singer, HA | 2 |
| Peach, MJ | 2 |
| Mostaghim, R | 2 |
| Thomas, G | 2 |
| Ramwell, PW | 2 |
| Maddox, YT | 1 |
| Ramwell, P | 1 |
| Puglisi, L | 1 |
| Salvadori, S | 1 |
| Gabrielli, G | 1 |
| Pasargiklian, R | 1 |
1 review available for 5,8,11,14-eicosatetraynoic acid and Muscle Relaxation
| Article | Year |
|---|---|
The role of endothelium in the responses of vascular smooth muscle to drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Acetylcholine; Adenosine Diphosphate; Adenosine Trip | 1984 |
6 other studies available for 5,8,11,14-eicosatetraynoic acid and Muscle Relaxation
| Article | Year |
|---|---|
Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Cate | 1983 |
Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Aorta, Thoracic; Arachidonic Acid; | 1983 |
Endothelial potentiation of relaxation response to phentolamine in rat thoracic aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Technique | 1988 |
Endothelial potentiation of relaxation response to beta adrenoceptor blocking agents.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dinoprost; D | 1986 |
Induction of vascular relaxation by hydroperoxides.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Chlorobenzoates; Endothelium; Hydroxide | 1986 |
Pharmacology of natural compounds. I. Smooth muscle relaxant activity induced by a Ginkgo biloba L. extract on guinea-pig trachea.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Musc | 1988 |