5,8,11,14-eicosatetraynoic acid has been researched along with Ischemia in 5 studies
5,8,11,14-Eicosatetraynoic Acid: A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A novel active-site directed specific inhibitor of phospholipase A2 (PLA2), 1-hexadecyl-3-trifluoroethylglycero-sn-2-phosphomethanol (MJ33), administered endotracheally co-dispersed in liposomes, significantly reduced the formation of thiobarbituric acid reactive substances (TBARS) in isolated rat lungs subjected to ischemia-reperfusion." | 3.68 | A phospholipase A2 inhibitor decreases generation of thiobarbituric acid reactive substance during lung ischemia-reperfusion. ( al-Mehdi, AB; Dodia, C; Fisher, AB; Jain, MK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, AB | 4 |
| Dodia, C | 3 |
| Ayene, I | 2 |
| al-Mehdi, A | 1 |
| al-Mehdi, AB | 2 |
| Jain, MK | 1 |
| Ayene, IS | 1 |
| Messina, EJ | 1 |
| Weiner, R | 1 |
| Kaley, G | 1 |
| Tan, ZT | 1 |
| Eckenhoff, RG | 1 |
5 other studies available for 5,8,11,14-eicosatetraynoic acid and Ischemia
| Article | Year |
|---|---|
Ischemia-reperfusion injury to the lung.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Hypoxia; Ischemia; Lung; Male; Oxygen; Rats; | 1994 |
A phospholipase A2 inhibitor decreases generation of thiobarbituric acid reactive substance during lung ischemia-reperfusion.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Glycerophosphates; Ischemia; Lipid Peroxidation; Lung; Mal | 1993 |
Inhibition of lung tissue oxidation during ischemia/reperfusion by 2-mercaptopropionylglycine.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Deferoxamine; Ischemia; Lipid Peroxidation; Lung; Male; Ox | 1993 |
Arteriolar reactive hyperemia: modification by inhibitors of prostaglandin synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Bradykinin; Hyperemia; Indomethacin; Ischemia; Male; Micro | 1977 |
Oxygen-dependent lipid peroxidation during lung ischemia.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Eicosanoids; Hydrogen-Ion Concentration; Ischemia; Lipid P | 1991 |