5,8,11,14-eicosatetraynoic acid has been researched along with Blast Crisis in 2 studies
5,8,11,14-Eicosatetraynoic Acid: A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).
Blast Crisis: An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We cultured chronic myelogenous leukemia cells from the peripheral blood of several patients in blast crisis with three inhibitors of lipoxygenases: ETYA, and the more selective A63162 (Abbott) or SC41661A (Searle)." | 1.29 | Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase. ( Anderson, KM; Harris, JE; Jajeh, A; Levin, J; Seed, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, KM | 2 |
| Levin, J | 1 |
| Jajeh, A | 2 |
| Seed, T | 2 |
| Harris, JE | 2 |
| Plate, JM | 1 |
| Meng, J | 1 |
2 other studies available for 5,8,11,14-eicosatetraynoic acid and Blast Crisis
| Article | Year |
|---|---|
Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Apoptosis; Base Sequence; Blast Crisis; Blood C | 1993 |
Selective inhibitors of 5-lipoxygenase reduce CML blast cell proliferation and induce limited differentiation and apoptosis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Antineoplastic Agents; Apoptosis; Blast Crisis; | 1995 |