Compounds > 5-7-dimethoxy-2-phenyl-3-4-dihydro-2H-1-benzopyran-4-one

5-7-dimethoxy-2-phenyl-3-4-dihydro-2H-1-benzopyran-4-one and Colonic-Neoplasms

5-7-dimethoxy-2-phenyl-3-4-dihydro-2H-1-benzopyran-4-one has been researched along with Colonic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 5-7-dimethoxy-2-phenyl-3-4-dihydro-2H-1-benzopyran-4-one and Colonic-Neoplasms

Article	Year
Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities. Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20 It has been previously shown that some flavonoids inhibit NF-κB; however, the structure-activity relationships between chalcone, flavanone, flavone, and isoflavone derivatives and their TNFα induced NF-κB inhibitory effects on HCT116 human colon cancer cells have not yet been reported. Therefore, in this study, the effects of flavonoid structure on inhibition of NF-κB were investigated. Based on the combined results of this study, the structure of the flavonoids was shown to affect NF-κB activation. Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Flavonoids; Humans; Models, Molecular; NF-kappa B; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2011

Article

Year

Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities.

Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

It has been previously shown that some flavonoids inhibit NF-κB; however, the structure-activity relationships between chalcone, flavanone, flavone, and isoflavone derivatives and their TNFα induced NF-κB inhibitory effects on HCT116 human colon cancer cells have not yet been reported. Therefore, in this study, the effects of flavonoid structure on inhibition of NF-κB were investigated. Based on the combined results of this study, the structure of the flavonoids was shown to affect NF-κB activation.

Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Flavonoids; Humans; Models, Molecular; NF-kappa B; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2011