5,7-dichlorokynurenic acid has been researched along with Allodynia in 1 studies
5,7-dichlorokynurenic acid: potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site
| Excerpt | Relevance | Reference |
|---|---|---|
| "Magnesium (Mg)-deficient rats develop a mechanical hyperalgesia which is reversed by a N-Methyl-D-Aspartate (NMDA) receptor antagonist." | 1.31 | Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats. ( Begon, S; Dubray, C; Eschalier, A; Mazur, A; Pickering, G; Rayssiguier, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Begon, S | 1 |
| Pickering, G | 1 |
| Eschalier, A | 1 |
| Mazur, A | 1 |
| Rayssiguier, Y | 1 |
| Dubray, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Magnesium Sulfate Infusion on the Quality of Recovery of Ambulatory Patients[NCT01433081] | 50 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| Does Magnesium Sulfate as a Supplement in Adductor Canal Blocks Improve Pain Control After Total Knee Arthroplasty?[NCT02581683] | Phase 4 | 130 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Opioid consumption after discharge (NCT01433081)
Timeframe: 24 hours
| Intervention | miligram morphine equivalents (Median) |
|---|---|
| Magnesium Sulfate Infusion | 10 |
| Placebo | 30 |
Quality of recovery scores post operative. Scored on a scale of 40 (poor recovery) to 200 (good recovery). (NCT01433081)
Timeframe: 24 hours post operative
| Intervention | units on scale 40 (low) - 200 (high) (Mean) |
|---|---|
| Magnesium Sulfate Infusion | 183 |
| Placebo | 159 |
1 other study available for 5,7-dichlorokynurenic acid and Allodynia
| Article | Year |
|---|---|
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Malea | 2001 |
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Malea | 2001 |
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Malea | 2001 |
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.
Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Malea | 2001 |