Page last updated: 2024-10-18

5,6-dihydroorotate and Melanoma

5,6-dihydroorotate has been researched along with Melanoma in 1 studies

4,5-dihydroorotic acid: RN given refers to cpd without isomeric designation; structure
dihydroorotic acid : A pyrimidinemonocarboxylic acid that results from the base-catalysed cyclisation of N(alpha)-carbethoxyasparagine.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cleaveland, ES1
Zaharevitz, DW1
Kelley, JA1
Paull, K1
Cooney, DA1
Ford, H1

Other Studies

1 other study available for 5,6-dihydroorotate and Melanoma

ArticleYear
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
    Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3

    Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, N

1996