5-6-7-8-tetrahydrofolic-acid and Leukemia

5-6-7-8-tetrahydrofolic-acid has been researched along with Leukemia* in 2 studies

Other Studies

2 other study(ies) available for 5-6-7-8-tetrahydrofolic-acid and Leukemia

Article	Year
Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin. Journal of medicinal chemistry, 1985, Volume: 28, Issue:7 Total syntheses from pyridine precursors of 5,10-dideazaaminopterin (1) and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin (2) are described. These compounds exhibit significant in vivo activity against L1210 leukemia that is comparable to that observed with methotrexate. Topics: Amide Synthases; Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia L1210; Ligases; Male; Methotrexate; Tetrahydrofolates; Thymidylate Synthase	1985
[SOME OBSERVATIONS ON THE BEHAVIOR OF THE ENZYMES OF THE TETRAHYDROFOLATE POOL IN THE BLOOD CELLS]. Haematologica, 1963, Volume: 48 Topics: Animals; Biomedical Research; Blood Cells; Clinical Enzyme Tests; Leukemia; Oxidoreductases; Poultry; Research; Tetrahydrofolates; Transaminases	1963

Article

Year

Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

Total syntheses from pyridine precursors of 5,10-dideazaaminopterin (1) and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin (2) are described. These compounds exhibit significant in vivo activity against L1210 leukemia that is comparable to that observed with methotrexate.

Topics: Amide Synthases; Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia L1210; Ligases; Male; Methotrexate; Tetrahydrofolates; Thymidylate Synthase

1985

[SOME OBSERVATIONS ON THE BEHAVIOR OF THE ENZYMES OF THE TETRAHYDROFOLATE POOL IN THE BLOOD CELLS].

Haematologica, 1963, Volume: 48

Topics: Animals; Biomedical Research; Blood Cells; Clinical Enzyme Tests; Leukemia; Oxidoreductases; Poultry; Research; Tetrahydrofolates; Transaminases

1963