5-6-7-8-tetrahydrofolic-acid and Leukemia

5-6-7-8-tetrahydrofolic-acid has been researched along with Leukemia* in 2 studies

Other Studies

2 other study(ies) available for 5-6-7-8-tetrahydrofolic-acid and Leukemia

ArticleYear
Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Total syntheses from pyridine precursors of 5,10-dideazaaminopterin (1) and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin (2) are described. These compounds exhibit significant in vivo activity against L1210 leukemia that is comparable to that observed with methotrexate.

    Topics: Amide Synthases; Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia L1210; Ligases; Male; Methotrexate; Tetrahydrofolates; Thymidylate Synthase

1985
[SOME OBSERVATIONS ON THE BEHAVIOR OF THE ENZYMES OF THE TETRAHYDROFOLATE POOL IN THE BLOOD CELLS].
    Haematologica, 1963, Volume: 48

    Topics: Animals; Biomedical Research; Blood Cells; Clinical Enzyme Tests; Leukemia; Oxidoreductases; Poultry; Research; Tetrahydrofolates; Transaminases

1963