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5,5-dimethyl-1-pyrroline-1-oxide and Injury, Myocardial Reperfusion

5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Injury, Myocardial Reperfusion in 9 studies

5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.

Research Excerpts

ExcerptRelevanceReference
"Deferoxamine (100 microM) was added to the perfusate just prior to reperfusion in group I, and 3 min after the start of reperfusion in group II."1.29Deferoxamine reduces the reperfusion injury in isolated neonatal rabbit hearts after hypothermic preservation. ( Abe, T; Akita, T; Kamiya, K; Katoh, S; Kodama, I; Toyama, J, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pisarenko, OI1
Lankin, VZ1
Konovalova, GG1
Serebryakova, LI1
Shulzhenko, VS1
Timoshin, AA1
Tskitishvili, OV1
Pelogeykina, YA1
Studneva, IM1
Zuo, L1
Chen, YR1
Reyes, LA1
Lee, HL1
Chen, CL1
Villamena, FA1
Zweier, JL1
Angelos, MG1
Kutala, VK1
Torres, CA1
He, G1
Stoner, JD1
Mohammad, M1
Kuppusamy, P1
Katoh, S1
Toyama, J1
Kodama, I1
Kamiya, K1
Akita, T1
Abe, T1
Bradamante, S1
Jotti, A1
Paracchini, L1
Monti, E1
Morti E [corrected to Monti, E]1
Witting, PK1
Mauk, AG1
Douglas, DJ1
Stocker, R1
Blasig, IE1
Ebert, B1
Hennig, C1
Pali, T1
Tosaki, A2
Braquet, P1
Pietri, S1
Culcasi, M1
Cozzone, PJ1

Other Studies

9 other studies available for 5,5-dimethyl-1-pyrroline-1-oxide and Injury, Myocardial Reperfusion

ArticleYear
Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion.
    Molecular and cellular biochemistry, 2014, Volume: 391, Issue:1-2

    Topics: Anesthesia; Animals; Antioxidants; Biomarkers; Catalase; Creatine Kinase, MB Form; Cyclic N-Oxides;

2014
The radical trap 5,5-dimethyl-1-pyrroline N-oxide exerts dose-dependent protection against myocardial ischemia-reperfusion injury through preservation of mitochondrial electron transport.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Cyclic N-Oxides; Dose-Response Relationship, Drug; El

2009
Hypoxic reperfusion of the ischemic heart and oxygen radical generation.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aconitate Hydratase; Allopurinol; Animals; C

2006
Deferoxamine reduces the reperfusion injury in isolated neonatal rabbit hearts after hypothermic preservation.
    Surgery today, 1993, Volume: 23, Issue:5

    Topics: Animals; Animals, Newborn; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free

1993
The hydrophilic spin trap, 5,5-dimethyl-1-pyrroline-1-oxide, does not protect the rat heart from reperfusion injury.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: Animals; Cyclic N-Oxides; Energy Metabolism; Free Radicals; In Vitro Techniques; Male; Myocardial Co

1993
Reaction of human myoglobin and peroxynitrite: characterizing biomarkers for myoglobin-derived oxidative stress.
    Biochemical and biophysical research communications, 2001, Aug-17, Volume: 286, Issue:2

    Topics: Biomarkers; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Molsidomin

2001
Inverse relationship between ESR spin trapping of oxyradicals and degree of functional recovery during myocardial reperfusion in isolated working rat heart.
    Cardiovascular research, 1990, Volume: 24, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Cyclic N-Oxides; Electron Spin Reso

1990
DMPO and reperfusion injury: arrhythmia, heart function, electron spin resonance, and nuclear magnetic resonance studies in isolated working guinea pig hearts.
    American heart journal, 1990, Volume: 120, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals;

1990
Real-time continuous-flow spin trapping of hydroxyl free radical in the ischemic and post-ischemic myocardium.
    European journal of biochemistry, 1989, Dec-08, Volume: 186, Issue:1-2

    Topics: Animals; Coronary Disease; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Mal

1989