5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Glioma in 3 studies
5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "GL261 gliomas were found to have significantly increased malondialdehyde (MDA) protein adducts (p<0." | 1.39 | Combined molecular MRI and immuno-spin-trapping for in vivo detection of free radicals in orthotopic mouse GL261 gliomas. ( De Souza, PC; Ehrenshaft, M; Gomez-Mejiba, SE; Henry, L; Lupu, F; Mason, RP; Ramirez, DC; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Towner, RA | 2 |
| Smith, N | 2 |
| Saunders, D | 2 |
| De Souza, PC | 1 |
| Henry, L | 1 |
| Lupu, F | 1 |
| Silasi-Mansat, R | 1 |
| Ehrenshaft, M | 2 |
| Mason, RP | 2 |
| Gomez-Mejiba, SE | 1 |
| Ramirez, DC | 1 |
| Coutinho de Souza, P | 1 |
| Atolagbe, O | 1 |
| Ziegler, J | 1 |
| Njoku, C | 1 |
| Lerner, M | 1 |
| Meek, B | 1 |
| Plafker, SM | 1 |
| Mamedova, N | 1 |
| Benchekroun, MN | 1 |
| Sinha, BK | 1 |
| Robert, J | 1 |
3 other studies available for 5,5-dimethyl-1-pyrroline-1-oxide and Glioma
| Article | Year |
|---|---|
Combined molecular MRI and immuno-spin-trapping for in vivo detection of free radicals in orthotopic mouse GL261 gliomas.
Topics: Albumins; Animals; Brain Neoplasms; Contrast Media; Cyclic N-Oxides; Disease Models, Animal; Free Ra | 2013 |
OKN-007 decreases free radical levels in a preclinical F98 rat glioma model.
Topics: Animals; Antioxidants; Benzenesulfonates; Contrast Media; Cyclic N-Oxides; Disease Models, Animal; F | 2015 |
Doxorubicin-induced oxygen free radical formation in sensitive and doxorubicin-resistant variants of rat glioblastoma cell lines [corrected and republished erratum originally printed in FEBS Lett 1993 May 17;322(3):295-8].
Topics: Animals; Catalase; Cyclic N-Oxides; Doxorubicin; Drug Resistance; Electron Spin Resonance Spectrosco | 1993 |