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5,5-dimethyl-1-pyrroline-1-oxide and Glial Cell Tumors

5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Glial Cell Tumors in 3 studies

5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.

Research Excerpts

ExcerptRelevanceReference
"GL261 gliomas were found to have significantly increased malondialdehyde (MDA) protein adducts (p<0."1.39Combined molecular MRI and immuno-spin-trapping for in vivo detection of free radicals in orthotopic mouse GL261 gliomas. ( De Souza, PC; Ehrenshaft, M; Gomez-Mejiba, SE; Henry, L; Lupu, F; Mason, RP; Ramirez, DC; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Towner, RA2
Smith, N2
Saunders, D2
De Souza, PC1
Henry, L1
Lupu, F1
Silasi-Mansat, R1
Ehrenshaft, M2
Mason, RP2
Gomez-Mejiba, SE1
Ramirez, DC1
Coutinho de Souza, P1
Atolagbe, O1
Ziegler, J1
Njoku, C1
Lerner, M1
Meek, B1
Plafker, SM1
Mamedova, N1
Benchekroun, MN1
Sinha, BK1
Robert, J1

Other Studies

3 other studies available for 5,5-dimethyl-1-pyrroline-1-oxide and Glial Cell Tumors

ArticleYear
Combined molecular MRI and immuno-spin-trapping for in vivo detection of free radicals in orthotopic mouse GL261 gliomas.
    Biochimica et biophysica acta, 2013, Volume: 1832, Issue:12

    Topics: Albumins; Animals; Brain Neoplasms; Contrast Media; Cyclic N-Oxides; Disease Models, Animal; Free Ra

2013
OKN-007 decreases free radical levels in a preclinical F98 rat glioma model.
    Free radical biology & medicine, 2015, Volume: 87

    Topics: Animals; Antioxidants; Benzenesulfonates; Contrast Media; Cyclic N-Oxides; Disease Models, Animal; F

2015
Doxorubicin-induced oxygen free radical formation in sensitive and doxorubicin-resistant variants of rat glioblastoma cell lines [corrected and republished erratum originally printed in FEBS Lett 1993 May 17;322(3):295-8].
    FEBS letters, 1993, Jul-12, Volume: 326, Issue:1-3

    Topics: Animals; Catalase; Cyclic N-Oxides; Doxorubicin; Drug Resistance; Electron Spin Resonance Spectrosco

1993