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5,5-dimethyl-1-pyrroline-1-oxide and Alzheimer Disease

5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Alzheimer Disease in 1 studies

5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franceschi, C1
Monti, D1
Cossarizza, A1
Tomasi, A1
Sola, P1
Zannotti, M1

Other Studies

1 other study available for 5,5-dimethyl-1-pyrroline-1-oxide and Alzheimer Disease

ArticleYear
Oxidative stress, poly(ADP)ribosylation and aging: in vitro studies on lymphocytes from normal and Down's syndrome subjects of different age and from patients with Alzheimer's dementia.
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Child; Cyclic N-Oxides; Down S

1990