Compounds > 5,5-dimethyl-1-pyrroline-1-oxide
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5,5-dimethyl-1-pyrroline-1-oxide and Agranulocytosis

5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Agranulocytosis in 2 studies

5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"Aminoglutethimide (AG) is a first-generation aromatase inhibitor used for estrogen-dependent breast cancer."5.34Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. ( Bonini, MG; Ehrenshaft, M; Jiang, J; Mason, RP; Siraki, AG, 2007)
"Aminoglutethimide (AG) is a first-generation aromatase inhibitor used for estrogen-dependent breast cancer."1.34Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. ( Bonini, MG; Ehrenshaft, M; Jiang, J; Mason, RP; Siraki, AG, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Siraki, AG2
Jiang, J2
Mason, RP2
Bonini, MG1
Ehrenshaft, M1

Other Studies

2 other studies available for 5,5-dimethyl-1-pyrroline-1-oxide and Agranulocytosis

ArticleYear
Investigating the mechanisms of aromatic amine-induced protein free radical formation by quantitative structure-activity relationships: implications for drug-induced agranulocytosis.
    Chemical research in toxicology, 2010, May-17, Volume: 23, Issue:5

    Topics: Agranulocytosis; Aniline Compounds; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radi

2010
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.
    Chemical research in toxicology, 2007, Volume: 20, Issue:7

    Topics: Adenosine Triphosphate; Agranulocytosis; Aminoglutethimide; Aniline Compounds; Aromatase Inhibitors;

2007