5-10-methylenetetrahydrofolic-acid and Pregnancy--Ectopic

5-10-methylenetetrahydrofolic-acid has been researched along with Pregnancy--Ectopic* in 1 studies

Other Studies

1 other study(ies) available for 5-10-methylenetetrahydrofolic-acid and Pregnancy--Ectopic

ArticleYear
The effect of parental 5,10-methylenetetrahydrofolate reductase 677C/T and 1298A/C gene polymorphisms on response to single-dose methotrexate in tubal ectopic pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2017, Volume: 30, Issue:10

    The aim of this study was to assess the effect of parental 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms (677C/T and 1298A/C) on response to single-dose methotrexate (MTX) treatment in tubal ectopic pregnancy (TEP).. In this prospective cohort study, cases with unruptured TEPs were grouped into two according to their response to single-dose MTX treatment (Group 1: responsive, n:88; Group 2: unresponsive, n:21). The groups were compared with regard to baseline demographic and clinical parameters. As a main outcome measure, the independent effects of parental MTHFR gene polymorphisms on response to single dose MTX treatment were evaluated.. Parental MTHFR 677C/T and 1298A/C mutations do not predict the outcome of single dose intramuscular MTX treatment in unruptured TEP.

    Topics: Abortifacient Agents, Nonsteroidal; Adult; Case-Control Studies; Chorionic Gonadotropin, beta Subunit, Human; Female; Humans; Methotrexate; Mutation; Polymorphism, Genetic; Pregnancy; Pregnancy, Ectopic; Prospective Studies; Regression Analysis; Tetrahydrofolates

2017