5'-methylthioadenosine and Neoplasms

5'-methylthioadenosine has been researched along with Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Aranda, R; Bobinski, TP; Briere, DM; Burns, AC; Christensen, JG; Clarine, J; Engstrom, LD; Gunn, RJ; Ivetac, A; Jean-Baptiste, R; Ketcham, JM; Kobayashi, M; Kuehler, J; Kulyk, S; Lawson, JD; Marx, MA; Moya, K; Olson, P; Rahbaek, L; Smith, CR; Thomas, NC; Wang, X; Waters, LM1
Bielski, CM; Boehm, JS; Bradner, JE; Clish, CB; Cowley, GS; Dennis, C; Fitzgerald, ME; Garraway, LA; Golub, TR; Hahn, WC; Kryukov, GV; Marlow, SE; Paulk, J; Root, DE; Ruth, JR; Scott, JM; Tanaka, M; Tsherniak, A; Vazquez, F; Weir, BA; Wilson, FH1
Billy, E; Capka, V; Cho, YS; Ciccone, D; Crawford, K; deBeaumont, R; deWeck, A; Gao, H; Gu, J; Ho, S; Hoffman, GR; Hofmann, F; Hurov, K; Keen, N; Kipp, DR; Lai, A; Lees, E; Lin, F; Lin, Y; Liu, Y; Mavrakis, KJ; McAllister, G; McDonald, ER; McNamara, JT; Mickanin, C; Pagliarini, R; Porter, JA; Ruddy, DA; Schlabach, MR; Schmelzle, T; Sellers, WR; Sprague, ER; Stegmeier, F; Stump, M; Tallarico, J; Venkatesan, K; Vitari, AC; Yan-Neale, Y; Yang, G; Yin, H; Yu, J; Yue, Y; Zhao, S; Zheng, B1
Avila, MA; Corrales, FJ; García-Trevijano, ER; Lu, SC; Mato, JM1
Akaoka, I; Fujimori, S; Kamatani, N; Kaneko, K1
Tisdale, MJ1
Galletti, P; Seidenfeld, J; Williams-Ashman, HG1
Akaoka, I; Fujimori, S; Kamatani, N; Kaneko, K; Kumakawa, T1
Akaoka, I; Fujii, H; Fujimori, S; Kamatani, N; Kanbayashi, T; Kaneko, K; Kumakawa, T; Miwa, S; Miyazawa, Y1
Carrera, CJ; Carson, DA; Kajander, EO; Kubota, M; Nobori, T; Yamanaka, H1
Frost, P; Judde, JG1

Reviews

3 review(s) available for 5'-methylthioadenosine and Neoplasms

ArticleYear
Methylthioadenosine.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:11

    Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Humans; Methionine; Neoplasms; Purines; S-Adenosylhomocysteine; Thionucleosides

2004
Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine.
    Biochemical pharmacology, 1982, Feb-01, Volume: 31, Issue:3

    Topics: Adenosine; Animals; Deoxyadenosines; Female; Humans; Male; Neoplasms; Purine-Nucleoside Phosphorylase; Rats; Ribosemonophosphates; S-Adenosylmethionine; Spermidine; Spermine; Thioglycosides; Thionucleosides

1982
Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy.
    Advances in experimental medicine and biology, 1988, Volume: 250

    Topics: Adenosine; Animals; Deoxyadenosines; Humans; Neoplasms; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Thionucleosides

1988

Other Studies

8 other study(ies) available for 5'-methylthioadenosine and Neoplasms

ArticleYear
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxyadenosines; Female; Gene Deletion; Humans; Mice, Nude; Neoplasms; Phthalazines; Protein Binding; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; Thionucleosides; Xenograft Model Antitumor Assays

2022
MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
    Science (New York, N.Y.), 2016, Mar-11, Volume: 351, Issue:6278

    Topics: Cell Line, Tumor; Deoxyadenosines; Enzyme Inhibitors; Gene Deletion; Humans; Isoquinolines; Neoplasms; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; Pyrimidines; Thionucleosides; Transcription Factors

2016
Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
    Science (New York, N.Y.), 2016, Mar-11, Volume: 351, Issue:6278

    Topics: Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Deoxyadenosines; Gene Deletion; Humans; Methionine; Neoplasms; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; RNA, Small Interfering; Thionucleosides

2016
5'-Methylthioadenosine in urine from normal subjects and cancer patients.
    Biochimica et biophysica acta, 1984, Nov-28, Volume: 802, Issue:2

    Topics: Adenosine; Chromatography, High Pressure Liquid; Deoxyadenosines; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Neoplasms; Thionucleosides

1984
Methionine synthesis from 5'-methylthioadenosine by tumour cells.
    Biochemical pharmacology, 1983, Oct-01, Volume: 32, Issue:19

    Topics: Adenosine; Animals; Carbon Radioisotopes; Cell Line; Cells, Cultured; Deoxyadenosines; Humans; Kinetics; Leukemia; Methionine; Mice; Neoplasms; Thionucleosides; Urinary Bladder Neoplasms

1983
Disturbance in the metabolism of 5'-methylthioadenosine and adenine in patients with neoplastic diseases, and in those with a deficiency in adenine phosphoribosyltransferase.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:9

    Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adult; Aged; Deoxyadenosines; Female; Humans; Leukemia; Male; Middle Aged; Neoplasms; Osmolar Concentration; Thionucleosides

1991
Measurement of 5'-methylthioadenosine in patients with neoplasms.
    International journal of cancer, 1990, Jan-15, Volume: 45, Issue:1

    Topics: Adenosine; Adult; Aged; Analysis of Variance; Chromatography, High Pressure Liquid; Deoxyadenosines; Female; Humans; Male; Middle Aged; Neoplasms; Remission Induction; Thionucleosides

1990
Patterns of methionine auxotrophy in normal and neoplastic cells: the methionine independence of lymphocyte mitogenesis and low frequency of the methionine-dependent phenotype in human tumors.
    Cancer research, 1988, Dec-01, Volume: 48, Issue:23

    Topics: Adenosine; Animals; Culture Media; Deoxyadenosines; Humans; Lymphocyte Activation; Methionine; Mice; Neoplasms; Phenotype; Thionucleosides; Tumor Cells, Cultured

1988